Molecular determinants involved in activation of caspase 7

FLIPLinduces caspase 8 activity in the absence of interdomain caspase 8 cleavage and alters substrate specificity

(2011) Cristina Pop et al.   BIOCHEMICAL JOURNAL

From discovering to understanding

(2010) Ralf Dahm   EMBO REPORTS

Inducible Dimerization and Inducible Cleavage Reveal a Requirement for Both Processes in Caspase-8 Activation

(2010) Andrew Oberst et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A constitutively active and uninhibitable caspase-3 zymogen efficiently induces apoptosis

(2009) Jad Walters et al.   BIOCHEMICAL JOURNAL

The Jekyll and Hyde Functions of Caspases

(2009) Caroline H. Yi et al.   DEVELOPMENTAL CELL

The Apaf-1•procaspase-9 apoptosome complex functions as a proteolytic-based molecular timer

(2009) Srinivas Malladi et al.   EMBO JOURNAL

The E3 Ubiquitin Ligase cIAP1 Binds and Ubiquitinates Caspase-3 and -7 via Unique Mechanisms at Distinct Steps in Their Processing

(2009) Young Eun Choi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural and kinetic determinants of protease substrates

(2009) John C Timmer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

L2′ loop is critical for caspase-7 active site formation

(2009) Witold A. Witkowski et al.   PROTEIN SCIENCE

Structural and Biochemical Studies on Procaspase-8: New Insights on Initiator Caspase Activation

(2009) Nadine Keller et al.   STRUCTURE

Structural basis for executioner caspase recognition of P5 position in substrates

(2008) Guoxing Fu et al.   APOPTOSIS

Executioner caspase-3 and caspase-7 are functionally distinct proteases

(2008) J. G. Walsh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA