Article
Chemistry, Physical
Alessandro Giussani, Stoffel D. Janssens, David Vazquez-Cortes, Eliot Fried
Summary: In this study, diamond films were deposited on Si(001) substrates using microwave plasma enhanced chemical vapor deposition, and the interaction between nanodiamonds and plasma was investigated. The results show that under lower chamber pressure and the presence of diamond precursor layer, the induction time for film growth can be significantly shortened.
APPLIED SURFACE SCIENCE
(2022)
Article
Chemistry, Physical
Cynthia Melendrez, Jorge A. Lopez-Rosas, Camron X. Stokes, Tsz Ching Cheung, Sang-Jun Lee, Charles James Titus, Jocelyn Valenzuela, Grace Jeanpierre, Halim Muhammad, Polo Tran, Perla Jasmine Sandoval, Tyanna Supreme, Virginia Altoe, Jan Vavra, Helena Raabova, Vaclav Vanek, Sami Sainio, William B. Doriese, Galen C. O'Neil, Daniel S. Swetz, Joel N. Ullom, Kent Irwin, Dennis Nordlund, Petr Cigler, Abraham Wolcott
Summary: The bromination of high-pressure, high-temperature nanodiamond surfaces has not been studied before, but it can enhance chemical reactivity and the formation of covalent bonds in the diamond lattice. By utilizing the bromination reaction, a tertiary-alcohol-rich nanodiamond surface was transformed into an amine surface. The alkyl bromide moieties on the surface of HPHT NDs are highly reactive and can form diamond-nitrogen bonds at room temperature.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2022)
Article
Chemistry, Multidisciplinary
Hoi Man Leung, Hoi Ching Chu, Zheng-Wei Mao, Pik Kwan Lo
Summary: Nanodiamonds are carbon-based nanoparticles in nanomedicine that have gained attention for their unique features including versatility, opto-magnetic properties, stability, low cytotoxicity, affinity to biomolecules, and biocompatibility. This article discusses the opto-magnetic properties of negatively charged nitrogen vacancy (NV-) centers in nanodiamonds as fluorescence probes. It also explores the chemical methods for surface modification of nanodiamonds relevant to biomedical applications and highlights their biocompatibility. Furthermore, it provides an overview of recent biomedical applications of nanodiamonds as tools for bioimaging, targeting nanocarriers, and various therapies.
CHEMICAL COMMUNICATIONS
(2023)
Article
Chemistry, Analytical
Chao Zhang, Asta Zukauskaite, Ivan Petrik, Ales Pencik, Martin Honig, Jiri Gruz, Jitka Siroka, Ondrej Novak, Karel Dolezal
Summary: Phytohormones play a crucial role in plant development and stress responses. DESI-MSI has been used for direct detection of wound-induced phytohormones in intact leaves, showing increased levels of various phytohormones in wounded areas compared to control leaves. The results suggest a potential correlation between different phytohormone species and their precursors under mechanical stress.
Review
Engineering, Chemical
Wioletta Parys, Malgorzata Dolowy, Alina Pyka-Pajak
Summary: This study summarizes the new strategies of liquid and gas chromatography methods for the identification and quantitative determination of natural and synthetic bioactive compounds in food products from 2019 to 2021. The review highlights the significant role of HPLC methodology in combination with different detection modes in characterizing the chemical composition of food and in the multi-residue analysis of various compounds.
Article
Biochemical Research Methods
Aleksandra N. Koreshkova, Vipul Gupta, Anton Peristyy, Rafal J. Wrobel, Brett Paull, Pavel N. Nesterenko
Summary: The adsorption and chromatographic properties of oxidized and hydrogenated high pressure and high temperature synthesized diamond were studied using high-performance liquid chromatography. The results showed that both adsorbents had moderate polarity and a mixed-mode retention mechanism. Unexpectedly, hydrogenated diamond exhibited significant anion-exchange properties under acidic conditions and cation-exchange properties under alkaline conditions, while only cation-exchange selectivity was observed for oxidized diamond across the entire pH range.
