Evaluation of protein engineering and process optimization approaches to enhance antibody drug manufacturability

Potential aggregation prone regions in biotherapeutics

(2010) Xiaoling Wang et al.   mAbs

Discovery and Characterization of a Peptide Motif That Specifically Recognizes a Non-native Conformation of Human IgG Induced by Acidic pH Conditions

(2009) Kotaro Sakamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Investigation of protein binding affinity in multimodal chromatographic systems using a homologous protein library

(2009) Wai Keen Chung et al.   JOURNAL OF CHROMATOGRAPHY A

Quality by design for biopharmaceuticals

(2009) Anurag S Rathore et al.   NATURE BIOTECHNOLOGY

Investigation of protein binding affinity and preferred orientations in ion exchange systems using a homologous protein library

(2008) Wai Keen Chung et al.   BIOTECHNOLOGY AND BIOENGINEERING

Dual effects of Tween 80 on protein stability

(2007) Wei Wang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Comparison of standard and new generation hydrophobic interaction chromatography resins in the monoclonal antibody purification process

(2007) Jie Chen et al.   JOURNAL OF CHROMATOGRAPHY A