Article
Environmental Sciences
Wenting Wang, In-Seok Lee, Jeong-Eun Oh
Summary: This study investigated the occurrence and distribution of benzotriazole UV stabilizers and UV filters in marine environments in South Korea. The findings suggest that these substances can transfer through the marine food web, with some showing the ability to bioaccumulate and biomagnify.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Sarah Montesdeoca-Esponda, Maria Esther Torres-Padron, Zoraida Sosa-Ferrera, Jose Juan Santana-Rodriguez
Summary: Tourism is a significant economic sector globally, but its impact on coastal areas, particularly in relation to personal care products such as UV filters and stabilizers, can lead to pollution issues. This study focused on assessing the presence and exposure of organic UV filters and stabilizers in Gran Canaria Island to draw conclusions for similar regions. The research highlighted the importance of understanding the distribution of these pollutants in different matrices for environmental managers in coastal areas reliant on tourism.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Engineering, Environmental
Pengyang Li, Wenyuan Su, Wenqing Liang, Bao Zhu, Tingyu Li, Ting Ruan, Guibin Jiang
Summary: This study comprehensively explored the temporal trends of benzotriazole UV stabilizers (BZT-UVs) in mollusks collected from the Chinese Bohai Sea between 2010 and 2018 using a combination of target, suspect, and nontarget screening analysis. Significant residue levels of the target analytes were found, with a gradual decrease in total concentrations of BZT-UVs. The relative abundance of UV-327 increased during the study period.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Chemistry, Analytical
Georgia Sidiropoulou, Abuzar Kabir, Kenneth G. Furton, Fotini S. Kika, Konstantinos Fytianos, Paraskevas D. Tzanavaras, Constantinos K. Zacharis
Summary: In this study, fabric phase sorptive extraction was successfully used for the rapid isolation of selected antiviral drugs from human urine. The optimized method showed high efficiency, speed, and promising clinical applications.
MICROCHEMICAL JOURNAL
(2022)
Article
Environmental Sciences
Yuuta Sakuragi, Hideshige Takada, Hiroya Sato, Atsuhito Kubota, Masaru Terasaki, Shinji Takeuchi, Atsuko Ikeda-Araki, Yoko Watanabe, Shigeyuki Kitamura, Hiroyuki Kojima
Summary: This study measured the concentrations of nine representative BUVSs in plastic bottle caps, food packages, and plastic shopping bags purchased from Japanese grocery stores, and found that eight BUVSs were detected in these plastic products, with UV-P and UV-326 detected in all bottle caps at relatively high concentrations. Additionally, the study characterized the agonistic and/or antagonistic activities of 13 BUVSs against human estrogen receptors and androgen receptor, revealing potential endocrine-disrupting effects.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Engineering, Environmental
Wan Chan, Long Jin, Zhihan Sun, Stephen M. Griffith, Jian Zhen Yu
Summary: The study demonstrates the feasibility of using ordinary face masks for sampling airborne PAHs, with the method proving to be quantitative and applicable in various indoor and outdoor environments. The new method, which is simple, convenient, and cost-effective, can track PAH concentrations down to the individual level, showing great potential for routine occupational exposure monitoring and large-scale surveillance.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2021)
Article
Environmental Sciences
Atsuhito Kubota, Masaru Terasaki, Yuuta Sakuragi, Ryuta Muromoto, Atsuko Ikeda-Araki, Hideshige Takada, Hiroyuki Kojima
Summary: This study found that some benzotriazole UV stabilizers (BUVSs) induce the differentiation of regulatory T cells (Tregs) through the activation of the aryl hydrocarbon receptor (AhR), functioning as immunosuppressive modulators.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Engineering, Environmental
Sen He, Han Xiao, Shuang Luo, Xin Li, Jia-Da Zhang, Xiao-Min Ren, Yuan Yang, Xian-De Xie, Yao-Yu Zhou, Yu-Long Yin, Lin Luo, Lin-Ying Cao
Summary: This study reveals the potential disruption mechanism of benzotriazole ultraviolet stabilizers (BUVSs) through estrogen-related receptors alpha and gamma (ERR alpha and ERR gamma) pathways. BUVSs were found to bind to ERR gamma ligand binding domain (ERR gamma-LBD) and promote the transcriptional activities of ERR alpha and ERR gamma. Molecular dynamics simulation showed that BUVSs had lower binding free energy with ERR gamma than with ERR alpha. The structure-activity relationship analysis revealed the key structural factors impacting the binding of BUVSs with ERR gamma.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Chemistry, Analytical
Liga Lauberte, Jevgenija Ponomarenko, Alexander Arshanitsa
Summary: An experimentally proven chromatographic analysis method was established for the analysis of diarylheptanoids in grey alder and black alder bark. The combination of a photodiode array detector and a high-resolution mass spectrometer was found to be the most effective for comprehensive analysis of multicomponent extracts. Sixteen different diarylheptanoids were successfully identified and semi-quantified in the alder bark extracts. This method provides a reliable tool for the identification and quality control of diarylheptanoids in Alnus species extracts.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2022)
Article
Chemistry, Analytical
Dandan Gong, Manhuayun Zhai, Fangliang Yang, Guoxiang Sun, Hong Zhang
Summary: A fast, selective and sensitive UHPLC-MS/MS method was developed to determine the bioactive components in Compound liquorice tablets and investigate their pharmacokinetics in rats. The results showed synergistic effects between Licorice Extract and Powered Poppy Capsule Extractive, prolonging the efficacy of the tablets. Integrated pharmacokinetics provided a comprehensive understanding of the relationship between the pharmacokinetic behaviors of herbal medicine.
