Article
Chemistry, Multidisciplinary
Sara Malekkhaiat Haffner, Elisa Parra-Ortiz, Kathryn L. Browning, Elin Jorgensen, Maximilian W. A. Skoda, Costanza Montis, Xiaomin Li, Debora Berti, Dongyuan Zhao, Martin Malmsten
Summary: The study showed that the topography of nanoparticles strongly influences their interaction with bacteria-mimicking lipid bilayers, especially in the presence of antimicrobial peptides. Virus-like mesoporous nanoparticles exhibit a more pronounced membrane disruption after loading with LL-37 compared to smooth nanoparticles.
Article
Pharmacology & Pharmacy
Jie Zhuang, Yiming Yu, Rui Lu
Summary: Due to abuse of antibiotics, antibiotic resistance has become a global health threat. Many existing antibiotics have lost their effectiveness against drug-resistant bacteria, and the discovery of new antibiotics is becoming increasingly difficult. It is necessary to develop new strategies to combat antibiotic resistance. Nano-drug delivery systems, particularly mesoporous silica nano-particles (MSNs), have been extensively investigated as carriers of antibiotics. MSNs improve the delivery of antibiotics by reducing size, modifying surface, and regulating shapes. Furthermore, MSNs hybridized with metal ions or nanoparticles enhance the antibacterial effect by controlling the release of metal ions or increasing active oxygen species. Metal-capped MSNs can also load antibiotics to exert a synergistic antibacterial effect. This paper reviews the current application of various nanomaterials as antibacterial agents, with a focus on MSNs and approaches for improving their antibacterial effect.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2023)
Article
Engineering, Environmental
Mert Sudagidan, Gulsah Yildiz, Selin Onen, Rabia Al, S. Sevval Nur Temiz, Mediha Nur Zafer Yurt, Behiye Busra Tasbasi, Elif Esma Acar, Aysen Coban, Ali Aydin, Ali D. Dursun, Veli C. Ozalp
Summary: Encapsulation of benzalkonium chloride in mesoporous silica nanoparticles provides an efficient strategy to inhibit microbial activity, specifically targeting Listeria cells while reducing overall concentrations of the disinfectant. This approach allows for significant reduction in disinfectant doses and avoids cytotoxicity to human cells.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Chemistry, Physical
Gabriela Correa Carvalho, Gabriel Davi Marena, Juliana Camila Fischer Karnopp, Juliana Jorge, Rafael Miguel Sabio, Marco Antonio Utrera Martines, Tais Maria Bauab, Marlus Chorilli
Summary: Pharmaceutical nanotechnology has significant advantages in controlling drug release. Mesoporous silica nanoparticles (MSNs) are an important system that can carry and release drugs effectively. However, the use of surfactant CTAB in the synthesis of MSNs may pose toxicity risks.
ADVANCES IN COLLOID AND INTERFACE SCIENCE
(2022)
Article
Biophysics
Sandra Montalvo-Quiros, Sergio Gomez-Grana, Maria Vallet-Regi, Rafael C. Prados-Rosales, Blanca Gonzalez, Jose L. Luque-Garcia
Summary: Tuberculosis remains a major public health issue with a lack of effective vaccine and the emergence of highly antibiotic-resistant strains of Mycobacterium tuberculosis. Silver nanoparticles show high bactericidal efficacy, but their relatively high toxicity calls for the design of nanocarriers for safe delivery. Mesoporous silica nanoparticles have been used as carriers for silver nanoparticles as antimycobacterial agents, demonstrating good capability against Mtb with different synthetic approaches.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Article
Chemistry, Multidisciplinary
Tianyu Li, Efrain E. Rodriguez
Summary: This study demonstrated the hydrothermal conversion of mesoporous TiO2 to mesoporous SrTiO3, with controlled pore size distribution and potential for high-temperature applications due to thermal stability.
