Annual Research Review: The (epi)genetics of neurodevelopmental disorders in the era of whole-genome sequencing - unveiling the dark matter

A Higher Mutational Burden in Females Supports a “Female Protective Model” in Neurodevelopmental Disorders

(2014) Sébastien Jacquemont et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Editorial: Illuminating the dark matter of developmental neuropsychiatric genetics - strategic focus for future research in child psychology and psychiatry

(2014) Klaus-Peter Lesch   JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY

Synaptic, transcriptional and chromatin genes disrupted in autism

(2014) Silvia De Rubeis et al.   NATURE

Postępy w leczeniu zespołu łamliwego chromosomu X

(2014) Małgorzata Lisik et al.   Neurologia i Neurochirurgia Polska

Autism spectrum disorder severity reflects the average contribution of de novo and familial influences

(2014) Elise B. Robinson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Accounting for genetic and environmental confounds in associations between parent and child characteristics: A systematic review of children-of-twins studies.

(2014) Tom A. McAdams et al.   PSYCHOLOGICAL BULLETIN

Autistic empathy toward autistic others

(2014) Hidetsugu Komeda et al.   Social Cognitive and Affective Neuroscience

Prenatal stress-induced programming of genome-wide promoter DNA methylation in 5-HTT-deficient mice

(2014) K G Schraut et al.   Translational Psychiatry

Microdeletions of 5.5 Mb (4q13.2-q13.3) and 4.1 Mb (7p15.3-p21.1) associated with a saethre-chotzen-like phenotype, severe intellectual disability, and autism

(2013) Shino Shimada et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

The comorbidity of ADHD and autism spectrum disorder

(2013) Kevin M Antshel et al.   Expert Review of Neurotherapeutics

Mapping connectivity in the developing brain

(2013) Emily L. Dennis et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

In Vitro Fertilization and Risk of Autistic Disorder and Mental Retardation

(2013) Marcelle I. Cedars   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Different neurodevelopmental symptoms have a common genetic etiology

(2013) Erik Pettersson et al.   JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY

Resting-State Glutamate and GABA Concentrations Predict Task-Induced Deactivation in the Default Mode Network

(2013) Y. Hu et al.   JOURNAL OF NEUROSCIENCE

Intellectual Disability in Children with Attention Deficit Hyperactivity Disorder

(2013) Alka Ahuja et al.   JOURNAL OF PEDIATRICS

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

(2013)   LANCET

Targeting the endocannabinoid system in the treatment of fragile X syndrome

(2013) Arnau Busquets-Garcia et al.   NATURE MEDICINE

Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutation

(2013) S. Chanda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolutionary History and Genome Organization of DUF1220 Protein Domains

(2013) Majesta S. O’Bleness et al.   G3-Genes Genomes Genetics

Prevalence of attention deficit hyperactivity disorder in primary school children

(2013) JyothsnaAkam Venkata et al.   Indian Journal of Psychiatry

Twins for epigenetic studies of human aging and development

(2012) Qihua Tan et al.   AGEING RESEARCH REVIEWS

The genetic variability and commonality of neurodevelopmental disease

(2012) Bradley P. Coe et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Parental Age and Autism Spectrum Disorders

(2012) Erik Thorlund Parner et al.   ANNALS OF EPIDEMIOLOGY

Family History of Schizophrenia and Bipolar Disorder as Risk Factors for Autism

(2012) Patrick F. Sullivan et al.   ARCHIVES OF GENERAL PSYCHIATRY

Genetic, environmental and stochastic factors in monozygotic twin discordance with a focus on epigenetic differences

(2012) Witold Czyz et al.   BMC Medicine

Impact of the ADHD-susceptibility gene CDH13 on development and function of brain networks

(2012) Olga Rivero et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Dances with black widow spiders: Dysregulation of glutamate signalling enters centre stage in ADHD

(2012) K.P. Lesch et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

The persistence and stability of psychiatric problems in adolescents with autism spectrum disorders

(2012) Emily Simonoff et al.   JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY

The ADHD-susceptibility gene lphn3.1 modulates dopaminergic neuron formation and locomotor activity during zebrafish development

(2012) M Lange et al.   MOLECULAR PSYCHIATRY

Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants

(2012) Wenqing Fu et al.   NATURE

Does microglial dysfunction play a role in autism and Rett syndrome?

