Ectopic expression of human mTOR increases viability, robustness, cell size, proliferation, and antibody production of chinese hamster ovary cells

mAbs

(2010) Pablo A. Scolnik   mAbs

Mcl-1 overexpression leads to higher viabilities and increased production of humanized monoclonal antibody in Chinese hamster ovary cells

(2009) Brian S. Majors et al.   BIOTECHNOLOGY PROGRESS

DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival

(2009) Timothy R. Peterson et al.   CELL

Heat-stable oral alga-based vaccine protects mice from Staphylococcus aureus infection

(2009) Imke A.J. Dreesen et al.   JOURNAL OF BIOTECHNOLOGY

Molecular mechanisms of mTOR-mediated translational control

(2009) Xiaoju Max Ma et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Rapamycin induces transactivation of the EGFR and increases cell survival

(2009) D Chaturvedi et al.   ONCOGENE

Epigenetic Engineering of Ribosomal RNA Genes Enhances Protein Production

(2009) Raffaella Santoro et al.   PLoS One

The role of Bcl-2 and its combined effect with p21CIP1 in adaptation of CHO cells to suspension and protein-free culture

(2008) Kelly Astley et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Enhancement of transient gene expression and culture viability using Chinese hamster ovary cells overexpressing Bcl-xL

(2008) Brian S. Majors et al.   BIOTECHNOLOGY AND BIOENGINEERING

Molecular engineering of exocytic vesicle traffic enhances the productivity of Chinese hamster ovary cells

(2008) Ren-Wang Peng et al.   BIOTECHNOLOGY AND BIOENGINEERING

Detailed understanding of enhanced specific antibody productivity in NS0 myeloma cells

(2008) Soo Hean Gary Khoo et al.   BIOTECHNOLOGY AND BIOENGINEERING

Monoclonal Antibody Pharmacokinetics and Pharmacodynamics

(2008) W Wang et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

E2F-1 overexpression increases viable cell density in batch cultures of Chinese hamster ovary cells

(2008) Brian S. Majors et al.   JOURNAL OF BIOTECHNOLOGY

Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation

(2008) A. Y. Choo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1

(2008) Y. Sancak et al.   SCIENCE