CHEMICAL COMMUNICATIONS
(2022)
Review
Nanoscience & Nanotechnology
Didem Sen Karaman, Aysenur Pamukcu, M. Baran Karakaplan, Ozden Kocaoglu, Jessica Rosenholm
Summary: Increased public awareness of infectious diseases due to COVID-19 and antimicrobial resistance has highlighted the urgent need for new and more efficient methods to combat and overcome failures in diagnosis and therapy. A paradigm shift is necessary to prevent future pandemics, with nanomaterials showing great potential in diagnosing bacterial infections.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2021)
Review
Chemistry, Multidisciplinary
Chun Xu, Chang Lei, Yue Wang, Chengzhong Yu
Summary: Dendritic mesoporous silica nanoparticles have attracted attention due to their wide applications, but the terminology used is ambiguous. This review provides a critical analysis of reported dendritic silica nanoparticles according to their structural classification, updating the understanding of their formation mechanisms and the control of structural parameters. The review also focuses on the applications of dendritic mesoporous nanoparticles in the biomedical field, offering new insights into the structure-property relationship.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Review
Chemistry, Inorganic & Nuclear
Neha Benedicta Fernandes, Yogendra Nayak, Sanjay Garg, Usha Y. Nayak
Summary: The field of advanced nanotechnology offers a wide range of nanotheranostics for treating malignant tumors. Among them, Mesoporous Silica Nanoparticles (MSNs) combined with upconversion nanoparticles have gained prominence in biomedicine research due to their remarkable properties in drug targeting, bio-imaging, and photodynamic/photothermal therapy. MSNs have versatile pore sizes, high drug loading efficiency, and can be functionalized to enhance their applicability. This article focuses on MSN-based hybrid nanotheranostics and their designing strategies, characterization, applications, efficacy, limitations, biotoxicity, as well as current challenges and future perspectives.
COORDINATION CHEMISTRY REVIEWS
(2023)
Article
Biochemical Research Methods
Yating Zhang, Buyi Xu, Zehua Wang, Rongji Yang, Leixia Zhu, Wei He, Guoyun Zhou, Jiujuan Li, Jianhui Li, Zhiwei Han, Yan Hong, Shouxu Wang
Summary: In this study, chemical visualization of analytes in fingerprints was achieved using surface-enhanced Raman spectroscopy (SERS) and spray-dispersed gold nanorods (AuNRs). The optimal coverage of AuNRs was determined through theoretical simulations and experimental operations. A rapid sampling method for the chemical of interest was developed by tuning the spray parameters. The SERS imaging of methamphetamine in fingerprint latent was attempted by analyzing the SERS spectral features of methamphetamine. This chemical visualization method provides simultaneous graphical and chemical information of fingerprints, enabling the detection and mapping of methamphetamine at a concentration of 10(-5) M. The data processing approach was improved by employing relevant logical judgments, resulting in enhanced SERS images with sharper fingerprint patterns.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Physical
Chih-Yu Lin, Chia-Min Yang, Mika Linden
Summary: Mesoporous silica nanoparticles (MSN) are potential drug carriers with high drug loading capacity and degradability under biologically relevant conditions. Dissolution studies of MCM-48 MSN in the presence of proteins show that protein concentration affects the kinetics of dissolution and leads to the formation of core-shell structured particles. The results suggest that MSN dissolution kinetics is faster under typical in vitro conditions compared to full serum conditions.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Materials Science, Biomaterials
Marina Martinez-Carmona, Carmela Cela, Vera A. Kuznetsova, Joan A. Geoghegan, Yurii K. Gun'ko
Summary: The research demonstrates that chirality significantly affects the interaction of mesoporous silica nanoparticles with different cells and bacteria at the cellular level. Understanding the role of chirality in nanoparticles is crucial for the advancement of nano-biotechnology.
JOURNAL OF MATERIALS CHEMISTRY B
(2021)
Article
Chemistry, Analytical
Beibei Xie, Zhi-Peng Wang, Ruixue Zhang, Zhen Zhang, Yun He
Summary: This work presents a new method for fabricating Au-NC-NBs with a large specific surface area and high N and Au content, which are used to develop a SERS aptasensor with wider linear range and better selectivity for detecting bacteria. The sensor also performs well in detecting bacteria in real food and biological samples, showing great potential in food safety monitoring and clinical diagnosis.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Applied
Vignesh Krishnan, Joy Sebastian Prakash, Venkatesan Manigandan, G. Devanand Venkatasubbu, Arivalagan Pugazhendhi, Kathirvel Brindhadevi, T. Kalaivani
Summary: This study synthesized mesoporous silicon dioxide nanoparticles with different pore volumes and evaluated their toxicity effects on zebrafish. The results showed that the nanoparticles had excellent drug loading capacity and the survival rate of zebrafish was above 85%.
