STAT-Dependent Upregulation of 12/15-Lipoxygenase Contributes to Neuronal Injury after Stroke

Mammalian lipoxygenases and their biological relevance

(2015) Hartmut Kuhn et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Lipoxygenase: An Emerging Target for Stroke Therapy

(2013) Klaus van Leyen   CNS & Neurological Disorders-Drug Targets

Therapeutic modulators of STAT signalling for human diseases

(2013) Gabriella Miklossy et al.   NATURE REVIEWS DRUG DISCOVERY

Inhibition of 12/15-lipoxygenase as therapeutic strategy to treat stroke

(2012) Kazim Yigitkanli et al.   ANNALS OF NEUROLOGY

Following experimental stroke, the recovering brain is vulnerable to lipoxygenase-dependent semaphorin signaling

(2012) Anton Pekcec et al.   FASEB JOURNAL

Epigenetic and transcriptional control of the 15-lipoxygenase-1 gene in a Hodgkin lymphoma cell line

(2011) Cheng Liu et al.   EXPERIMENTAL CELL RESEARCH

Signal transducer and activator of transcription-6 (STAT6) inhibition suppresses renal cyst growth in polycystic kidney disease

(2011) E. E. Olsan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polycystin-1 regulates STAT activity by a dual mechanism

(2011) J. J. Talbot et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bid-mediated mitochondrial damage is a key mechanism in glutamate-induced oxidative stress and AIF-dependent cell death in immortalized HT-22 hippocampal neurons

(2010) S Tobaben et al.   CELL DEATH AND DIFFERENTIATION

Increased Nuclear Apoptosis-Inducing Factor after Transient Focal Ischemia: A 12/15-Lipoxygenase-dependent Organelle Damage Pathway

(2010) Stefanie Pallast et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Reperfusion and Neurovascular Dysfunction in Stroke: from Basic Mechanisms to Potential Strategies for Neuroprotection

(2010) Joo Eun Jung et al.   MOLECULAR NEUROBIOLOGY

JAK/STAT Signaling Pathway Regulates Nox1 and Nox4-Based NADPH Oxidase in Human Aortic Smooth Muscle Cells

(2009) Adrian Manea et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

12/15-Lipoxygenase targets neuronal mitochondria under oxidative stress

(2009) Stefanie Pallast et al.   JOURNAL OF NEUROCHEMISTRY

Regulation of Mn-Superoxide Dismutase Activity and Neuroprotection by STAT3 in Mice after Cerebral Ischemia

(2009) J. E. Jung et al.   JOURNAL OF NEUROSCIENCE

Protecting Against Cerebrovascular Injury

(2008) Guang Jin et al.   STROKE

Novel lipoxygenase inhibitors as neuroprotective reagents

(2007) Klaus van Leyen et al.   JOURNAL OF NEUROSCIENCE RESEARCH