Discovery of 2-chloro-N-((4,4-difluoro-1-hydroxycyclohexyl)methyl)-5-(5-fluoropyrimidin-2-yl)benzamide as a potent and CNS penetrable P2X7 receptor antagonist

Title
Discovery of 2-chloro-N-((4,4-difluoro-1-hydroxycyclohexyl)methyl)-5-(5-fluoropyrimidin-2-yl)benzamide as a potent and CNS penetrable P2X7 receptor antagonist
Authors
Keywords
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Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 20, Issue 10, Pages 3107-3111
Publisher
Elsevier BV
Online
2010-03-31
DOI
10.1016/j.bmcl.2010.03.094

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