MICROPOROUS AND MESOPOROUS MATERIALS
(2022)
Review
Biochemistry & Molecular Biology
Razieh Heidari, Vahideh Assadollahi, Pegah Khosravian, Seyed Abbas Mirzaei, Fatemeh Elahian
Summary: The use of nucleic acid to control gene expression is crucial in cancer research, and delivering nucleic acids using nanoparticles has emerged as a safe and efficient system for gene transfer.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Multidisciplinary
Shi-Kung Chen, Kuo-Hsin Chang, Chun-Han Hsu, Zheng-Yi Lim, Fang-Yi Du, Kai-Wen Chang, Mong-Chen Chang, Hong-Ping Lin, Chi-Chang Hu, Chih-Yuan Tang, Ching-Yen Lin
Summary: A new synthetic method for high-performance mesoporous carbon platelets was proposed in this study, suitable for high-power supercapacitors. The composite materials prepared by co-assembly exhibit promising capacitive performance for ultra-high power supercapacitors.
JOURNAL OF THE CHINESE CHEMICAL SOCIETY
(2021)
Article
Chemistry, Physical
Hong-Ping Lin, Ying-Fan Liu, Ying-Xuan Liu, Zi-Xian Yang, Jong-Liang Lin
Summary: Various experimental and theoretical techniques were used to investigate the reaction mechanisms and bonding structures of 3- and 2-bromopropanoic acids on Cu(100) and oxygen-precovered Cu(100). Differences in reaction pathways and products were observed under different conditions.
JOURNAL OF PHYSICAL CHEMISTRY C
(2021)
Editorial Material
Chemistry, Multidisciplinary
Hong-Ping Lin, Jin-Ming Chen
JOURNAL OF THE CHINESE CHEMICAL SOCIETY
(2021)
Article
Energy & Fuels
Jhe-Kai Lin, Cheng-Pao Lee, Hong-Ping Lin, Elbert Halim, Wei-Cheng Wang
Summary: This study focused on the conversion of palm oil into hydro-processed renewable diesel (HRD) using a nonsulfide catalyst. The optimal catalyst (8Ni-8Mo/gamma Al2O3) and conditions for HRD production were determined through experiments, and the fuel components and properties of HRD were analyzed to meet diesel specifications.
INTERNATIONAL JOURNAL OF ENERGY RESEARCH
(2021)
Article
Chemistry, Physical
Hsin-Kai Huang, Yi-Kai Chih, Wei-Hsin Chen, Cheng-Yu Hsu, Kai-Jhei Lin, Hong -Ping Lin, Chun-Han Hsu
Summary: A green template-free method is proposed for the synthesis of mesoporous Ni-Cu/Al2O4 catalyst, which shows excellent catalytic performance and regeneration capability in methanol steam reforming.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2022)
Article
Biochemistry & Molecular Biology
Chun-Han Hsu, Cheng-Han Chung, Tzu-Hsien Hsieh, Hong-Ping Lin
Summary: Multiporous carbons (MPCs) were prepared using ZnO as a template and biomass pyrolysis oil as a carbon source. The characteristics of the prepared MPCs can be controlled by adjusting the ZnO/oil ratio. A sulfur/MPC (S/MPC) composite was prepared by blending sulfur powder with the prepared MPCs and showed promising performance as an electrode material in lithium-ion batteries.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Physical
Kai-Jhei Lin, Yi-Kai Chih, Wei-Hsin Chen, Hsin-Kai Huang, Hong-Ping Lin, Chun-Han Hsu
Summary: In this study, a high surface area mesoporous Cu-Ni/Al2O4 catalyst was synthesized through a simple hydrothermal reconstruction process using low-cost activated alumina. The catalyst exhibited good catalytic performance for hydrogen production via partial oxidation of methanol, while maintaining its stability. The hydrothermal reconstruction method described in this study is facile and can be extended to the preparation of other mesoporous metal-alumina materials for catalyst applications.
