Article
Cell Biology
Prateep Amonruttanapun, Sukumal Chongthammakun, Siriporn Chamniansawat
Summary: The activation of microglia may be induced by the neurotoxicity of neurons, potentially contributing to the pathogenesis of AD. Although OA did not show cytotoxicity towards microglial cells, it may affect their function by increasing the expression of Iba1. Cells treated with OA-induced SH-SY5Y cells showed increased tau hyperphosphorylation, indicating a potential toxic role of OA in microglia in AD.
CELL BIOLOGY INTERNATIONAL
(2022)
Article
Biochemistry & Molecular Biology
Anuradha Venkatramani, Sandipan Mukherjee, Anuradha Kumari, Dulal Panda
Summary: The natural naphthoquinone shikonin can impede the aggregation and fibrillization of tau protein, reducing the size of tau aggregates and inhibiting the formation of tau filaments. It also protects neuroblastoma cells from toxicity induced by tau aggregates. Shikonin shows promise as a potential therapeutic agent for tauopathies.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Biochemistry & Molecular Biology
Yuchen Sun, Joseph Bressler
Summary: Ethyl Maltol (EM) is a commonly used flavoring compound that can bind iron and facilitate iron transport. This study found that EM disrupts intracellular iron homeostasis by increasing the labile iron pool and iron-responsive protein activity. EM also affects the expression of iron-responsive genes and leads to decreased cell viability and increased DNA damage through the p53 pathway. The effects of EM on iron homeostasis are attenuated by the expression of amyloid precursor protein (APP).
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
(2023)
Article
Multidisciplinary Sciences
Sivaprakasam R. Saroja, Kirill Gorbachev, T. C. W. Julia, Alison M. Goate, Ana C. Pereira
Summary: A protein called glypican-4 (GPC-4) secreted by astrocytes is shown to drive tau hyperphosphorylation induced by APOE4, a genetic risk factor for Alzheimer's disease. This discovery provides insights into the mechanisms underlying tauopathies and highlights the role of GPC-4 in tau accumulation and propagation.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Nutrition & Dietetics
Aitor Blanco-Miguez, Hector Tames, Patricia Ruas-Madiedo, Borja Sanchez
Summary: This study presents evidence of A beta-like peptides released from the gut microbiome, with one peptide inducing pathways related to Alzheimer's disease in neuron cell-line model. It opens new approaches for understanding the relationship between gut microbiota and AD, suggesting potential implications for targeted microbiota modification in animal models to study the role of gut bacteria in this progressive disease.
Article
Biochemistry & Molecular Biology
Thomas S. Webberley, Ryan J. Bevan, Joshua Kerry-Smith, Jordanna Dally, Daryn R. Michael, Sophie Thomas, Meg Rees, James E. Morgan, Julian R. Marchesi, Mark A. Good, Sue F. Plummer, Duolao Wang, Timothy R. Hughes
Summary: This study assessed the neuroprotective potential of the Lab4P probiotic consortium in aging and metabolic syndrome-associated neurodegenerative pathologies. The results showed that supplementation with probiotics prevented cognitive decline, hippocampal neuron deterioration, and inflammation in mice. In human cell culture models, probiotic metabolites demonstrated a neuroprotective capability against beta-amyloid challenge. Overall, these findings suggest that Lab4P has the potential to be a neuroprotective agent and support further research in other neurodegenerative conditions in animal models and human studies.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Clinical Neurology
Elaine W. L. Chan, Emilia T. Y. Yeo, Kelly W. L. Wong, Mun L. See, Ka Y. Wong, Jeremy K. Y. Yap, Sook Y. Gan
Summary: Piper sarmentosum Roxb. (PS) has neuroprotective properties against A beta-induced neurotoxicity, potentially through the regulation of amyloidogenesis and reduction of phosphorylated tau levels. Further studies are needed to fully understand the mechanism of action and its potential as a therapeutic agent for Alzheimer's disease.