MICROCHEMICAL JOURNAL
(2021)
Article
Environmental Sciences
Megan Carve, Navneet Singh, Matthew Askeland, Graeme Allinson, Jeff Shimeta
Summary: This study developed a SALLE-LC-MS/MS method for simultaneous extraction, separation, and quantification of organic UV filters (OUVFs) in water. The presence of OUVFs in river and seawater samples collected in and near Port Phillip Bay, Australia was investigated. The concentrations of OUVFs varied over time and were influenced by recreational activities and water residence time.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Dariusz Kiejza, Joanna Karpinska, Urszula Kotowska
Summary: Benzotriazole UV stabilizers (BUVs) are widely used for their UV absorption properties but have adverse effects on the environment and living organisms. This study explores the chemical oxidation of five UV filters from the benzotriazole group using peracetic acid and metal ions, revealing first order kinetics and oxidation mechanisms of the compounds.
Article
Chemistry, Analytical
Qiulin Zhang, Linna You, Beibei Chen, Man He, Bin Hu
Summary: Utilizing porous nickel foam as carrier, a stir bar coated with reduced graphene oxide was successfully prepared for improved extraction efficiency of benzotriazole compounds. A new analytical method combining SBSE and HPLC-DAD was established with low detection limits and a wide linear range for the determination of benzotriazole compounds in environmental water samples.
Article
Chemistry, Multidisciplinary
Liang Fei, Zhao-Yang Zhang, Yongsong Tan, Ting Ye, Dongfang Dong, Yunjie Yin, Tao Li, Chaoxia Wang
Summary: Researchers have developed an efficient and robust wearable solar thermal management material using azopyrazole-containing microcapsules with a deep-UV-filter shell. The material can co-harvest and store solar and thermal energy, achieving efficient photocharging and photo-discharging, high energy density, and long-term storage sustainability. It can also withstand multiple cycles of washing, rubbing, and recharging without significant loss of energy-storage capacity, offering a promising route for personal thermal management applications.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Analytical
Sergio Santana-Viera, Alejandro Canino-Byreing, Maria Esther Torres-Padron, Zoraida Sosa-Ferrera, Jose Juan Santana-Rodriguez, Abuzar Kabir, Kenneth G. Furton
Summary: An efficient and sensitive method using FPSE and UHPLC-FD has been developed for the extraction and analysis of anthracyclines from sewage samples. The method shows satisfactory reproducibility and low detection limits, and avoids the common matrix effect issues.
Article
Biochemistry & Molecular Biology
Bharti Jain, Rajeev Jain, Prashant Kumar Jaiswal, Torki Zughaibi, Tanvi Sharma, Abuzar Kabir, Ritu Singh, Shweta Sharma
Summary: A green, fast, high-sample-throughput, non-instrumental, and affordable analytical method based on surfactant-assisted dispersive liquid-liquid microextraction (SA-DLLME) combined with thin-layer chromatography-digital image colourimetry (TLC-DIC) was proposed for determining favipiravir in biological and pharmaceutical samples. The method showed good linear range, low LOD and LOQ, and close agreement with HPLC-UV analysis results. The proposed methodology is green in nature and can be applied in resource-limited laboratories during the COVID-19 pandemic.