Article
Chemistry, Multidisciplinary
Chao-Hui Liu, Ming-Xue Wei, Chun-Han Hsu, Hong-Ping Lin, Yu-Chun Wu
Summary: In this study, SiO2 porous hollow spheres with ultralow refractive index were synthesized using a templating method, allowing for easy control of refractive indices. A droplet coatings method was proposed for displaying distinct structural colors and high angular resolution. Additionally, metal nanoparticles coated on the SPHS surface increased the SERS intensity.
Article
Chemistry, Multidisciplinary
Yu-Chien Ko, Chun-Hsiang Hsu, Chang-An Lo, Chun-Ming Wu, Hung-Ling Yu, Chun-Han Hsu, Hong-Ping Lin, Chung-Yuan Mou, Heng-Liang Wu
Summary: In this study, a low-cost carbon material (XU76 carbon) was synthesized as a sulfur host to address the issues of polysulfide dissolution and shuttle effect in lithium-sulfur batteries. XU76 carbon, with high surface area, good electrical conductivity, and optimized distribution of interconnected micromesopores, efficiently traps polysulfide intermediates and improves sulfur redox kinetics. The sulfur-XU76 carbon cathode exhibits excellent cycling stability and high discharge capacity in experimental tests.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2022)
Article
Chemistry, Multidisciplinary
Chao Hui Liu, Hong Ping Lin
Summary: In this study, nano-sized TiO2/SiO2 cenospheres with a rough surface were successfully synthesized using a designed coating and hydrothermal treatment for application in solar thermal reflective coating. These TSCSs demonstrate significant UVA absorption, high reflectance of visible-IR radiation, and strong scattering of incident light. Additionally, they have good thermal insulation and water resistance.
JOURNAL OF THE CHINESE CHEMICAL SOCIETY
(2022)
Article
Engineering, Chemical
K. P. O. Mahesh, Zi Qin Zhao, Hsiao Yang Liu, Kuan-Ting Lai, Eddie Hsiang-Hua Lai, Hong-Ping Lin, Yu-Chih Chiang
Summary: The study found that using SiO2/MgO/Fe2O3 photocatalyst and low concentration of H2O2 under UVA1 light can effectively degrade dyes and stains, achieving satisfactory teeth whitening without significant impact on the enamel surface. This can be considered as a safe and efficient method for dental bleaching.
JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS
(2022)
Article
Engineering, Environmental
Chih-Feng Wang, Xin-Yu Huang, Hong-Ping Lin, Jem-Kun Chen, Hsieh-Chih Tsai, Wei-Song Hung, Chien-Chieh Hu, Juin-Yih Lai
Summary: The separation of oily wastewater, especially emulsions, is a significant global issue. Researchers have recently focused on sustainable and environmentally friendly materials for the efficient separation of emulsified oil/water mixtures. In this study, superwetting water caltrop shell biochar (WCSB) was prepared and showed excellent separation performance and potential utilitarian applications.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Biochemistry & Molecular Biology
Yu-Hsiang Lu, Yen-Zen Wang, Ming-Ying Tsai, Hong-Ping Lin, Chun-Han Hsu
Summary: The newly prepared benzimidazole-based polyimide (BI-PI) membrane exhibited high thermal stability, reduced pore size, improved mechanical properties, and high specific capacitance, making it a promising separator material for high-performance supercapacitors.
Article
Energy & Fuels
Yi-Kai Chih, Wei-Hsin Chen, Siming You, Chun-Han Hsu, Hong -Ping Lin, Salman Raza Naqvi, Veeramuthu Ashokkumar
Summary: This study aims to develop highly-porous Ni-Cu/Al2O3 catalysts for hydrogen production from the steam reforming of methanol. The impacts of selected operating factors on hydrogen productivity are investigated and the optimal conditions are determined. The results show that the prepared catalysts exhibit superior performance and stability compared to those in the literature.
Article
Chemistry, Multidisciplinary
Guan-Wen Liu, Chen-Shiuan Fan, Chun-Han Hsu, Chia-Hung Hou, Hong-Ping Lin
Summary: A solvent-free ZnO-template method is used to synthesize hierarchical porous carbons, with the micro/meso/macroporous structure controlled by adjusting the amount of ZnO. The synthesized HPCs exhibit high surface area, wide-range pore size distribution, and promising capacitive deionization performances, with HPC-2 showing the highest electrosorption capacity.