CURRENT ALZHEIMER RESEARCH
(2021)
Article
Multidisciplinary Sciences
Daniel Giovinazzo, Biljana Bursac, Juan Sbodio, Sumedha Nalluru, Thibaut Vignane, Adele M. Snowman, Lauren M. Albacarys, Thomas W. Sedlak, Roberta Torregrossa, Matthew Whiteman, Milos R. Filipovic, Solomon H. Snyder, Bindu D. Paul
Summary: Alzheimer's disease is characterized by memory, executive, and motor function deterioration, with neuropathological hallmarks including neurofibrillary tangles, paired helical filaments, and amyloid plaques. Dysregulation of signaling by hydrogen sulfide has been shown during aging and may play a role in preventing hyperphosphorylation of Tau in Alzheimer's disease. Furthermore, administering the H2S donor sodium GYY4137 to mouse models of Alzheimer's disease has been shown to ameliorate motor and cognitive deficits associated with the disease.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Biochemistry & Molecular Biology
Ching-Hsuan Chou, Chia-Ron Yang
Summary: Evodiamine significantly reduces phosphorylated tau expression, reduces tau aggregation and neuronal cell death. Evodiamine exhibits neuroprotective effects by inhibiting glycogen synthase kinase 3 beta, cyclin-dependent kinase 5, and mitogen-activated protein kinase pathways.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biochemistry & Molecular Biology
Zihan Qi, Ying Zhang, Kai Yao, Mengqi Zhang, Yixuan Xu, Jianfeng Zhang, Xiaojing Bai, Hengbing Zu
Summary: Downregulation of DHCR24 may be associated with the pathogenesis of AD, affecting tau protein phosphorylation and cholesterol synthesis, as demonstrated in a novel lipid raft-dependent PP2A signaling pathway.
NEUROCHEMICAL RESEARCH
(2021)
Article
Geriatrics & Gerontology
Ni-Ni Chiang, Te-Hsien Lin, Yu-Shan Teng, Ying-Chieh Sun, Kuo-Hsuan Chang, Chung-Yin Lin, Hsiu Mei Hsieh-Li, Ming-Tsan Su, Chiung-Mei Chen, Guey-Jen Lee-Chen
Summary: This study evaluated the Tau aggregation inhibitory activity and neuroprotection of four natural flavones in SH-SY5Y neuroblastoma cells. Among them, 7,8-DHF, quercetin, and apigenin showed promising results in reducing Tau aggregation, oxidative stress, and promoting neurite outgrowth. The neuroprotective effects of these flavones were mediated through HSPB1, NRF2, and TRKB pathways, providing new potential treatment strategies for Alzheimer's disease.
FRONTIERS IN AGING NEUROSCIENCE
(2021)
Article
Cell Biology
Claudia Magrin, Martina Bellafante, Martina Sola, Ester Piovesana, Marco Bolis, Luciano Cascione, Sara Napoli, Andrea Rinaldi, Stephanie Papin, Paolo Paganetti
Summary: In this study, we performed a bioinformatics analysis to better understand the possible role of Tau in regulation of chromatin compaction and gene expression. Our findings suggest that Tau depletion leads to deregulation of transcripts involved in the polycomb repressive complex 2, leading to decreased levels of core components of the complex and lower histone 3 trimethylation. These changes are associated with increased senescence induction in Tau-deficient cells.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Andrila E. Collins, Tarek M. Saleh, Bettina E. Kalisch
Summary: This study aimed to assess the cytoprotective effects of the novel antioxidant compound VANL-100 in a cellular model of beta-amyloid (A beta)-induced toxicity. The results demonstrate that VANL-100 significantly attenuated A beta-induced cell death, indicating its cytoprotective effects against A beta-induced toxicity.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Cell & Tissue Engineering
Lijuan Huang, Hao Wang, Haijuan Sui, Yijie Shi, Liang Zhao
Summary: Circulating plasma exosomes (Pla-Exo) enriched with multiple microRNAs (miRNAs) play a crucial role as biomarkers in clinical diagnosis or therapeutic applications. Research has shown that Pla-Exo can cross the blood-brain barrier and ameliorate cognitive dysfunction in Alzheimer's disease mice.
