Optimizing the lipidomics workflow for clinical studies—practical considerations
Published 2015 View Full Article
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Title
Optimizing the lipidomics workflow for clinical studies—practical considerations
Authors
Keywords
Biomarkers, Lipidomics, Mass spectrometry, Metabolomics, Systems biology, Systems medicine
Journal
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
Volume 407, Issue 17, Pages 4973-4993
Publisher
Springer Nature
Online
2015-04-08
DOI
10.1007/s00216-015-8633-2
References
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Note: Only part of the references are listed.- The influence of sample collection methodology and sample preprocessing on the blood metabolic profile
- (2015) Benedicte Jørgenrud et al. Bioanalysis
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- (2014) Cyrus Papan et al. ANALYTICAL CHEMISTRY
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- (2014) Tuulia P. I. Lintonen et al. ANALYTICAL CHEMISTRY
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- (2014) Miao Wang et al. ANALYTICAL CHEMISTRY
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- (2014) Giuseppe Paglia et al. ANALYTICAL CHEMISTRY
- Lipidomics Profiling and Risk of Cardiovascular Disease in the Prospective Population-Based Bruneck Study
- (2014) Christin Stegemann et al. CIRCULATION
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- (2014) Eva Gorrochategui et al. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
- Comparative evaluation of preprocessing freeware on chromatography/mass spectrometry data for signature discovery
- (2014) Jamie B. Coble et al. JOURNAL OF CHROMATOGRAPHY A
- Optimizing a ultrahigh pressure liquid chromatography-time of flight-mass spectrometry approach using a novel sub-2μm core–shell particle for in depth lipidomic profiling of Caenorhabditis elegans
- (2014) Michael Witting et al. JOURNAL OF CHROMATOGRAPHY A
- Diurnal Regulation of Lipid Metabolism and Applications of Circadian Lipidomics
- (2014) Joshua J. Gooley et al. Journal of Genetics and Genomics
- Challenges in accurate quantitation of lysophosphatidic acids in human biofluids
- (2014) Joelle M. Onorato et al. JOURNAL OF LIPID RESEARCH
- Isoenergetic diets differing in theirn-3 fatty acid and polyphenol content reflect different plasma and HDL-fraction lipidomic profiles in subjects at high cardiovascular risk
- (2014) Isabel Bondia-Pons et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Plasma and Serum Lipidomics of Healthy White Adults Shows Characteristic Profiles by Subjects’ Gender and Age
- (2014) Masaki Ishikawa et al. PLoS One
- Mealtime, Temporal, and Daily Variability of the Human Urinary and Plasma Metabolomes in a Tightly Controlled Environment
- (2014) Kyoungmi Kim et al. PLoS One
- Targeted Metabolomics Identifies Reliable and Stable Metabolites in Human Serum and Plasma Samples
- (2014) Michaela Breier et al. PLoS One
- Systems biology strategies to study lipidomes in health and disease
- (2014) Tuulia Hyötyläinen et al. PROGRESS IN LIPID RESEARCH
- Accurate mass searching of individual lipid species candidates from high-resolution mass spectra for shotgun lipidomics
- (2014) Miao Wang et al. RAPID COMMUNICATIONS IN MASS SPECTROMETRY
- Detection of batch effects in liquid chromatography-mass spectrometry metabolomic data using guided principal component analysis
- (2014) J. Kuligowski et al. TALANTA
- Comprehensive analysis of lipids in biological systems by liquid chromatography-mass spectrometry
- (2014) Tomas Cajka et al. TRAC-TRENDS IN ANALYTICAL CHEMISTRY
- Long-Term Performance and Stability of Molecular Shotgun Lipidomic Analysis of Human Plasma Samples
- (2013) Laura A. Heiskanen et al. ANALYTICAL CHEMISTRY
- Liquid Chromatography–Tandem Mass Spectrometry-Based Plasma Metabonomics Delineate the Effect of Metabolites’ Stability on Reliability of Potential Biomarkers
- (2013) Wei Yang et al. ANALYTICAL CHEMISTRY
- Fatty Acidomics: Global Analysis of Lipid Species Containing a Carboxyl Group with a Charge-Remote Fragmentation-Assisted Approach
- (2013) Miao Wang et al. ANALYTICAL CHEMISTRY
- Lipidomics from an analytical perspective
- (2013) Koen Sandra et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Plasma lipid profiling in a large population-based cohort
- (2013) Jacquelyn M. Weir et al. JOURNAL OF LIPID RESEARCH
- LipidBlast in silico tandem mass spectrometry database for lipid identification
- (2013) Tobias Kind et al. NATURE METHODS
- LipidHome: A Database of Theoretical Lipids Optimized for High Throughput Mass Spectrometry Lipidomics
- (2013) Joseph M. Foster et al. PLoS One
- Analysis of Lipid Experiments (ALEX): A Software Framework for Analysis of High-Resolution Shotgun Lipidomics Data
- (2013) Peter Husen et al. PLoS One
- Extensive diversity in circadian regulation of plasma lipids and evidence for different circadian metabolic phenotypes in humans
- (2013) E. C.-P. Chua et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Surface analysis of lipids by mass spectrometry: More than just imaging
- (2013) Shane R. Ellis et al. PROGRESS IN LIPID RESEARCH