Article
Food Science & Technology
Oscar Castro, Silvia Borrull, Jordi Riu, Sandra Gimeno-Monforte, Sarah Montesdeoca-Esponda, Zoraida Sosa-Ferrera, Jose Juan Santana-Rodriguez, Eva Pocurull, Francesc Borrull
Summary: Seafood, although beneficial for health, may pose potential risks due to the presence of chemical compounds such as HPVs. A study was conducted in Catalonia and the Canary Islands, Spain, to assess the occurrence of HPVs in commonly consumed seafood species and estimate the associated exposure and risk. Results showed higher levels of HPVs in Catalonia samples, with phthalate esters and benzenesulfonamides being the predominant compounds. Multivariate analysis revealed spatial differences in HPVs concentration profiles between Catalonia and the Canary Islands. Although exposures were higher in Catalonia, the intake of HPVs via seafood was not a major concern in either location.
FOOD AND CHEMICAL TOXICOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Cristian D'Ovidio, Marcello Locatelli, Miryam Perrucci, Luigi Ciriolo, Kenneth G. Furton, Isil Gazioglu, Abuzar Kabir, Giuseppe Maria Merone, Ugo de Grazia, Imran Ali, Antonio Maria Catena, Michele Treglia, Luigi T. Marsella, Fabio Savini
Summary: LC-MS/MS plays a crucial role in screening and tracking pharmacotoxicological and forensic cases due to its advanced features. This review paper focuses on its applications in pharmacotoxicology and highlights its importance in the development of pharmacological and forensic research. It discusses therapeutic drug monitoring and clinical approaches as well as the determination of illicit drugs.
Article
Environmental Sciences
Emily Gonzalez-Bareiro, Sarah Montesdeoca-Esponda, Jesus De la Fuente, Zoraida Sosa-Ferrera, Manuel Arbelo, Antonio Fernandez, Jose Juan Santana-Rodriguez
Summary: The presence of UVFs and UVSs in common bottlenose dolphins was evaluated for the first time. These compounds, found in personal care products, have unknown effects on the environment. The study aimed to assess the pollution to dolphins due to human activity by determining the presence of 12 UVFs and UVSs in their blubber samples. Three compounds were detected in multiple samples, with OC being present in all samples at the highest concentration.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Chemistry, Analytical
Anastasia Korpeti, Natalia Manousi, Abuzar Kabir, Kenneth G. Furton, Paraskevas D. Tzanavaras, Constantinos K. Zacharis
Summary: In this study, a simple and rapid method combining fabric phase sorptive extraction (FPSE) and high performance liquid chromatography-ultraviolet detection (HPLC-UV) was developed for monitoring salivary vitamin B12 levels. Sol-gel Carbowax 20M coated polyester membranes were chosen for the selective extraction of the target analyte. The method showed good precision with a relative standard deviation better than 8.2% and the sol-gel Carbowax 20M coated FPSE membranes were found to be reusable for up to 25 times.
Article
Chemistry, Analytical
Alberto Moral, Francesc Borrull, Kenneth G. Fourton, Abuzar Kabir, Rosa Maria Marce, Nuria Fontanals
Summary: A novel sol-gel silica-based mixed-mode zwitterionic sorbent modified with graphene microparticles was synthesized, which exhibited high retention in the solid-phase extraction (SPE) of benzothiazoles, benzotriazoles and benzenesulfonamides due to the multiple functional groups and graphene microparticles.
Article
Medicine, General & Internal
Janet Crespo-Cajigas, Vidia A. A. Gokool, Andrea Ramirez Torres, Liam Forsythe, Benjamin S. S. Abella, Howard K. K. Holness, Alan T. Charlie Johnson, Richard Postrel, Kenneth G. G. Furton
Summary: Since the outbreak of the COVID-19 pandemic, there has been significant interest in developing rapid detection measures. This study explored the use of hand odor samples and analytical instrumentation to detect SARS-CoV-2-infected individuals. By analyzing volatile organic compounds (VOCs) extracted from hand odor samples, predictive models were developed using sparse partial least squares discriminant analysis. The research highlights the potential of using odor signatures as a diagnostic tool and lays the foundation for optimizing other rapid screening sensors.