JOURNAL OF CHROMATOGRAPHY A
(2022)
Article
Chemistry, Analytical
Nitish Sharma, Divya Kukreja, Tushar Giri, Sumit Kumar, Ravi P. Shah
Summary: This review provides an overview of peptide degradation and method development using various chromatographic techniques. It discusses in detail the parameters and variables that need to be considered in method development, as well as provides a guide on selecting chromatographic parameters.
JOURNAL OF SEPARATION SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Clifford Young, Mark R. Condina, Matthew T. Briggs, Edward S. X. Moh, Gurjeet Kaur, Martin K. Oehler, Peter Hoffmann
Summary: Protein glycosylation plays a crucial role in biological processes, with liquid chromatography-mass spectrometry being a commonly used technique for N-glycan analysis. The study demonstrates the utility of in-house packed PGC columns for robust and reproducible LC-MS analysis of N-glycans, highlighting the importance of studying N-glycan structures in ovarian cancer tissues.
FRONTIERS IN CHEMISTRY
(2021)
Article
Biochemical Research Methods
Matthew J. Sorensen, Mellie June Paulines, Todd D. Maloney
Summary: This study evaluated the orthogonality between ion-pair reversed phase (IP-RP), anion exchange (AEX), and hydrophilic interaction liquid chromatography (HILIC) for the separation of oligonucleotides. The results showed that coupling HILIC with either AEX or IP-RP provided the highest degree of orthogonality.
JOURNAL OF CHROMATOGRAPHY A
(2023)
Article
Chemistry, Analytical
Yawen Li, Ru Lian, Feiyu Yang, Zhiru Xu, Fangqi Cao, Rong Wang, Chen Liang, Yurong Zhang
Summary: A new method for the rapid quantitation of three synthetic cathinones in urine was established using magnetic dispersive solid-phase extraction combined with direct analysis in real time and high-resolution mass spectrometry. The method showed high precision, stability, and accuracy, and was successfully applied to detect the synthetic cathinones in rat urine.
ANALYTICAL METHODS
(2021)
Article
Materials Science, Multidisciplinary
V. A. Plotnikov, D. G. Bogdanov, A. S. Bogdanov, A. A. Chepurov, S. V. Makarov, A. P. Yelisseyev, E. I. Zhimulev, V. G. Vins
Summary: The research aims to study the thermal conductivity of detonation nanodiamonds-based composites. The thermal conductivity of nanodiamond composites is considerably lower than diamond monocrystals and shows almost no changes in a specific temperature range. This temperature dependence is related to the phonon spectrum characteristics of diamond monocrystals and the size of nanocrystals.
LETTERS ON MATERIALS
(2022)
Article
Chemistry, Analytical
B. N. Sundberg, R. Pause, I. D. van der Werf, A. Astefanei, K. J. van den Berg, M. R. van Bommel
Summary: Several analytical techniques have been compared for the identification of historical synthetic organic pigments (SOPs). The results indicate that specific combinations of analytical techniques are required for confident SOP identifications. The use of HRMS was found to be critical for the elucidation of unknown SOPs.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Inorganic & Nuclear
Balasubramanian Sriram, Jeena N. Baby, Sea-Fue Wang, Yung-Fu Hsu, Abhikha Sherlin, Mary George
Summary: The overuse of antibiotics has negative consequences on ecosystems, but the synthesis of YVO4@CN nanocomposite in this study has effectively detected DMZ, showcasing potential for real-time sample analysis of nitroimidazole drugs.
INORGANIC CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Abdoul Kader Alassane Moussa, Sener Saglam, Aysem Uzer, Resat Apak
Summary: A novel electrochemical method was developed for the determination of nitroguanidine (NG) using a modified glassy carbon electrode surface. The method showed sensitivity and selectivity, and was successfully applied in various samples with high recoveries.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Analytical
Zahra Gholami, Mohammad Hossein Marhamatizadeh, Saeed Yousefinejad, Marzieh Rashedinia, Seyed Mohammad Mazloomi
Summary: For the first time, deep eutectic solvents were utilized in the concurrent extraction and separation of eight common synthetic dyes in jellies and drinks, showing higher efficiency and accuracy in dye extraction and measurement, making it a promising new method to be adopted in food quality control laboratories.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
Oleg V. Rodinkov, Alexey Y. Pisarev, Leonid N. Moskvin, Aleksandra S. Bugaichenko, Pavel N. Nesterenko
Summary: A novel approach in headspace gas chromatographic analysis was developed, which utilizes the selective absorption of gas extractant to remove carbon dioxide during analyte concentration, resulting in increased preconcentration of analytes and decreased limits of detection.