JOURNAL OF BIOMATERIALS AND TISSUE ENGINEERING
(2021)
Article
Biochemistry & Molecular Biology
Keren Zohar, Elyad Lezmi, Tsiona Eliyahu, Michal Linial
Summary: The compound ladostigil has been shown to alleviate cell damage induced by oxidation, inhibit microglial activation, and improve learning deficits under conditions of chronic oxidative stress in the aging brain.
Article
Biophysics
Diana Seidel, Rebecca Rothe, Mandy Kirsten, Heinz-Georg Jahnke, Konstantin Dumann, Mirjana Ziemer, Jan-Christoph Simon, Andrea A. Robitzki
BIOSENSORS & BIOELECTRONICS
(2019)
Article
Biophysics
Heinz-Georg Jahnke, Sabine Schmidt, Ronny Frank, Winnie Weigel, Christoph Proennecke, Andrea A. Robitzki
BIOSENSORS & BIOELECTRONICS
(2019)
Article
Biochemistry & Molecular Biology
Alice Abend, Chelsie Steele, Sabine Schmidt, Ronny Frank, Heinz-Georg Jahnke, Mareike Zink
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2020)
Article
Chemistry, Multidisciplinary
Christian Sonnendecker, Juliane Oeser, P. Konstantin Richter, Patrick Hille, Ziyue Zhao, Cornelius Fischer, Holger Lippold, Paula Blazquez-Sanchez, Felipe Engelberger, Cesar A. Ramirez-Sarmiento, Thorsten Oeser, Yuliia Lihanova, Ronny Frank, Heinz-Georg Jahnke, Susan Billig, Bernd Abel, Norbert Straeter, Joerg Matysik, Wolfgang Zimmermann
Summary: Enzyme-based hydrolysis is a promising strategy for sustainable recycling of plastics. A study found that the enzyme PHL7 can completely degrade plastics and the products can be used to synthesize new plastics.
Article
Biochemistry & Molecular Biology
Alice Abend, Chelsie Steele, Heinz-Georg Jahnke, Mareike Zink
Summary: Cell-material interactions are crucial for biomedical applications, impacting cell survival and behavior both in vitro and in vivo. Neurons and glial cells exhibit different adhesion and spreading characteristics on various culture materials, with TiN and nanocolumnar TiN supporting better neuronal growth. The designed nanocolumnar TiN also shows potential for building miniaturized microelectrode arrays for impedance spectroscopy.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Nanoscience & Nanotechnology
Sabine Schmidt, Tobias Haensch, Ronny Frank, Heinz-Georg Jahnke, Andrea A. Robitzki
Summary: In this study, a silicon nitride (SiN) passivation was established by physical vapor deposition (PVD) and evaluated for impedance spectroscopy-based monitoring of cells. The findings showed that SiN is a suitable alternative passivation, with significantly higher cell signals observed on microelectrodes larger than 50 μm in diameter. Additionally, the SiN passivation layer demonstrated high compatibility for bonding with PEGDA and PDMS microfluidic structures without any leakage.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Physical
Ronny Frank, Dana Krinke, Christian Sonnendecker, Wolfgang Zimmermann, Heinz-Georg Jahnke
Summary: The Earth has entered the Anthropocene, characterized by widespread environmental pollution from plastics like PET. There is a pressing need for ecofriendly and cost-effective solutions for plastic recycling and reuse. By altering the dielectric properties of PET films, a monitoring system has been developed using impedance spectroscopy to analyze the enzymatic hydrolysis process of PET films with polyester hydrolases.
