Article
Biochemistry & Molecular Biology
Kenji Watanabe, Shuichi Shibuya, Yusuke Ozawa, Toshihiko Toda, Takahiko Shimizu
Summary: The study showed that p53 regulated ROS-mediated apoptotic cell death and tumorigenesis, but did not affect ROS-mediated tissue degeneration in SOD-deficient models.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biology
ShylajaNaciyar Mohandass, Mangalalakshmi Ragavan, Dineshbabu Gnanasekaran, Uma Lakshmanan, Prabaharan Dharmar, Sushanta Kumar Saha
Summary: Synthetic azo dyes are widely used but their improper discharge poses a threat to the environment. Genetically modified cyanobacteria with enhanced H2O2 accumulation through SOD overexpression can effectively degrade these dyes, suggesting a valuable bioremediation strategy.
Article
Biochemistry & Molecular Biology
Edurne Tellechea, Aaron C. Asensio, Paula Ciaurriz, Javier Buezo, Pedro Lopez-Gomez, Marina Urra, Jose F. Moran
Summary: This study investigates the characteristics of the recombinant cowpea FeSOD immobilized onto gold nanoparticles (AuNPs) and the effects of NP surface chemistry and biofunctionalization methods on enzyme activity. The results highlight the importance of the biomolecule and AuNP interaction for the functionality of the hybrid and demonstrate the potential of these strategies in biomedical applications.
Editorial Material
Biochemistry & Molecular Biology
Hosni M. Hassan
Summary: This commentary discusses the origin of the concept of using redox cycling compounds to generate partially reduced oxygen species to cause oxidative stress. It describes how this finding revolutionized the field of oxygen free radicals and oxidative stress and its continued relevance and impact in the field.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
(2022)
Article
Multidisciplinary Sciences
Jay L. Zweier, Craig Hemann, Tapan Kundu, Mohamed G. Ewees, Sahar A. Khaleel, Alexandre Samouilov, Govindasamy Ilangovan, Mohamed A. El-Mahdy
Summary: Cytoglobin (Cygb) has potent superoxide dismutase (SOD) function, rapidly dismutating superoxide in cells to protect against oxidative stress. Its role in cellular superoxide metabolism is important due to its ubiquitous expression in cells at micromolar concentrations.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Review
Biochemistry & Molecular Biology
Brianne R. O'Leary, Rory S. Carroll, Garett J. Steers, Jennifer Hrabe, Frederick E. Domann, Joseph J. Cullen
Summary: Reactive oxygen species are essential components in cell signaling and immune responses, but an imbalance can lead to oxidative stress. Cancer cells show increased oxidative stress and decreased expression of extracellular superoxide dismutase, an antioxidant enzyme that plays a role in maintaining redox balance and protecting against oxidative damage. Understanding the role of EcSOD in cancer could have potential implications for detection, prognosis, and treatment of malignancies.
Article
Plant Sciences
Jovana Sucur Elez, Kristina Petrovic, Marina Crnkovic, Slobodan Krsmanovic, Milos Rajkovic, Zeljko Kaitovic, Dorde Malencic
Summary: The study evaluated oxidative stress and lesion length in soybean seedlings infected with the fungus Macrophomina phaseolina to determine the most tolerant soybean cultivar. Superoxide anion radical production and superoxide-dismutase (SOD) activity were highest in the Favorit cultivar, indicating its tolerance to M. phaseolina. In contrast, the Victoria cultivar showed high radical production, low SOD activity, and enhanced lipid peroxidation, suggesting its susceptibility to the pathogen. No significant differences were observed in the oxidative stress parameters of the Atlas and Rubin cultivars compared to the control. The Victoria cultivar had the longest lesion length, while the Atlas and Rubin cultivars displayed the shortest lengths, indicating their tolerance to the pathogen.
Article
Biochemistry & Molecular Biology
Monireh Fesharaki-Esfahani, Azar Shahpiri, Akram Kazemi-Nasab
Summary: Avicennia marina is a mangrove species with high tolerance to salt, hydrogen peroxide, and heavy metals. The enzyme superoxide dismutase (SOD) activity in response to hydrogen peroxide was increased. The gene encoding AmSOD1 was isolated and cloned, and its heterologous expression in E. coli showed increased tolerance to hydrogen peroxide treatment.
Article
Chemistry, Physical
Shan Chen, Congcong Yin, Zongxiong Huang, Junyan Chen, Yuhao Zheng, Jinghu Chen, Shuangli Yang, Yuwen Su, Yimin Fang
Summary: Graphene exhibits the ability to undergo oxygen evolution reaction and form oxygen nanobubbles at negative potential, acting as a mimic of superoxide dismutase (SOD). Catalytic sites are distributed at the edge and bulk of graphene, rather than on metal oxide residues. Metal oxide nanoparticles on the graphene sheet play an important role in promoting the catalysis by increasing the concentration of superoxide through an electrocatalyzed Fenton reaction.
