Cyclin-Dependent Kinases as Drug Targets for Cell Growth and Proliferation Disorders. A Role for Systems Biology Approach in Drug Development. Part II—CDKs as Drug Targets in Hypertrophic Cell Growth. Modelling of Drugs Targeting CDKs

Alterations in Protein P53 Expression During the Development of Pressure Overload-Induced Left Ventricular Hypertrophy in Rats

(2014) V. Stoyanova et al.   BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT

Anti-angiogenic effects of purine inhibitors of cyclin dependent kinases

(2011) Johanna Liebl et al.   ANGIOGENESIS

Nothing in Excess—Lessons Learned from the Expression of High-Mobility Group Proteins Type a in Non-Cancer and Cancer Cells

(2011) Rumena Petkova et al.   BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT

Roscovitine blocks leukocyte extravasation by inhibition of cyclin-dependent kinases 5 and 9

(2011) Nina Berberich et al.   BRITISH JOURNAL OF PHARMACOLOGY

A novel quantitative systems biology approach to cancer research and treatment

(2011) Robert Clyde et al.   CURRENT OPINION IN BIOTECHNOLOGY

Functional Variants of the HMGA1 Gene and Type 2 Diabetes Mellitus

(2011) Eusebio Chiefari   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Discovering the Targets of Drugs Via Computational Systems Biology: FIGURE 1.

(2011) Hon Nian Chua et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modeling the competition between lung metastases and the immune system using agents

(2010) Marzio Pennisi et al.   BMC BIOINFORMATICS

The executable pathway to biological networks

(2010) J. Fisher et al.   Briefings in Functional Genomics

Role of the cyclin-dependent kinase 9-related pathway in mammalian gene expression and human diseases

(2010) Gaetano Romano et al.   CELL CYCLE

Discovery and Characterization of 2-Anilino-4- (Thiazol-5-yl)Pyrimidine Transcriptional CDK Inhibitors as Anticancer Agents

(2010) Shudong Wang et al.   CHEMISTRY & BIOLOGY

Cell Cycle as a Target of Antineoplastic Drugs

(2010) Maria De Falco et al.   CURRENT PHARMACEUTICAL DESIGN

Inhibition of CDKS by roscovitine suppressed LPS-induced ·NO production through inhibiting NFκB activation and BH4 biosynthesis in macrophages

(2009) Jianhai Du et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Inhibition of cyclin-dependent kinases by olomoucine and roscovitine reduces lipopolysaccharide-induced inflammatory responses via down-regulation of nuclear factor κB

(2009) R-S. Jhou et al.   CELL PROLIFERATION

Cell Lineages and the Logic of Proliferative Control

(2009) Arthur D Lander et al.   PLOS BIOLOGY

Modelling metabolic networks using power-laws and S-systems

(2008) Eberhard O. Voit   Essays in Biochemistry

Cyclin-dependent kinase 9: a key transcriptional regulator and potential drug target in oncology, virology and cardiology

(2008) S WANG et al.   TRENDS IN PHARMACOLOGICAL SCIENCES