Article
Biotechnology & Applied Microbiology
Anne Kuchenbuch, Ronny Frank, Jose Vazquez Ramos, Heinz-Georg Jahnke, Falk Harnisch
Summary: This study introduces a new electrochemical microwell plate for investigating the electrochemical and metabolic properties of electroactive microorganisms, allowing for experiments in both pure culture and co-culture modes. Results show that different electron donors have an impact on current density and coulombic efficiency, and the microbial electrochemical performance is correlated with the shift in microbial relative abundance.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Biophysics
Sabine Schmidt, Ronny Frank, Dana Krinke, Heinz-Georg Jahnke, Andrea A. Robitzki
Summary: Microelectrode arrays (MEA) are widely used for bioelectronic monitoring. In this study, we explored the use of a polymer-based substrate, PMMA, as an alternative to glass substrates. After optimizing the structuring process, we achieved a comparable resolution and integrated multiple vias into the substrate for easy contacting. We validated the performance of our PMMA MEA through different bioelectronic monitoring techniques.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Biophysics
Franziska D. Zitzmann, Sabine Schmidt, Max Naumann, Detlev Belder, Heinz-Georg Jahnke, Andrea A. Robitzki
Summary: Three-dimensional cell models are preferred for in vitro studies as they closely resemble the native in vivo situation. To meet the demand for noninvasive and label-free methods for analyzing three-dimensional cultures, impedance spectroscopy combined with microcavity arrays (MCAs) is desirable. In this study, we used selective laser etching to fabricate microcavities in fused silica and borosilicate glass, overcoming the limitations of the previous MCA. Our SLE-fabricated MCAs with variable base and central cone electrode improve the bioelectronic analyses of cellular changes in heterogeneous 3D models.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Chemistry, Analytical
Ronny Frank, Jose Vazquez Ramos, Ronny Azendorf, Christoph Proennecke, Sabine Schmidt, Heinz-Georg Jahnke, Andrea A. Robitzki
Summary: Simultaneous optical and electrochemical measurements are advantageous for biosensor technology. Researchers have developed an electrochemical-optical 96-well microplate to track the bioelectrocatalysis process in real-time. The combination of fluorometric and chronoamperometric measurements allows for unbiased quantitative determination of enzymatic products and monitoring of enzyme activity.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Dermatology
Katrin Rietscher, Heinz-Georg Jahnke, Matthias Ruebsam, Eric W. Lin, Cristina Has, M. Bishr Omary, Carien M. Niessen, Thomas M. Magin
Summary: This study demonstrates that the multikinase inhibitor PKC412 can reduce keratin aggregation in patient-derived EBS keratinocytes and restore intercellular adhesion. The findings provide a proof of concept for the repurposing of existing drugs for the targeted treatment of EBS and pave the way for clinical trials using PKC412 in EBS patients.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Tobias Haensch, Franziska D. Zitzmann, Heinz-Georg Jahnke, Maximilian E. Blaha, Erik Paternoga, Kirsten Zeitler, Detlev Belder, Andrea A. Robitzki
Summary: This article introduces the miniaturization and integration of chemical reactions into fluidic systems to reduce solvent and reactant usage while increasing synthesis efficiency. Real-time, label-free monitoring is achieved through electrochemical impedance spectroscopy. The optimization of electrode structures in microfluidic channels allows for sensitive detection and quantification of compounds like propranolol. The integrated electrodes also enable the monitoring and control of fluidic flows for purification processes during free-flow electrophoresis.
Article
Materials Science, Biomaterials
Alice Abend, Chelsie Steele, Sabine Schmidt, Ronny Frank, Heinz-Georg Jahnke, Mareike Zink
Summary: Lab-on-a-chip devices offer advantages in studying biological cells, but realistic cell organization is important. A co-culture system of neuron-like and glial-like cells can model different brain regions. Nanocolumnar TiN has improved properties for biocompatibility and neural recording.