Article
Biochemical Research Methods
Aleksandra N. Koreshkova, Vipul Gupta, Anton Peristyy, Rafal J. Wrobel, Brett Paull, Pavel N. Nesterenko
Summary: The adsorption and chromatographic properties of oxidized and hydrogenated high pressure and high temperature synthesized diamond were studied using high-performance liquid chromatography. The results showed that both adsorbents had moderate polarity and a mixed-mode retention mechanism. Unexpectedly, hydrogenated diamond exhibited significant anion-exchange properties under acidic conditions and cation-exchange properties under alkaline conditions, while only cation-exchange selectivity was observed for oxidized diamond across the entire pH range.
JOURNAL OF CHROMATOGRAPHY A
(2022)
Article
Chemistry, Analytical
Viktoriia D. Luzanova, Nina B. Rozhmanova, Yuri V. Volgin, Pavel N. Nesterenko
Summary: A HPLC method using a faujasite-packed column and methanol as eluent was developed for direct determination of water impurities in various organic solvents. Water peaks were detected by refractometry or indirect spectrophotometry at 204 nm. The method achieved a LOD and LOQ of 0.001 wt% and 0.0033 wt% respectively for a 20 μL sample volume and obtained a linear calibration plot (R2 = 0.9998) for water content between 0.01 and 9.55 wt%. The method was successfully applied to the analysis of polar organic solvents including acetonitrile, nitromethane, 1,4-dioxane, 2-ethoxyethanol, methanol, dimethyl sulfoxide (DMSO), ethanol and 2-propanol.
ANALYTICA CHIMICA ACTA
(2023)
Article
Biochemistry & Molecular Biology
Nikita Sarvin, Ruslan Puzankov, Georgii Vasiyarov, Pavel N. Nesterenko, Sergey M. Staroverov
Summary: Macrocyclic glycopeptide antibiotics immobilized on silica are effective stationary phases for chiral recognition and HPLC separation. The enantioselectivity depends on the ligand structure, immobilization chemistry, and separation conditions. In this study, three new chiral stationary phases based on eremomycin were prepared and investigated for enantioseparation of amino acids. The chloreremomycin-based stationary phase demonstrated the most successful chiral recognition, and efficient enantioselective separation of amino acids was achieved using pure water as the eluent.
Article
Chemistry, Analytical
Lewellwyn J. Coates, Andrew Gooley, Shing Chung Lam, Boyjie Firme, Paul R. Haddad, Hans-Jurgen Wirth, Angel Diaz, Frank Riley, Brett Paull
Summary: Due to their size, conventional high performance liquid chromatographs (HPLCs) are difficult to place close to a reaction vessel within a pharmaceutical manufacturing or development site. However, a compact and modular separation system using capillary HPLC has been developed to enable co-location of an HPLC with a small-scale reactor for reaction monitoring. The compact system showed equivalent quantitative performance to an Agilent 1290 Infinity II HPLC system.
ANALYTICA CHIMICA ACTA
(2023)
Article
Biochemistry & Molecular Biology
Maria Zorina, Victor V. Dotsenko, Pavel N. Nesterenko, Azamat Temerdashev, Ekaterina Dmitrieva, Yu-Qi Feng, Sanka N. Atapattu
Summary: In this study, phthalylglycyl chloride was proposed as a derivatization agent for the determination of octopamine, adrenaline, and dopamine in urine for the first time. The derivatization process combined reversed-phase liquid chromatography with positive electrospray ionization-high-resolution mass spectrometry. An LC-HRMS method with quantification limits of 5 ng/mL and detection limits of 1.5 ng/mL for all analytes was developed. The derivatization with phthalylglycyl chloride at pH 6.5 and 30 degrees C resulted in a 95-97% yield of derivatives. The proposed method was successfully applied to the analysis of human urine samples and compared with conventional derivatization procedures using 9-fluorenyl-methoxycarbonyl chloride and dansyl chloride.
