Antibody humanization methods – a review and update

A humanized IgG but not IgM antibody is effective in prophylaxis and therapy of yellow fever infection in an AG129/17D-204 peripheral challenge mouse model

(2012) Brett A. Thibodeaux et al.   ANTIVIRAL RESEARCH

scFv Antibody: Principles and Clinical Application

(2012) Zuhaida Asra Ahmad et al.   Clinical & Developmental Immunology

Development of a Humanized Antibody with High Therapeutic Potential against Dengue Virus Type 2

(2012) Pi-Chun Li et al.   PLoS Neglected Tropical Diseases

Humanizing murine IgG3 anti-GD2 antibody m3F8 substantially improves antibody-dependent cell-mediated cytotoxicity while retaining targeting in vivo

(2012) Nai-Kong V. Cheung et al.   OncoImmunology

Production and Characterization of a Humanized Single-chain Antibody against Human Integrin αvβ3 Protein

(2011) Dabin Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Humanization and Characterization of an Anti-Human TNF-α Murine Monoclonal Antibody

(2011) Wei-Chun Chiu et al.   PLoS One

Development of an EGFRvIII specific recombinant antibody

(2010) Puja Gupta et al.   BMC BIOTECHNOLOGY

The Human Immune Response to Dengue Virus Is Dominated by Highly Cross-Reactive Antibodies Endowed with Neutralizing and Enhancing Activity

(2010) Martina Beltramello et al.   Cell Host & Microbe

The immunogenicity of humanized and fully human antibodies

(2010) Fiona A. Harding et al.   mAbs

A Humanized Anti-VEGF Rabbit Monoclonal Antibody Inhibits Angiogenesis and Blocks Tumor Growth in Xenograft Models

(2010) Yanlan Yu et al.   PLoS One

Design and Activity of a Murine and Humanized Anti-CEACAM6 Single-Chain Variable Fragment in the Treatment of Pancreatic Cancer

(2009) C. J. Riley et al.   CANCER RESEARCH

Affinity Maturation of a Humanized Rat Antibody for Anti-RAGE Therapy: Comprehensive Mutagenesis Reveals a High Level of Mutational Plasticity Both Inside and Outside the Complementarity-Determining Regions

(2009) William J. Finlay et al.   JOURNAL OF MOLECULAR BIOLOGY

Stabilization and humanization of a single-chain Fv antibody fragment specific for human lymphocyte antigen CD19 by designed point mutations and CDR-grafting onto a human framework

(2009) Markus Kügler et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Germline humanization of a murine Aβ antibody and crystal structure of the humanized recombinant Fab fragment

(2009) Remy Robert et al.   PROTEIN SCIENCE

Efficacy and safety of golimumab in patients with ankylosing spondylitis: Results of a randomized, double-blind, placebo-controlled, phase III trial

(2008) Robert D. Inman et al.   ARTHRITIS AND RHEUMATISM

Construction of multiform scFv antibodies using linker peptide

(2008) Shihua Wang et al.   Journal of Genetics and Genomics

Germline Humanization of a Non-human Primate Antibody that Neutralizes the Anthrax Toxin, by in Vitro and in Silico Engineering

(2008) Thibaut Pelat et al.   JOURNAL OF MOLECULAR BIOLOGY

Anti-estradiol-17β single-chain Fv fragments: Generation, characterization, gene randomization, and optimized phage display

(2008) Norihiro Kobayashi et al.   STEROIDS

Modifying specificity of antidigoxin antibodies using insertional mutagenesis

(2002) Rustem A. Krykbaev et al.   PROTEIN SCIENCE