(2012) Izumi Maezawa et al.   Neuron Glia Biology

Synaptic Dysfunction in Neurodevelopmental Disorders Associated with Autism and Intellectual Disabilities

(2012) H. Y. Zoghbi et al.   Cold Spring Harbor Perspectives in Biology

Novelty-seeking DRD4 polymorphisms are associated with human migration distance out-of-Africa after controlling for neutral population gene structure

(2011) Luke J. Matthews et al.   AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY

Integrated Genome-Wide Association Study Findings: Identification of a Neurodevelopmental Network for Attention Deficit Hyperactivity Disorder

(2011) Geert Poelmans et al.   AMERICAN JOURNAL OF PSYCHIATRY

Genetic and Epigenetic Networks in Intellectual Disabilities

(2011) Hans van Bokhoven   Annual Review of Genetics

Genetic Heritability and Shared Environmental Factors Among Twin Pairs With Autism

(2011) Joachim Hallmayer   ARCHIVES OF GENERAL PSYCHIATRY

Atypical Prefrontal Connectivity in Attention-Deficit/Hyperactivity Disorder: Pathway to Disease or Pathological End Point?

(2011) Conor Liston et al.   BIOLOGICAL PSYCHIATRY

Clan Genomics and the Complex Architecture of Human Disease

(2011) James R. Lupski et al.   CELL

The Psychiatric Presentation of Fragile X: Evolution of the Diagnosis and Treatment of the Psychiatric Comorbidities of Fragile X Syndrome

(2011) Michael R. Tranfaglia   DEVELOPMENTAL NEUROSCIENCE

A lifetime of attention-deficit/hyperactivity disorder: diagnostic challenges, treatment and neurobiological mechanisms

(2011) Julia Geissler et al.   Expert Review of Neurotherapeutics

CDH13is associated with working memory performance in attention deficit/hyperactivity disorder

(2011) A. Arias-Vásquez et al.   GENES BRAIN AND BEHAVIOR

American College of Medical Genetics standards and guidelines for interpretation and reporting of postnatal constitutional copy number variants

(2011) Hutton M Kearney et al.   GENETICS IN MEDICINE

Case-Control Genome-Wide Association Study of Attention-Deficit/Hyperactivity Disorder

(2011) Benjamin M. Neale et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

Epigenetic regulation of the BDNF gene: implications for psychiatric disorders

(2011) F Boulle et al.   MOLECULAR PSYCHIATRY

The genetics of attention deficit/hyperactivity disorder in adults, a review

(2011) B Franke et al.   MOLECULAR PSYCHIATRY

Multiple Recurrent De Novo CNVs, Including Duplications of the 7q11.23 Williams Syndrome Region, Are Strongly Associated with Autism

(2011) Stephan J. Sanders et al.   NEURON

A Behavioral Comparison of Male and Female Adults with High Functioning Autism Spectrum Conditions

(2011) Meng-Chuan Lai et al.   PLoS One

Differential Effects of Prenatal Stress in 5-Htt Deficient Mice: Towards Molecular Mechanisms of Gene × Environment Interactions

(2011) Daniel Van den Hove et al.   PLoS One

Relative Burden of Large CNVs on a Range of Neurodevelopmental Phenotypes

(2011) Santhosh Girirajan et al.   PLoS Genetics

Epigenetic Transmission of the Impact of Early Stress Across Generations

(2010) Tamara B. Franklin et al.   BIOLOGICAL PSYCHIATRY

Pharmacological reversal of synaptic plasticity deficits in the mouse model of Fragile X syndrome by group II mGluR antagonist or lithium treatment