BIOMATERIALS SCIENCE
(2022)
Article
Biochemical Research Methods
Ronny Frank, Christoph Proennecke, Ronny Azendorf, Heinz-Georg Jahnke, Annette G. Beck-Sickinger, Andrea A. Robitzki
Article
Biophysics
Reza Khodadadi, Manouchehr Eghbal, Hamideh Ofoghi, Alireza Balaei, Ali Tamayol, Karen Abrinia, Amir Sanati-Nezhad, Mohamadmahdi Samandari
Summary: This paper introduces an integrated portable centrifugal microfluidic system that automates cell and fluid manipulation for complete blood counting (CBC) analysis at the point-of-care (POC). The system utilizes a specially designed microfluidic disc for cell separation, solution metering and mixing, and cell counting, and is equipped with a custom script for automated quantification of cells. The proposed method shows a strong correlation with the gold standard hematology analyzer for various blood parameters. The portable system offers simplicity, affordability, and low power consumption, making it a potential solution for improving healthcare delivery in resource-limited settings and remote areas.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Nabil H. Bhuiyan, Joon S. Shim
Summary: Developing herd immunity is crucial for changing the course of the COVID-19 pandemic. An AI-driven point-of-care testing platform has been proposed for analyzing the body's response to SARS-CoV-2, and it has been successfully used for quantifying viral proteins and antibodies in blood samples. A data-receptive web-based dashboard system has also been developed for real-time analysis of herd immunity progress.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Alexiane Godain, Timothy M. Vogel, Pascal Fongarland, Naoufel Haddour
Summary: This study provides comprehensive insights into the intricate relationship between shear stress and electroactive biofilms in microbial fuel cells, highlighting the pivotal role of shear stress in influencing the growth kinetics, electrical performance, and physical structure of the biofilms. The study also emphasizes the complexities of extracellular electron transfer mechanisms and the need for complementary metaproteomic analyses.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Linjie Wang, Yixin Chen, Yang Ji, Shujun Zheng, Fei Wang, Caolong Li
Summary: A paper-based biosensor incorporating surface-enhanced Raman spectroscopy (SERS) and colorimetric detection has been developed for efficient quantification of intracellular glutathione (GSH). The biosensor exhibits excellent selectivity, stability, and precision, with low detection limits in both SERS and colorimetric modes. It has been successfully utilized for intracellular GSH detection and validated against a commercial GSH assay kit.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Quan Zhou, Jing Wang, Zhen Zhang, Alain Wuethrich, Richard J. Lobb, Matt Trau
Summary: This study presents a biosensor for sensitive detection of EMT-associated biomarkers on extracellular vesicles (EVs) surfaces during targeted therapy. Through longitudinal monitoring of patients, the biosensor shows its ability to identify the EMT-like phenotype switching on circulating EVs during the development of resistance.
BIOSENSORS & BIOELECTRONICS
(2024)
Review
Biophysics
Pratika Rai, Sabrina N. Hoba, Celine Buchmann, Robert J. Subirana-Slotos, Christian Kersten, Tanja Schirmeister, Kristina Endres, Bernd Bufe, Alexey Tarasov
Summary: Proteases have been proposed as potential biomarkers for various pathological conditions. The development of protease biosensors offers a more efficient way to investigate dysregulated proteases. This review article presents different optical and electrochemical detection methods for designing biosensors for all major protease families.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Chengxin Liu, Xu Shen, Li Yan, Runlian Qu, Yue Wang, Yaqin He, Zixuan Zhan, Piaopiao Chen, Feng Lin
Summary: In this study, a homogeneous rapid electrochemical aptasensor was developed to quantitatively detect CTCs in lung cancer patients. The aptasensor utilized a DNA nanosphere structure and a complementary aptamer to specifically detect mucin 1 as a marker for CTCs. The assay exhibited high specificity and sensitivity, and the results were consistent with other detection methods.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Danni Xue, Xing Dai, Jialong Zhao, Jiayao Zhang, Huan Liu, Kui Liu, Tao Xu, Chenjie Gu, Xingfei Zhou, Tao Jiang