Article
Chemistry, Analytical
Georgios Antoniou, Vasileios Alampanos, Abuzar Kabir, Torki Zughaibi, Kenneth G. Furton, Victoria Samanidou
Summary: This study presents a method for the simultaneous determination of four resin monomers in human urine using magnet integrated fabric phase sorptive extraction (MI-FPSE) and high performance liquid chromatography (HPLC) diode array detection (HPLC-DAD). MI-FPSE is a novel configuration of FPSE that enhances the extraction kinetic factor. The method was validated for its linearity, selectivity, accuracy, precision, and stability, and showed good performance in the analysis of real urine samples.
Article
Environmental Sciences
Alicia Herrera, Andrea Acosta-Dacal, Octavio Perez-Luzardo, Ico Martinez, Jorge Rapp, Stefanie Reinold, Sarah Montesdeoca-Esponda, Daniel Montero, May Gomez
Summary: Microplastic pollution and associated chemical contaminants in marine organisms are a growing concern. This study examines the trophic transfer and biomagnification of three chemical pollutants found in microplastics. It was found that these pollutants were transferred from the feed to the muscle and liver of fish, even when microplastics with different levels of contamination were present. However, no effects on fish condition indices were observed.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Spectroscopy
S. K. Manirul Haque, Abuzar Kabir, Nafisur Rahman, Syed Najmul Hejaz Azmi
Summary: The high-performance liquid chromatographic (HPLC) and kinetic spectrophotometric methods were established for the determination of valsartan (VAL) in pharmaceutical formulations. The spectrophotometric procedures utilized different strategies to evaluate the VAL content, and the HPLC procedure was optimized using response surface methodology (RSM) and Box-Behnken design (BBD). Both methods showed excellent accuracy and precision, and were validated according to International Conference on Harmonization (ICH) guidelines. The analytical Eco-Scale score demonstrated that these green methods were a better option for VAL quantification.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Engineering, Environmental
Maria dos Anjos de Jesus Barros Monteiro Lopes, Rayco Guedes-Alonso, Vanessa Mendoza-Grimon, Sarah Montesdeoca-Esponda, Juan Ramon Fernandez-Vera, Zoraida Sosa-Ferrera, Jose Juan Santana-Rodriguez, Maria del Pino Palacios-Diaz
Summary: The purpose of this study is to monitor the quality of treated water in Cape Verde to ensure its safety and sustainability for reuse. The study found that most pharmaceutical compounds had similar removal efficiencies in two natural wastewater treatment plants, with only carbamazepine concentrations increasing in effluents. With proper design and management, these treatment plants can produce water that meets irrigation water quality standards.
Article
Chemistry, Analytical
Ana Castineira-Landeira, Lua Vazquez, Antonia M. Carro, Maria Celeiro, Abuzar Kabir, Kenneth G. Furton, Thierry Dagnac, Maria Llompart
Summary: A rapid sample preparation FPSE method coupled with GC-MS/MS was developed to determine synthetic musks in environmental water and wastewater. The method showed high accuracy and precision, and allowed quantitative analysis without repeating the extraction step.
MICROCHEMICAL JOURNAL
(2024)
Article
Environmental Sciences
Antonio Ferracane, Natalia Manousi, Abuzar Kabir, Kenneth G. Furton, Alice Mondello, Peter Q. Tranchida, George A. Zachariadis, Victoria F. Samanidou, Luigi Mondello, Erwin Rosenberg
Summary: Magnet-integrated fabric phase sorptive extraction (MI-FPSE) is a powerful sample preparation technique for environmental analysis, which allows for the extraction of various pesticides without the need for sample pretreatment. It has been demonstrated that dual sol-gel sorbents in the MI-FPSE devices provide better extraction efficiency and recovery compared to single-materials devices. The proposed method shows great potential for multi-class analysis of environmental surface water samples.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Chemistry, Applied
Bharti Jain, Rajeev Jain, Abuzar Kabir, Torki Zughaibi, Atul Bajaj, Shweta Sharma
Summary: This article presents a rapid, sustainable, highly efficient, and miniaturized protocol for the identification and quantification of three sedative-hypnotic drugs in alcoholic beverages and complex food samples using fabric phase sorptive extraction and gas chromatography-mass spectrometry. The method displayed good linearity, detection limits, and precision after optimization, making it effective for determining drug-facilitated crimes in forensic food samples.