(2010) Catherine H. Choi et al.   BRAIN RESEARCH

Shared heritability of attention-deficit/hyperactivity disorder and autism spectrum disorder

(2010) Nanda N. J. Rommelse et al.   EUROPEAN CHILD & ADOLESCENT PSYCHIATRY

Genotype–phenotype relationship in three cases with overlapping 19p13.12 microdeletions

(2010) Maria C Bonaglia et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Is the ADHD brain wired differently? A review on structural and functional connectivity in attention deficit hyperactivity disorder

(2010) Kerstin Konrad et al.   HUMAN BRAIN MAPPING

Genome-scan for IQ discrepancy in autism: evidence for loci on chromosomes 10 and 16

(2010) Nicola H. Chapman et al.   HUMAN GENETICS

Prenatal Stress, Glucocorticoids and the Programming of the Brain

(2010) L. A. M. Welberg et al.   JOURNAL OF NEUROENDOCRINOLOGY

A common variant of the latrophilin 3 gene, LPHN3, confers susceptibility to ADHD and predicts effectiveness of stimulant medication

(2010) M Arcos-Burgos et al.   MOLECULAR PSYCHIATRY

Functional impact of global rare copy number variation in autism spectrum disorders

(2010) Dalila Pinto et al.   NATURE

A de novo paradigm for mental retardation

(2010) Lisenka E L M Vissers et al.   NATURE GENETICS

Rate, molecular spectrum, and consequences of human mutation

(2010) M. Lynch   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Not really identical: Epigenetic differences in monozygotic twins and implications for twin studies in psychiatry

(2009) F. Nipa Haque et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Evolutionary Theory of Cancer

(2009) Camille Stephan-Otto Attolini et al.   Annals of the New York Academy of Sciences

Generalist Genes and High Cognitive Abilities

(2009) Claire M. A. Haworth et al.   BEHAVIOR GENETICS

Genetics of psychosis; insights from views across the genome

(2009) Michael C. O’Donovan et al.   HUMAN GENETICS

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

Common genetic variants on 5p14.1 associate with autism spectrum disorders

(2009) Kai Wang et al.   NATURE

Genetic overlap between autism, schizophrenia and bipolar disorder

(2009) Liam S Carroll et al.   Genome Medicine

In What Sense Does ‘Nothing Make Sense Except in the Light of Evolution’?

(2008) Paul Edmund Griffiths   ACTA BIOTHEORETICA

Advanced Parental Age and the Risk of Autism Spectrum Disorder

(2008) M. S. Durkin et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Autism genetics: strategies, challenges, and opportunities

(2008) Brian J. O'Roak et al.   Autism Research

Expression of the GABAergic system in animal models for fragile X syndrome and fragile X associated tremor/ataxia syndrome (FXTAS)

(2008) Charlotte D'Hulst et al.   BRAIN RESEARCH

Reconstructing phylogenies and phenotypes: a molecular view of human evolution

(2008) Brenda J. Bradley   JOURNAL OF ANATOMY

Pre- and peri-natal environmental risks for attention-deficit hyperactivity disorder (ADHD): the potential role of epigenetic processes in mediating susceptibility

(2008) Jonathan Mill et al.   JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY

Evidence for overlapping genetic influences on autistic and ADHD behaviours in a community twin sample

(2008) Angelica Ronald et al.   JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY

Genetic aspects in attention-deficit/hyperactivity disorder

(2008) Ö. Albayrak et al.   JOURNAL OF NEURAL TRANSMISSION

Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies

(2008) Klaus-Peter Lesch et al.   JOURNAL OF NEURAL TRANSMISSION

Role for metabotropic glutamate receptor 5 (mGluR5) in the pathogenesis of fragile X syndrome

(2008) Gül Dölen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Advances in the Treatment of Fragile X Syndrome

(2008) R. J. Hagerman et al.   PEDIATRICS

Rare Structural Variants Disrupt Multiple Genes in Neurodevelopmental Pathways in Schizophrenia

(2008) T. Walsh et al.   SCIENCE