Adaptor protein complexes and intracellular transport

AP1S3 Mutations Are Associated with Pustular Psoriasis and Impaired Toll-like Receptor 3 Trafficking

(2014) Niovi Setta-Kaffetzi et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Adaptor proteins involved in polarized sorting

(2014) Juan S. Bonifacino   JOURNAL OF CELL BIOLOGY

The Nef-Like Effect of Murine Leukemia Virus Glycosylated Gag on HIV-1 Infectivity Is Mediated by Its Cytoplasmic Domain and Depends on the AP-2 Adaptor Complex

(2014) Y. Usami et al.   JOURNAL OF VIROLOGY

How HIV-1 Nef hijacks the AP-2 clathrin adaptor to downregulate CD4

(2014) Xuefeng Ren et al.   eLife

Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression

(2013) Lei S. Qi et al.   CELL

Structural Basis for Recruitment and Activation of the AP-1 Clathrin Adaptor Complex by Arf1

(2013) Xuefeng Ren et al.   CELL

Self-Assembly of VPS41 Promotes Sorting Required for Biogenesis of the Regulated Secretory Pathway

(2013) Cédric S. Asensio et al.   DEVELOPMENTAL CELL

The Adaptor Protein-1 μ1B Subunit Expands the Repertoire of Basolateral Sorting Signal Recognition in Epithelial Cells

(2013) Xiaoli Guo et al.   DEVELOPMENTAL CELL

AP1S2 is mutated in X-linked Dandy–Walker malformation with intellectual disability, basal ganglia disease and seizures (Pettigrew syndrome)

(2013) Pierre Cacciagli et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

AP-1B−Mediated Protein Sorting Regulates Polarity and Proliferation of Intestinal Epithelial Cells in Mice

(2013) Koji Hase et al.   GASTROENTEROLOGY

Structural Basis for the Recognition of Tyrosine-based Sorting Signals by the μ3A Subunit of the AP-3 Adaptor Complex

(2013) Gonzalo A. Mardones et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Trafficking of the Menkes copper transporter ATP7A is regulated by clathrin-, AP-2–, AP-1–, and Rab22-dependent steps

(2013) Zoe G. Holloway et al.   MOLECULAR BIOLOGY OF THE CELL

Interaction between AP-5 and the hereditary spastic paraplegia proteins SPG11 and SPG15

(2013) Jennifer Hirst et al.   MOLECULAR BIOLOGY OF THE CELL

A Structure-Based Mechanism for Arf1-Dependent Recruitment of Coatomer to Membranes

(2012) Xinchao Yu et al.   CELL

The Clathrin Adaptor AP-1A Mediates Basolateral Polarity

(2012) Diego Gravotta et al.   DEVELOPMENTAL CELL

Entry of Hepatitis B Virus into Immortalized Human Primary Hepatocytes by Clathrin-Dependent Endocytosis

(2012) H.-C. Huang et al.   JOURNAL OF VIROLOGY

Mutations in AP2S1 cause familial hypocalciuric hypercalcemia type 3

(2012) M Andrew Nesbit et al.   NATURE GENETICS

Structural basis of evasion of cellular adaptive immunity by HIV-1 Nef

(2012) Xiaofei Jia et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mutation in the AP4B1 gene cause hereditary spastic paraplegia type 47 (SPG47)

(2012) Peter Bauer et al.   NEUROGENETICS

Signal-Mediated, AP-1/Clathrin-Dependent Sorting of Transmembrane Receptors to the Somatodendritic Domain of Hippocampal Neurons

(2012) Ginny G. Farías et al.   NEURON

Adaptor Protein Complexes AP-4 and AP-5: New Players in Endosomal Trafficking and Progressive Spastic Paraplegia

(2012) Jennifer Hirst et al.   TRAFFIC

Identification and Targeting of an Interaction between a Tyrosine Motif within Hepatitis C Virus Core Protein and AP2M1 Essential for Viral Assembly