Article
Biophysics
Reza Khodadadi, Manouchehr Eghbal, Hamideh Ofoghi, Alireza Balaei, Ali Tamayol, Karen Abrinia, Amir Sanati-Nezhad, Mohamadmahdi Samandari
Summary: This paper introduces an integrated portable centrifugal microfluidic system that automates cell and fluid manipulation for complete blood counting (CBC) analysis at the point-of-care (POC). The system utilizes a specially designed microfluidic disc for cell separation, solution metering and mixing, and cell counting, and is equipped with a custom script for automated quantification of cells. The proposed method shows a strong correlation with the gold standard hematology analyzer for various blood parameters. The portable system offers simplicity, affordability, and low power consumption, making it a potential solution for improving healthcare delivery in resource-limited settings and remote areas.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Nabil H. Bhuiyan, Joon S. Shim
Summary: Developing herd immunity is crucial for changing the course of the COVID-19 pandemic. An AI-driven point-of-care testing platform has been proposed for analyzing the body's response to SARS-CoV-2, and it has been successfully used for quantifying viral proteins and antibodies in blood samples. A data-receptive web-based dashboard system has also been developed for real-time analysis of herd immunity progress.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Alexiane Godain, Timothy M. Vogel, Pascal Fongarland, Naoufel Haddour
Summary: This study provides comprehensive insights into the intricate relationship between shear stress and electroactive biofilms in microbial fuel cells, highlighting the pivotal role of shear stress in influencing the growth kinetics, electrical performance, and physical structure of the biofilms. The study also emphasizes the complexities of extracellular electron transfer mechanisms and the need for complementary metaproteomic analyses.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Linjie Wang, Yixin Chen, Yang Ji, Shujun Zheng, Fei Wang, Caolong Li
Summary: A paper-based biosensor incorporating surface-enhanced Raman spectroscopy (SERS) and colorimetric detection has been developed for efficient quantification of intracellular glutathione (GSH). The biosensor exhibits excellent selectivity, stability, and precision, with low detection limits in both SERS and colorimetric modes. It has been successfully utilized for intracellular GSH detection and validated against a commercial GSH assay kit.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Quan Zhou, Jing Wang, Zhen Zhang, Alain Wuethrich, Richard J. Lobb, Matt Trau
Summary: This study presents a biosensor for sensitive detection of EMT-associated biomarkers on extracellular vesicles (EVs) surfaces during targeted therapy. Through longitudinal monitoring of patients, the biosensor shows its ability to identify the EMT-like phenotype switching on circulating EVs during the development of resistance.
BIOSENSORS & BIOELECTRONICS
(2024)
Review
Biophysics
Pratika Rai, Sabrina N. Hoba, Celine Buchmann, Robert J. Subirana-Slotos, Christian Kersten, Tanja Schirmeister, Kristina Endres, Bernd Bufe, Alexey Tarasov
Summary: Proteases have been proposed as potential biomarkers for various pathological conditions. The development of protease biosensors offers a more efficient way to investigate dysregulated proteases. This review article presents different optical and electrochemical detection methods for designing biosensors for all major protease families.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Chengxin Liu, Xu Shen, Li Yan, Runlian Qu, Yue Wang, Yaqin He, Zixuan Zhan, Piaopiao Chen, Feng Lin
Summary: In this study, a homogeneous rapid electrochemical aptasensor was developed to quantitatively detect CTCs in lung cancer patients. The aptasensor utilized a DNA nanosphere structure and a complementary aptamer to specifically detect mucin 1 as a marker for CTCs. The assay exhibited high specificity and sensitivity, and the results were consistent with other detection methods.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Danni Xue, Xing Dai, Jialong Zhao, Jiayao Zhang, Huan Liu, Kui Liu, Tao Xu, Chenjie Gu, Xingfei Zhou, Tao Jiang