Article
Chemistry, Multidisciplinary
Liang Wu, Arushi Manchanda, Vipul Gupta, Brett Paull
Summary: A novel thread-based electrofluidic analytical method incorporating isotachophoresis (ITP) and graphene oxide (GO) surfacefunctionalized zones on nylon threads was developed for DNA hybridization. The method demonstrated quantitative trapping and visualization of hybridized DNA bands, allowing potential applications in point-of-care (POC) diagnostic devices.
Article
Biochemical Research Methods
Ibraam E. Mikhail, Mohamed Hemida, Leo Lebanov, Snezhana Astrakhantseva, Vipul Gupta, Philip Hortin, John S. Parry, Mirek Macka, Brett Paull
Summary: A novel approach for multi-wavelength ultraviolet absorbance detection using a single board computer and a field programmable gate array is introduced. The method shows excellent linearity and can simultaneously determine multiple compounds in pharmaceutical analysis.
JOURNAL OF CHROMATOGRAPHY A
(2023)
Review
Chemistry, Analytical
Mohamed Hemida, Alireza Ghiasvand, Mirek Macka, Vipul Gupta, Paul R. Haddad, Brett Paull
Summary: Liquid chromatography is a widely used analytical technique in separation science and chemical analysis, and there has been an increasing interest in miniaturizing this technique in recent years. This has been made possible by the development of new miniature and portable detection technologies, allowing for on-site and portable analyses. Significant advancements have been made in the miniaturization of liquid chromatography with photometric, electrochemical, and mass spectrometric detection, leading to the development of field-deployable and portable instruments for various applications. This review provides an overview of recent developments in the miniaturization of detection systems for portable liquid chromatographic systems, along with critical comments and expected future trends.
JOURNAL OF SEPARATION SCIENCE
(2023)
Article
Chemistry, Analytical
Oleg Rodinkov, Victor Postnov, Valery Spivakovskyi, Ekaterina Znamenskaya, Anastasia Zheludovskaya, Pavel Nesterenko
Summary: A new scheme for rapid preconcentration and determination of volatile organic substances in air using flame ionization detector is proposed. The scheme involves changing the geometry of the adsorbent layer from adsorption to thermal desorption and utilizes novel magnetic adsorbents. This scheme significantly reduces the preconcentration time and improves the efficiency of analyte determination.
Article
Education & Educational Research
Elaine Stratford, Phillipa Watson, Brett Paull
Summary: This paper presents a research study conducted in an Australian university, exploring the challenges and expectations of early career academics. The findings highlight the need for stronger support and focus on career development within the organizational and sectoral contexts.
Article
Chemistry, Analytical
Harrison Stevens, Estrella Sanz Rodriguez, Brett Paull, Andrew R. Bowie, Zanna Chase, Leon A. Barmuta, Bernadette C. Proemse
Summary: This study presents a simple extraction method for the rapid and selective determination of monosaccharide anhydrides (MAs) concentrations in sediments. MAs detection was performed using ion chromatography with tandem mass spectrometry. The method showed good analytical performance with LODs of 0.10, 0.12, and 0.50 mu g L-1 for LEV, MAN, and GAL, respectively. The developed method was validated using reference materials and successfully applied to quantify MAs in lake sediment samples, allowing the reconstruction of recent fire events.
ANALYTICAL METHODS
(2023)
Article
Chemistry, Analytical
Arushi Manchanda, Vipul Gupta, Liang Wu, Brett Paull
Summary: A new method and platform based on thread-based electrofluidics has been developed for direct transfer, electrophoretic separation, and pre-concentration of swabbed samples. The physicochemical interactions between the analyte, swab, and thread were studied to understand their effect on transfer efficiency. This method has been successfully applied to transfer, separate, and pre-concentrate DNA from blood, as well as directly analyze dried blood samples.
