Journal
BIOSYSTEMS
Volume 109, Issue 1, Pages 78-86Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.biosystems.2011.12.006
Keywords
Metabolic P systems; Dynamical systems; Dynamical inverse problems; Stepwise regression
Categories
Ask authors/readers for more resources
MP (Metabolic P) systems are a class of P systems introduced for modelling metabolic processes. We refer to the dynamical inverse problem as the problem of identifying (discrete) mathematical models exhibiting an observed dynamics. In this paper, we complete the definition of the algorithm LGSS (Log-gain Stoichiometric Stepwise regression) introduced in Manca and Marchetti (2011) for solving a general class of dynamical inverse problems. To this aim, we develop a reformulation of the classical stepwise regression in the context of MP systems. We conclude with a short review of two applications of LGSS for discovering the internal regulation logic of two phenomena relevant in systems biology. (C) 2012 Elsevier Ireland Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available