Novel human ᴅ-amino acid oxidase inhibitors stabilize an active-site lid-open conformation

Synthesis of kojic acid derivatives as secondary binding site probes of d-amino acid oxidase

(2013) Mithun Raje et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

D-Amino Acid Oxidase Inhibitors as a Novel Class of Drugs for Schizophrenia Therapy

(2013) Silvia Sacchi et al.   CURRENT PHARMACEUTICAL DESIGN

4-Hydroxypyridazin-3(2H)-one Derivatives as Novel d-Amino Acid Oxidase Inhibitors

(2013) Takeshi Hondo et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structural, Kinetic, and Pharmacodynamic Mechanisms of d-Amino Acid Oxidase Inhibition by Small Molecules

(2013) Seth C. Hopkins et al.   JOURNAL OF MEDICINAL CHEMISTRY

NMDA receptors in nervous system diseases

(2013) Qiang Zhou et al.   NEUROPHARMACOLOGY

Multiple risk pathways for schizophrenia converge in serine racemase knockout mice, a mouse model of NMDA receptor hypofunction

(2013) D. T. Balu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure–function relationships in human d-amino acid oxidase

(2012) Silvia Sacchi et al.   AMINO ACIDS

Synaptic and Extrasynaptic NMDA Receptors Are Gated by Different Endogenous Coagonists

(2012) Thomas Papouin et al.   CELL

Demystifying Brain Penetration in Central Nervous System Drug Discovery

(2012) Li Di et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and SAR of 1-Hydroxy-1H-benzo[d]imidazol-2(3H)-ones as Inhibitors of d-Amino Acid Oxidase

(2012) James F. Berry et al.   ACS Medicinal Chemistry Letters

Impact of enzyme concentration and residence time on apparent activity recovery in jump dilution analysis

(2011) Robert A. Copeland et al.   ANALYTICAL BIOCHEMISTRY

Serine racemase and the serine shuttle between neurons and astrocytes

(2011) Herman Wolosker   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

d -Amino acid oxidase-mediated increase in spinal hydrogen peroxide is mainly responsible for formalin-induced tonic pain

(2011) Jin-Miao Lu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Is rat an appropriate animal model to study the involvement of d-serine catabolism in schizophrenia? insights from characterization of d-amino acid oxidase

(2011) Luca F. Frattini et al.   FEBS Journal

FRED Pose Prediction and Virtual Screening Accuracy

(2011) Mark McGann   Journal of Chemical Information and Modeling

A Unified, Probabilistic Framework for Structure- and Ligand-Based Virtual Screening

(2011) Steven L. Swann et al.   JOURNAL OF MEDICINAL CHEMISTRY

Modulation of NMDA receptor function by inhibition of d-amino acid oxidase in rodent brain

(2011) Christine A. Strick et al.   NEUROPHARMACOLOGY

N-methyl-d-aspartate (NMDA) receptor dysfunction or dysregulation: The final common pathway on the road to schizophrenia?

(2010) Joshua T. Kantrowitz et al.   BRAIN RESEARCH BULLETIN

Metabolism of the neuromodulator d-serine

(2010) Loredano Pollegioni et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Extended-Connectivity Fingerprints

(2010) David Rogers et al.   Journal of Chemical Information and Modeling

Long-term potentiation depends on release of d-serine from astrocytes

(2010) Christian Henneberger et al.   NATURE

Discovery, SAR, and Pharmacokinetics of a Novel 3-Hydroxyquinolin-2(1H)-one Series of Potentd-Amino Acid Oxidase (DAAO) Inhibitors†

(2009) Allen J. Duplantier et al.   JOURNAL OF MEDICINAL CHEMISTRY

Spinal D-Amino Acid Oxidase Contributes to Neuropathic Pain in Rats

(2009) W.-J. Zhao et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The neurobiology of D-amino acid oxidase and its involvement in schizophrenia

(2009) L Verrall et al.   MOLECULAR PSYCHIATRY

The discovery of fused pyrrole carboxylic acids as novel, potent d-amino acid oxidase (DAO) inhibitors

(2008) Tim Sparey et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

pLG72 Modulates Intracellular D-Serine Levels through Its Interaction with D-Amino Acid Oxidase

(2008) Silvia Sacchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Application of Belief Theory to Similarity Data Fusion for Use in Analog Searching and Lead Hopping

(2008) Steven W. Muchmore et al.   Journal of Chemical Information and Modeling

Synthesis and Biological Evaluation ofd-Amino Acid Oxidase Inhibitors

(2008) Dana Ferraris et al.   JOURNAL OF MEDICINAL CHEMISTRY

Targeted disruption of serine racemase affects glutamatergic neurotransmission and behavior

(2008) A C Basu et al.   MOLECULAR PSYCHIATRY

Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia

(2008) John E. Lisman et al.   TRENDS IN NEUROSCIENCES

Catalytic Properties of d-Amino Acid Oxidase in Cephalosporin C Bioconversion: A Comparison between Proteins from Different Sources

(2004) Loredano Pollegioni et al.   BIOTECHNOLOGY PROGRESS