Article
Chemistry, Analytical
Jawairia Umar Khan, Mirbaz Ali Pathan, Sepidar Sayyar, Brett Paull, Peter C. C. Innis
Summary: Electrophoresis on textile fiber substrates allows for the movement, separation, and concentration of charged analytes. Researchers have developed an approach to optimize the experimental conditions affecting the electrophoretic separation on textile-based substrates. By adjusting the electric field magnitude, sample concentration, and sample volume, efficient separation can be achieved without compromising the analysis time on simple and low-cost textile substrates.
ANALYTICAL METHODS
(2023)
Review
Chemistry, Analytical
Vahid Jalili, Abdullah Barkhordari, Brett Paull, Alireza Ghiasvand
Summary: PFAS are a group of fluorocarbon compounds with wide-ranging applications, but their persistence and toxic properties make them a concern in the environment. Their strong C-F bonds make it difficult for chemical or biological mechanisms to break them down. Therefore, sensitive and selective analytical methods are needed to detect and trace PFAS in biological and environmental matrices.
CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
(2023)
Correction
Biochemical Research Methods
Yong Wang, Suhua Yu, Rui Li, Jing Wan, Yuheng Wang, Zongli Huo, Chunyong Wu, Li Mi, Songqin Liu
JOURNAL OF CHROMATOGRAPHY A
(2024)
Review
Biochemical Research Methods
Israel D. Souza, Maria Eugenia C. Queiroz
Summary: Organic-silica hybrid monolithic materials have gained significant attention in separation science and sample preparation due to their unique properties. This review summarizes the characteristics, current status, and recent developments of these materials, as well as discusses synthesis methods, characterization techniques, and strategies for improving extraction efficiency in various applications.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Bhagwat Upreti, Bhanu Prasad Vempatapu, Jagdish Kumar, Pankaj K. Kanaujia
Summary: Lubricating oils are essential for the effective performance of internal combustion engines. This study presents a new HPLC method for determining additives in finished lubricating oils and polar substances in used engine oils.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zongqing Huang, Haoju Hua, Xiuzhen Du, Zipeng Zhen, Wei Zhao, Jun Feng, Ji-an Li
Summary: This study successfully isolated VHHs against the SUMO protein for the first time using biopanning of an immune camelid nanobody library. The VHHs were coupled to agarose resins to form affinity chromatography resins, allowing for one-step purification of various SUMO fusions.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Xueting Qiu, Xuben Hou, Yue Yang, Hao Fang, Fei Cui, Xinying Yang
Summary: In this study, a new method based on electrophoretically mediated microanalysis was developed for the investigation of PTPRO enzymatic activity. The method was successfully used to determine the kinetics of PTPRO and the inhibitory concentration of PTPRO inhibitors. The method exhibited improved accuracy and reduced consumption compared to traditional methods.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Feifei Luo, Mengmeng Hao, Lei Zhang, Yangguo Xie, Wei Hou, Hongya Wang, Zhongli Zhang
Summary: In this study, a comprehensive screening and structure elucidation of 23 nonvolatile organic compounds (NVOCs) in two antibody drugs was conducted. Seven previously unreported compounds were identified. A quantitative method with high sensitivity, accuracy, and precision was developed for evaluating the safety of NVOCs in drug products.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zuzana Vosahlova, Kveta Kalfkova, Martin Gilar, Jakub Szymarek, Maria Mazurkiewicz-Beldzinska, Sylwia Studzi
Summary: A hydrophilic interaction liquid chromatography method was developed for the separation and identification of oligonucleotide impurities and metabolites, and successfully applied to the analysis of serum samples from Spinraza-treated patients.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Aswanidevi Kongasseri, Thirumalai Madhesan, Sangeetha Krishna Kumar, Sushmitha Pedugu Sivaraman, Suchashrita Mitra, Pitchaiah Kancharlapalli Chinaraga, C. V. S. Brahmmananda Rao, Sivaraman Nagarajan, Prabhakaran Deivasigamani, Akhila Maheswari Mohan