Summary: In this study, a dual-enhancement SERS substrate based on Ti3C2TX and Ag nanocubes was fabricated for precise quantification of ritonavir and ibrutinib in serum. The formation of numerous electromagnetic hotspots between Ag nanocubes facilitated effective photo-induced charge transfer. The composite substrate showed excellent sensitivity, achieving low detection limits and high recoveries, making it promising for monitoring and identification of clinical blood drug concentration.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Tenghua Zhang, Zihui Xie, Xiaohe Zheng, Yuxin Liang, Yao Lu, Hankang Zhong, Feiyang Qian, Yuqing Zhu, Ruiting Sun, Yan Sheng, Jiaming Hu
Summary: This study reports a technology based on cationic lipid-polymer hybrid nanoparticles for efficient extracellular vesicle (EV) enrichment and in-situ detection of internal microRNAs. The technology demonstrates high EV enrichment efficiency and sensitive internal RNA detection, making it potentially useful for early pancreatic cancer diagnosis.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Wenjie Dai, Gaoxu Chen, Xiaoyan Wang, Shujun Zhen, Chengzhi Huang, Lei Zhan, Yuanfang Li
Summary: In this study, a novel metal organic gel (MOG) with dual electrochemiluminescence (ECL) properties was prepared by simple mixing. The MOG exhibited strong and stable anodic and cathodic ECL signals. By utilizing this MOG, an ECL resonance energy transfer (ECL-RET) biosensor was constructed for ultrasensitive detection of a specific gene. The study developed a straightforward technique for obtaining a single luminescent material with dual signals and expanded the analytical application of MOGs in the realm of ECL.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Lais Canniatti Brazaca, Amanda Hikari Imamura, Rodrigo Vieira Blasques, Jessica Rocha Camargo, Bruno Campos Janegitz, Emanuel Carrilho
Summary: The use of microfluidic paper-based analytical devices (muPADs) for medical diagnosis is a growing trend due to their low cost, easy use, simple manufacturing, and potential for application in low-resource settings. This review focuses on the advances in muPADs for medical diagnostics, discussing their use in detecting various biomarkers in common human biofluids. The challenges of biomarker detection in each sample are examined, along with innovative techniques to overcome these limitations. The commercialization difficulties of muPADs are also considered, along with future trends such as wearable devices and integrated platforms.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Minghong Jian, Xudong Sun, Hua Zhang, Xiaotong Li, Shasha Li, Zhenxin Wang
Summary: Matrix metalloproteinases (MMPs) are attractive biomarkers for cancer diagnosis and treatment, but their low abundance in biological samples, especially in the early stages of tumors, makes it challenging to precisely analyze MMP activities. In this study, a peptide microarray-based metal-enhanced fluorescence assay (PMMEFA) is proposed as a sensitive and specific method to simultaneously detect MMP-1, -2, -3, -7, -9, and -13 activities. The PMMEFA showed excellent sensitivity and was capable of detecting MMP activities in various matrices.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Kyung Ho Kim, Eunsu Ryu, Zinah Hilal Khaleel, Sung Eun Seo, Lina Kim, Yong Ho Kim, Hyun Gyu Park, Oh Seok Kwon
Summary: We have developed a novel strategy for discriminative detection of SARS-CoV-2 variants using the plasmonic photothermal effect of gold nanofilms and digital polymerase chain reaction (dPCR) technology. With this method, we were able to detect the delta and omicron variants with high sensitivity within 25 minutes from COVID-19 patients' clinical samples, making it a rapid and accurate point-of-care testing tool.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Zepeng Kang, Yuanming Wang, Haiyan Song, Xueli Wang, Job Zhang, Zhiguang Zhu
Summary: By designing a wearable and flexible lactic-acid/O2 EBFC with an air-breathing biocathode, the limitations of biocathode are effectively solved. The optimal performance conditions are determined through experiments, and the EBFC is successfully applied to power a low-power device.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Huayun Chen, Zhiheng You, Yuhui Hong, Xiao Wang, Mingming Zhao, Yushi Luan, Yibin Ying, Yixian Wang
Summary: This study developed a colorimetric sensor array using gas-responsive two-dimensional metal-organic framework (MOF) composites for highly sensitive detection of volatile organic compounds (VOCs). The dye/Zn-2(bim)(4) composites-based sensor arrays showed enhanced sensitivity and anti-interference properties. The findings demonstrate the potential use of dye/Zn-2(bim)(4) sensor arrays for early perception of plant diseases.
BIOSENSORS & BIOELECTRONICS
(2024)