Article
Chemistry, Multidisciplinary
Joo-Eun Kim, Hyun-Wook Lee, Won-Jin Kwak
Summary: In this study, 4-carboxy-TEMPO was selected as a representative SODm, and its ability to effectively promote the disproportionation reaction and accelerate the generation of singlet oxygen was chemically verified. It was found that the release of singlet oxygen evolved by the SODm was decreased when using a quencher. This study provides important reference for the development of additives for practical application of LOBs.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Review
Chemistry, Analytical
Wanchao Yu, Lixia Zhao
Summary: ROS, as important oxidizing species in ecosystems, play various roles and monitoring their concentration is crucial for the environment. The chemiluminescence method has attracted attention for ROS detection due to its high sensitivity and simplicity, showing advances in recent years.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2021)
Article
Plant Sciences
Giovanna Salbitani, Angela Perrone, Luigi Rosati, Carmen Laezza, Simona Carfagna
Summary: This study investigates the effects of sulfur deprivation on Galdieria sulphuraria and reveals that it leads to a decrease in total protein content and an increase in soluble protein fraction. The glutathione content in Galdieria sulphuraria remains high even under sulfur deprivation.
Article
Biochemistry & Molecular Biology
Eun-Nam Kim, Ga-Ram Kim, Jae Sik Yu, Ki Hyun Kim, Gil-Saeng Jeong
Summary: The study found that BAG can inhibit osteoclast differentiation and ROS production, restore the expression of antioxidant enzymes, suppress the phosphorylation of MAPKs and translocation of NF-kappa beta, and restore the mineralization of lost osteoblasts, suggesting its potential as a new natural product-derived treatment for bone diseases.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Fisheries
Min Yang, Luchuanyang Sun, Yasunosuke Kawabata, Takahiro Maegawa, Shigeto Taniyama, Katsuyasu Tachibana, Katsuya Hirasaka
Summary: Balenine, an endogenous imidazole dipeptide composed of beta-alanine and 3-methyl-l-histidine, is found mainly in muscles and the brain. Studies have shown that balenine exhibits antioxidant activity by increasing SOD activity without affecting other antioxidant enzymes. This suggests that balenine contributes to antioxidant effects through activation of SOD.
Article
Forestry
Ya Chen, Hua Wu, Zhaodong Hao, Liming Zhu, Lu Lu, Jisen Shi, Jinhui Chen
Summary: This study systematically identified and analyzed the SOD gene family of woody plant Liriodendron chinense, and investigated the transcriptional responses of LcSOD genes to abiotic stresses. A total of eight SOD genes were identified and divided into two subgroups. The gene expression analysis revealed the response of LcSOD genes to abiotic stresses, providing potential targets for improving stress tolerance in L. chinense.
Article
Geriatrics & Gerontology
Gabrielle A. Lockett, Edward J. Almond, Timothy J. Huggins, Joel D. Parker, Andrew F. G. Bourke
EXPERIMENTAL GERONTOLOGY
(2016)
Article
Physiology
Andrew D. Nguyen, Kerri DeNovellis, Skyler Resendez, Jeremy D. Pustilnik, Nicholas J. Gotelli, Joel D. Parker, Sara Helms Cahan
JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMS AND ENVIRONMENTAL PHYSIOLOGY
(2017)
Article
Biodiversity Conservation
Stephanie Bird, Joel Parker
JOURNAL OF INSECT CONSERVATION
(2014)
Article
Ecology
Edward J. Almond, Timothy J. Huggins, Liam P. Crowther, Joel D. Parker, Andrew F. G. Bourke
AMERICAN NATURALIST
(2019)
Article
Entomology
Joel D. Parker
MYRMECOLOGICAL NEWS
(2010)
Article
Cell Biology
Stephanie Jemielity, Masayuki Kimura, Karen M. Parker, Joel D. Parker, Xiaojian Cao, Abraham Aviv, Laurent Keller
Article
Biochemistry & Molecular Biology
Johannes Graeff, Stephanie Jemielity, Joel D. Parker, Karen M. Parker, Laurent Keller
Article
Biochemistry & Molecular Biology
SH Cahan, GE Julian, SW Rissing, T Schwander, JD Parker, L Keller
Article
Biochemistry & Molecular Biology
JD Parker, KM Parker, L Keller
INSECT MOLECULAR BIOLOGY
(2004)
Article
Multidisciplinary Sciences
JD Parker, KM Parker, BH Sohal, RS Sohal, L Keller
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2004)
Article
Biochemistry & Molecular Biology
JD Parker, RE Ziemba, SH Cahan, SW Rissing
BIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATION
(2004)
Article
Ecology
JD Parker, SW Rissing
Review
Geriatrics & Gerontology
Stephanie Jemielity, Michel Chapuisat, Joel D. Parker, Laurent Keller
Article
Genetics & Heredity
MP Miller, JD Parker, SW Rissing, S Kumar
ANNALS OF HUMAN GENETICS
(2003)