- Enhanced data-independent analysis of lipids using ion mobility-TOFMSEto unravel quantitative and qualitative information in human plasma
- (2013) Vinit Shah et al. RAPID COMMUNICATIONS IN MASS SPECTROMETRY
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- (2013) Huong T. Pham et al. RAPID COMMUNICATIONS IN MASS SPECTROMETRY
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- (2012) Ana I. Perez-Caballero et al. ATHEROSCLEROSIS
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- (2011) Yueyang Zhong et al. ANALYST
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- (2011) Susan S. Bird et al. ANALYTICAL CHEMISTRY
- Applications of Mass Spectrometry to Lipids and Membranes
- (2011) Richard Harkewicz et al. Annual Review of Biochemistry
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- (2011) David S. Myers et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Lipid analysis and lipidomics by structurally selective ion mobility-mass spectrometry
- (2011) Michal Kliman et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
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- (2011) Maria Lankinen et al. PLoS One
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- (2011) Jun Feng Xiao et al. TRAC-TRENDS IN ANALYTICAL CHEMISTRY
- Discovery of Sexual Dimorphisms in Metabolic and Genetic Biomarkers
- (2011) Kirstin Mittelstrass et al. PLoS Genetics
- A novel informatics concept for high-throughput shotgun lipidomics based on the molecular fragmentation query language
- (2011) Ronny Herzog et al. GENOME BIOLOGY
- Lipidomics Profiling by High-Resolution LC−MS and High-Energy Collisional Dissociation Fragmentation: Focus on Characterization of Mitochondrial Cardiolipins and Monolysocardiolipins
- (2010) Susan S. Bird et al. ANALYTICAL CHEMISTRY
- Post-Prandial Lipid Levels for Assessing Target Goal Achievement in Type 2 Diabetic Patients Taking Statin
- (2010) Mikyung Kim et al. JOURNAL OF KOREAN MEDICAL SCIENCE
- Blood sphingolipidomics in healthy humans: impact of sample collection methodology
- (2010) Samar M. Hammad et al. JOURNAL OF LIPID RESEARCH
- Lipidomics reveals a remarkable diversity of lipids in human plasma,
- (2010) Oswald Quehenberger et al. JOURNAL OF LIPID RESEARCH
- Comprehensive LC−MSELipidomic Analysis using a Shotgun Approach and Its Application to Biomarker Detection and Identification in Osteoarthritis Patients
- (2010) Jose M. Castro-Perez et al. JOURNAL OF PROTEOME RESEARCH
- Independent filtering increases detection power for high-throughput experiments
- (2010) R. Bourgon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural Characterization of Unsaturated Phosphatidylcholines Using Traveling Wave Ion Mobility Spectrometry
- (2009) Hugh I. Kim et al. ANALYTICAL CHEMISTRY
- MetAlign: Interface-Driven, Versatile Metabolomics Tool for Hyphenated Full-Scan Mass Spectrometry Data Preprocessing
- (2009) Arjen Lommen ANALYTICAL CHEMISTRY
- Automated Lipid Identification and Quantification by Multidimensional Mass Spectrometry-Based Shotgun Lipidomics
- (2009) Kui Yang et al. ANALYTICAL CHEMISTRY
- Development of a Robust and Repeatable UPLC−MS Method for the Long-Term Metabolomic Study of Human Serum
- (2009) Eva Zelena et al. ANALYTICAL CHEMISTRY
- Filtering for increased power for microarray data analysis
- (2009) Amber J Hackstadt et al. BMC BIOINFORMATICS
- Plasmalogens in Biological Systems: Their Role in Oxidative Processes in Biological Membranes, their Contribution to Pathological Processes and Aging and Plasmalogen Analysis
- (2009) J. Leßig et al. CURRENT MEDICINAL CHEMISTRY
- Serum saturated fatty acids containing triacylglycerols are better markers of insulin resistance than total serum triacylglycerol concentrations
- (2009) A. Kotronen et al. DIABETOLOGIA
- The Anti-Inflammatory and Proresolving Mediator Resolvin E1 Protects Mice from Bacterial Pneumonia and Acute Lung Injury
- (2009) H. Seki et al. JOURNAL OF IMMUNOLOGY
- An extremely simple method for extraction of lysophospholipids and phospholipids from blood samples
- (2009) Zhenwen Zhao et al. JOURNAL OF LIPID RESEARCH
- Improved method for the quantification of lysophospholipids including enol ether species by liquid chromatography-tandem mass spectrometry
- (2009) James G. Bollinger et al. JOURNAL OF LIPID RESEARCH
- Effects of sample handling and storage on quantitative lipid analysis in human serum
- (2009) Angela M. Zivkovic et al. Metabolomics
- Fatty Fish Intake Decreases Lipids Related to Inflammation and Insulin Signaling—A Lipidomics Approach
- (2009) Maria Lankinen et al. PLoS One
- Fasting and Nonfasting Lipid Levels
- (2008) Anne Langsted et al. CIRCULATION
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- (2008) Vitali Matyash et al. JOURNAL OF LIPID RESEARCH
- Assessing individual metabolic responsiveness to a lipid challenge using a targeted metabolomic approach
- (2008) Angela M. Zivkovic et al. Metabolomics
- Gender-dependent progression of systemic metabolic states in early childhood
- (2008) Janne Nikkilä et al. Molecular Systems Biology
- Lipidomics: Practical aspects and applications
- (2007) Claude Wolf et al. PROGRESS IN LIPID RESEARCH
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