Summary: In this study, a dual-enhancement SERS substrate based on Ti3C2TX and Ag nanocubes was fabricated for precise quantification of ritonavir and ibrutinib in serum. The formation of numerous electromagnetic hotspots between Ag nanocubes facilitated effective photo-induced charge transfer. The composite substrate showed excellent sensitivity, achieving low detection limits and high recoveries, making it promising for monitoring and identification of clinical blood drug concentration.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Tenghua Zhang, Zihui Xie, Xiaohe Zheng, Yuxin Liang, Yao Lu, Hankang Zhong, Feiyang Qian, Yuqing Zhu, Ruiting Sun, Yan Sheng, Jiaming Hu
Summary: This study reports a technology based on cationic lipid-polymer hybrid nanoparticles for efficient extracellular vesicle (EV) enrichment and in-situ detection of internal microRNAs. The technology demonstrates high EV enrichment efficiency and sensitive internal RNA detection, making it potentially useful for early pancreatic cancer diagnosis.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Wenjie Dai, Gaoxu Chen, Xiaoyan Wang, Shujun Zhen, Chengzhi Huang, Lei Zhan, Yuanfang Li
Summary: In this study, a novel metal organic gel (MOG) with dual electrochemiluminescence (ECL) properties was prepared by simple mixing. The MOG exhibited strong and stable anodic and cathodic ECL signals. By utilizing this MOG, an ECL resonance energy transfer (ECL-RET) biosensor was constructed for ultrasensitive detection of a specific gene. The study developed a straightforward technique for obtaining a single luminescent material with dual signals and expanded the analytical application of MOGs in the realm of ECL.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Lais Canniatti Brazaca, Amanda Hikari Imamura, Rodrigo Vieira Blasques, Jessica Rocha Camargo, Bruno Campos Janegitz, Emanuel Carrilho
Summary: The use of microfluidic paper-based analytical devices (muPADs) for medical diagnosis is a growing trend due to their low cost, easy use, simple manufacturing, and potential for application in low-resource settings. This review focuses on the advances in muPADs for medical diagnostics, discussing their use in detecting various biomarkers in common human biofluids. The challenges of biomarker detection in each sample are examined, along with innovative techniques to overcome these limitations. The commercialization difficulties of muPADs are also considered, along with future trends such as wearable devices and integrated platforms.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Minghong Jian, Xudong Sun, Hua Zhang, Xiaotong Li, Shasha Li, Zhenxin Wang
Summary: Matrix metalloproteinases (MMPs) are attractive biomarkers for cancer diagnosis and treatment, but their low abundance in biological samples, especially in the early stages of tumors, makes it challenging to precisely analyze MMP activities. In this study, a peptide microarray-based metal-enhanced fluorescence assay (PMMEFA) is proposed as a sensitive and specific method to simultaneously detect MMP-1, -2, -3, -7, -9, and -13 activities. The PMMEFA showed excellent sensitivity and was capable of detecting MMP activities in various matrices.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Kyung Ho Kim, Eunsu Ryu, Zinah Hilal Khaleel, Sung Eun Seo, Lina Kim, Yong Ho Kim, Hyun Gyu Park, Oh Seok Kwon
Summary: We have developed a novel strategy for discriminative detection of SARS-CoV-2 variants using the plasmonic photothermal effect of gold nanofilms and digital polymerase chain reaction (dPCR) technology. With this method, we were able to detect the delta and omicron variants with high sensitivity within 25 minutes from COVID-19 patients' clinical samples, making it a rapid and accurate point-of-care testing tool.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Zepeng Kang, Yuanming Wang, Haiyan Song, Xueli Wang, Job Zhang, Zhiguang Zhu
Summary: By designing a wearable and flexible lactic-acid/O2 EBFC with an air-breathing biocathode, the limitations of biocathode are effectively solved. The optimal performance conditions are determined through experiments, and the EBFC is successfully applied to power a low-power device.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Huayun Chen, Zhiheng You, Yuhui Hong, Xiao Wang, Mingming Zhao, Yushi Luan, Yibin Ying, Yixian Wang
Summary: This study developed a colorimetric sensor array using gas-responsive two-dimensional metal-organic framework (MOF) composites for highly sensitive detection of volatile organic compounds (VOCs). The dye/Zn-2(bim)(4) composites-based sensor arrays showed enhanced sensitivity and anti-interference properties. The findings demonstrate the potential use of dye/Zn-2(bim)(4) sensor arrays for early perception of plant diseases.
BIOSENSORS & BIOELECTRONICS
(2024)