(2012) Gregory Neveu et al.   PLoS Pathogens

Adaptor Protein Complex 4 Deficiency Causes Severe Autosomal-Recessive Intellectual Disability, Progressive Spastic Paraplegia, Shy Character, and Short Stature

(2011) Rami Abou Jamra et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The Epithelia-Specific Membrane Trafficking Factor AP-1B Controls Gut Immune Homeostasis in Mice

(2011) Daisuke Takahashi et al.   GASTROENTEROLOGY

AP1B plays an important role in intestinal tumorigenesis with the truncating mutation of an APC gene

(2011) Mitsuko Mimura et al.   INTERNATIONAL JOURNAL OF CANCER

Arf6 regulates AP-1B–dependent sorting in polarized epithelial cells

(2011) Elina Shteyn et al.   JOURNAL OF CELL BIOLOGY

AP-1 and clathrin are essential for secretory granule biogenesis in Drosophila

(2011) Jason Burgess et al.   MOLECULAR BIOLOGY OF THE CELL

Deep sequencing reveals 50 novel genes for recessive cognitive disorders

(2011) Hossein Najmabadi et al.   NATURE

The Fifth Adaptor Protein Complex

(2011) Jennifer Hirst et al.   PLOS BIOLOGY

A Large-Scale Conformational Change Couples Membrane Recruitment to Cargo Binding in the AP2 Clathrin Adaptor Complex

(2010) Lauren P. Jackson et al.   CELL

Sorting of the Alzheimer's Disease Amyloid Precursor Protein Mediated by the AP-4 Complex

(2010) Patricia V. Burgos et al.   DEVELOPMENTAL CELL

AP-1/σ1B-adaptin mediates endosomal synaptic vesicle recycling, learning and memory

(2010) Nataliya Glyvuk et al.   EMBO JOURNAL

Conservation and Diversification of Dileucine Signal Recognition by Adaptor Protein (AP) Complex Variants

(2010) Rafael Mattera et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of a membrane curvature–sensing motif switches function of the HOPS subunit Vps41 in membrane tethering

(2010) Margarita Cabrera et al.   JOURNAL OF CELL BIOLOGY

Adaptor protein complex-4 (AP-4) deficiency causes a novel autosomal recessive cerebral palsy syndrome with microcephaly and intellectual disability

(2010) A. Moreno-De-Luca et al.   JOURNAL OF MEDICAL GENETICS

A Genome-Scale DNA Repair RNAi Screen Identifies SPG48 as a Novel Gene Associated with Hereditary Spastic Paraplegia

(2010) Mikołaj Słabicki et al.   PLOS BIOLOGY

Mutation in the AP4M1 Gene Provides a Model for Neuroaxonal Injury in Cerebral Palsy

(2009) Annemieke J.M.H. Verkerk et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Endocytic trafficking of activated EGFR is AP-2 dependent and occurs through preformed clathrin spots

(2009) J. Z. Rappoport et al.   JOURNAL OF CELL SCIENCE

Phosphatidylinositol 3,4,5-trisphosphate Localization in Recycling Endosomes Is Necessary for AP-1B–dependent Sorting in Polarized Epithelial Cells

(2009) Ian C. Fields et al.   MOLECULAR BIOLOGY OF THE CELL

Tickets to ride: selecting cargo for clathrin-regulated internalization

(2009) Linton M. Traub   NATURE REVIEWS MOLECULAR CELL BIOLOGY

AP-2-dependent Internalization of Potassium Channel Kir2.3 Is Driven by a Novel Di-hydrophobic Signal

(2008) Amanda K. Mason et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A structural explanation for the binding of endocytic dileucine motifs by the AP2 complex

(2008) Bernard T. Kelly et al.   NATURE

Accumulation of AMPA Receptors in Autophagosomes in Neuronal Axons Lacking Adaptor Protein AP-4

(2008) Shinji Matsuda et al.   NEURON

Disruption of AP1S1, Causing a Novel Neurocutaneous Syndrome, Perturbs Development of the Skin and Spinal Cord

(2008) Alexandre Montpetit et al.   PLoS Genetics