Journal
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
Volume 73, Issue 6, Pages 1422-1424Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1271/bbb.80843
Keywords
Bifidobacterium adolescentis; tiling array; genomic polymorphism; self-organizing map (SOM); DNA microarray
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Funding
- Ministry of Education, Culture, Sports, Science, and Technology of Japan
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Six Bifidobacterium adolescentis strains, JCM1275, JCM1251, JCM7044, JCM7045, JCM7046, and 9-124, were analyzed using a tiling array designed according to the full genome sequence of ATCC15703. The results demonstrated deletion clusters along with single-gene mutations and deletions. Most deletions concerned genes involved in polysaccharide and cell-surface biogenesis. A dendrogram illustrating the deletions and mutations is presented and the evolution of B. adolescentis is discussed.
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