Understanding the intracellular effect of enhanced nutrient feeding toward high titer antibody production process

Cell line-specific control of recombinant monoclonal antibody production by CHO cells

(2010) Peter M. O'Callaghan et al.   BIOTECHNOLOGY AND BIOENGINEERING

Mechanisms of unintended amino acid sequence changes in recombinant monoclonal antibodies expressed in Chinese Hamster Ovary (CHO) cells

(2010) Donglin Guo et al.   BIOTECHNOLOGY AND BIOENGINEERING

Maximizing productivity of CHO cell-based fed-batch culture using chemically defined media conditions and typical manufacturing equipment

(2010) Yao-Ming Huang et al.   BIOTECHNOLOGY PROGRESS

Metabolomics-driven approach for the improvement of Chinese hamster ovary cell growth: Overexpression of malate dehydrogenase II

(2010) William P.K. Chong et al.   JOURNAL OF BIOTECHNOLOGY

Generation of stable cell lines by site-specific integration of transgenes into engineered Chinese hamster ovary strains using an FLP-FRT system

(2010) Hong Zhou et al.   JOURNAL OF BIOTECHNOLOGY

CHO gene expression profiling in biopharmaceutical process analysis and design

(2009) Jochen Schaub et al.   BIOTECHNOLOGY AND BIOENGINEERING

Development of a high throughput protein a well-plate purification method for monoclonal antibodies

(2009) Jennifer Hopp et al.   BIOTECHNOLOGY PROGRESS

Metabolic characterization of a hyper-productive state in an antibody producing NS0 myeloma cell line

(2009) Soo Hean Gary Khoo et al.   METABOLIC ENGINEERING

Identification of novel small molecule enhancers of protein production by cultured mammalian cells

(2008) Martin J. Allen et al.   BIOTECHNOLOGY AND BIOENGINEERING

Detailed understanding of enhanced specific antibody productivity in NS0 myeloma cells

(2008) Soo Hean Gary Khoo et al.   BIOTECHNOLOGY AND BIOENGINEERING

A clone screening method using mRNA levels to determine specific productivity and product quality for monoclonal antibodies

(2008) Christina J. Lee et al.   BIOTECHNOLOGY AND BIOENGINEERING

An XBP-1 dependent bottle-neck in production of IgG subtype antibodies in chemically defined serum-free Chinese hamster ovary (CHO) fed-batch processes

(2008) E BECKER et al.   JOURNAL OF BIOTECHNOLOGY

Enhanced Human Thrombopoietin Production by Sodium Butyrate Addition to Serum-Free Suspension Culture of Bcl-2-Overexpressing CHO Cells

(2005) Yun Hee Sung et al.   BIOTECHNOLOGY PROGRESS

On the Optimal Ratio of Heavy to Light Chain Genes for Efficient Recombinant Antibody Production by CHO Cells

(2005) Stefan Schlatter et al.   BIOTECHNOLOGY PROGRESS

Effects of Elevated pCO2 and Osmolality on Growth of CHO Cells and Production of Antibody-Fusion Protein B1: A Case Study

(2005) Marie M. Zhu et al.   BIOTECHNOLOGY PROGRESS