Summary: This study focuses on the sequential separation of trivalent lanthanides using modified C-18 silica-packed supports and reversed-phase HPLC technique. By tuning the column modifiers and separation parameters, the researchers achieved systematic separation of Ln(3+). The results showed that the choice of column modifiers and fine-tuning of the modification procedure were crucial for achieving excellent separation.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Raquel Perez-Robles, Szabolcs Fekete, Robert Kormany, Natalia Navas, Davy Guillarme
Summary: There is a mismatch between the sample diluent and the mobile phase in HILIC analysis, leading to analyte breakthrough and peak distortion. Adding a weak solvent for pre-injection can effectively prevent these issues and improve sensitivity.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Oleg Pokrovskiy, Irina Rostovschikova, Konstantin Ustinovich, Ilya Voronov, Dmitry Kosyakov
Summary: A chromatography-like propagation of water through the material bed was observed during supercritical fluid extraction of aroma plants with high moisture content, which could be significant for modeling the kinetics of supercritical fluid extraction of non-volatile compounds.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Yasar Kemal Recepoglu, Ozguer Arar, Asli Yuksel
Summary: Biosorption using phosphorylated hazelnut shell waste (FHS) is a promising method for lithium removal and recovery. This study investigated the performance of a continuous-flow packed-bed column system using FHS for ultra-low level lithium removal. The results showed that the lihium biosorption capacity of the FHS column was unaffected by the bed height, but decreased with increasing flow rate.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Jian Sun, Zheheng Zheng, Zixiao Jia, Jiabin Wang, Xucong Lin
Summary: In this study, an ionic covalent organic framework (iCOF) surface grafting monolithic sorbent was prepared for in-tube solid-phase microextraction (SPME) of aristolochic acids (AAs) in various samples. The density of quaternary ammonium ions in the iCOF was modulated for enhanced adsorption of AAs. The iCOF surface grafting monolithic sorbent was confirmed by different means. Several operating conditions were optimized to develop the online in-tube SPME-HPLC method, which showed good linearity, low limits of detection, and high recoveries for AAs in serum samples. This study presents a feasible approach for the application of COF-based monolithic sorbents in sample preparation.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zeng Wen, Ruihan Peng, Die Gao, Jing Lin, Jia Zeng, Zhou Li, Famin Ke, Zhining Xia, Dandan Wang
Summary: A chitosan-alginate sponge with multiple cross-linking networks was developed for adsorption and enrichment of anionic dyes from food samples. The sponge showed better three-dimensional network structure, mechanical behavior, and stability compared to pure chitosan and alginate sponges. The adsorption performance and selectivity of the sponge were systematically studied, and it maintained high adsorption capacity and selectivity for anionic dyes. The sponge also showed satisfactory reusability and was successfully combined with high-performance liquid chromatography for the enrichment and detection of anionic dyes in candy and cocktail samples.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Hairong Zhang, Xiaojuan Jiang, Dandan Zhang, Yuexin Yang, Qiang Xie, Caisheng Wu
Summary: Analysis of in vivo exposure to traditional Chinese medicine using mass spectrometry is helpful for identifying effective ingredients and developing new drugs. This study focused on Forsythia suspensa (Lian Qiao) and used metabolomics technology to explore its in vivo exposure. By comparing the differences before and after administration, a complete set of nontargeted analysis strategies for TCM exposure was established. The study identified 393 Lian Qiao-related chemical components in mice after administration, including prototypes and metabolites. This study provides a reference for research on the active ingredients of Lian Qiao in vivo.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Oscar Castejon-Musulen, Ricardo Lopez, Ignacio Ontan, Vicente Ferreira
Summary: A quantitative analytical method was developed and validated in this study to determine the concentrations of 81 aroma-relevant wine volatiles. The method utilizes stir bar sorptive extraction and multidimensional gas chromatography with flame ionization detector or mass spectrometer. The method demonstrated good linearity, reproducibility, and recovery, and was successfully applied to analyze 20 wine samples.
JOURNAL OF CHROMATOGRAPHY A
(2024)
