Article
Food Science & Technology
Luyao Zhao, Xiaoliang Duan, Hongbin Liu, Dong Zhang, Qian Wang, Jianlei Liu, Hui Sun
Summary: Through lipidomics analysis, the distinction between Wuchang Daohuaxiang (DHX) rice and other nine rice varieties was identified and verified using 26 potential biomarkers. The developed discrimination method achieved an accuracy of 97.14%. The results provide supplementary tools for supervision departments and industries.
FOOD RESEARCH INTERNATIONAL
(2022)
Article
Food Science & Technology
Xiangyue Chen, Qunyu Gao, Sentai Liao, Yuxiao Zou, Jiangang Yan, Qian Li
Summary: Applying intermolecular co-pigmentation to mulberry anthocyanins can enhance their stability. Among the selected co-pigments, ferulic acid showed the strongest co-pigmentation reaction under specific conditions. Co-pigments with more free hydroxyl groups facilitated the co-pigmentation, and methyl contributed more to color enhancement. Various analysis methods confirmed the formation of hydrogen bonding, π-π stacking, and hydrophobic interaction between co-pigments and mulberry anthocyanins.
Article
Chemistry, Analytical
Jiajin Huang, Lijun Ding, Wenyue Tian, Hui Zhi, Jing Chen, Liangcai Wu, Likang Wang, Juntao Xie, Jingyan Bai, Hongxia Fan, Suqing Zhao, Kun Zhang, Junxia Zheng
Summary: In this study, the polyphenolic profile of Mesona chinensis Benth (MCB) was determined using UPLC-Q-TOF-MS/MS, identifying a total of 57 compounds including 45 polyphenols. Among them, 23 phytochemicals were identified in MCB for the first time. The antioxidant activities were found to be positively correlated with the polyphenolic levels, with MCB produced in Guangdong Raoping showing the best antioxidant activity and strongest inhibitory effect on alpha-glucosidase.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Applied
Ajay Anand, Anusha Komati, Kumar Katragunta, Hussain Shaik, Narendra Kumar Nagendla, Madhusudana Kuncha, Mohana Krishna Reddy Mudiam, Katragadda Suresh Babu, Ashok Kumar Tiwari
Summary: Boiled rhizome of Nymphaea nouchali shows significant antihyperglycemic and antioxidative stress potentials, making it a promising food material for managing hyperglycemia and oxidative stress.
Article
Biochemistry & Molecular Biology
Xiuyun Li, Chenglun Zhang, Enhui Wu, Liang Han, Xiangliang Deng, Zhongfeng Shi
Summary: This study aimed to investigate the effects and mechanisms of action of Osthole (OST) in breast cancer 4T1 cells. The results showed that OST inhibited cell proliferation, blocked cells from remaining in S-phase, and induced apoptosis. OST mainly affected phospholipid biosynthesis, methyl histidine metabolism, pyrimidine metabolism, and beta-oxidation of very long-chain fatty acid pathways in 4T1 cells, possibly via inhibition of mTOR/SREBP1/FASN signaling.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemical Research Methods
Su Guan, Kun Liu, Zimeng Liu, Liping Zhou, Bingjie Jia, Zichen Wang, Yao Nie, Xuyu Zhang
Summary: This study identified potential metabolic biomarkers to improve the diagnostic accuracy of sepsis, through metabolomic profiling and regression analysis. A model incorporating ten metabolic biomarkers and traditional physiological indicators showed better differentiation for sepsis diagnosis. The study suggests metabolomic profiling could be an effective tool for sepsis diagnosis.
JOURNAL OF PROTEOME RESEARCH
(2022)
Article
Medical Laboratory Technology
Zheng Zhong, Yukai Huang, Qidang Huang, Shaoling Zheng, Zhixiang Huang, Weiming Deng, Tianwang Li
Summary: This study investigated the serum metabolic profiling of gout patients compared to healthy controls using UPLC-Q-TOF/MS, revealing significant differences in metabolites between the two groups. Bilirubin was identified as a potential biomarker for gout, and primary bile acid biosynthesis was suggested as a novel metabolic pathway.
CLINICA CHIMICA ACTA
(2021)
Article
Food Science & Technology
Sulem Yali Granados-Balbuena, Ericka Santacruz-Juarez, Daniel Canseco-Gonzalez, Lucia Aztatzi-Rugerio, Lilia Sanchez-Minutti, Carolina Ramirez-Lopez, Erik Ocaranza-Sanchez
Summary: This study explores the potential of Dahlia pinnata flowers as a source of anthocyanins. The results show that these flowers have a proximate composition similar to other edible flowers and exhibit high antioxidant activity. Additionally, the anthocyanin profile of the flowers contains unique major anthocyanin components, providing opportunities for research in areas such as natural pigment stabilization, food additives, and antioxidants.
JOURNAL OF FOOD SCIENCE
(2022)
Article
Biochemical Research Methods
Hong Huang, Chuanming Fang, Hongxia Niu, Xiangjun Yin, Jiazhao Ruan, Mengying Wei, Yuan Zhou
Summary: Metabolic profiling was used to investigate changes in plasma and urine metabolites following Aβ injection and donepezil treatment in rats. Donepezil improved cognitive impairment induced by Aβ through restoring metabolic disorders. This study provides basic data for understanding the effects of Aβ and donepezil on plasma and urine metabolites in rat models of AD.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
(2023)
Article
Food Science & Technology
Ting Chen, Hanyu Lu, Mingyue Shen, Qiang Yu, Yi Chen, Huiliang Wen, Jianhua Xie
Summary: This study investigated the phytochemical composition, antioxidant activities, and immunomodulatory effects of purple red rice bran pigment extracts (PRBP) on immunosuppressed mice. The results showed that PRBP exhibited excellent antioxidant activities and could alleviate immunosuppression.
FOOD RESEARCH INTERNATIONAL
(2022)
Article
Biochemistry & Molecular Biology
Shengyu Ge, Jinlong Liu, Yang Liu, Jiaqi Song, Hongfeng Wu, Lele Li, Heyun Zhu, Bo Feng
Summary: Ginseng residue, a by-product of ginsenoside extraction, was compared to ginseng tablets using UPLC-Q-TOF/MS analysis, revealing the presence of 39 compounds in both samples. The study found that while ginsenosides were present in small amounts in the residue, a significant amount of polysaccharides was retained. Furthermore, ginseng residue showed strong antioxidant effects, indicating its potential as a functional food raw material.
Article
Biochemistry & Molecular Biology
Yan Wang, Yongqiang Li, Bi Chen, Xianfeng Deng, Qin Luo, Xingru Zao
Summary: Bamboo fruits are rich in phytochemicals such as polyphenols and flavonoids, which have significant antioxidant activities and can protect cells from oxidative damage.
Article
Chemistry, Analytical
Liliang Ju, Jiaxing Zhang, Fujing Wang, Daoqi Zhu, Tingting Pei, Zhuoen He, Zhongxiao Han, Mingqing Wang, Yun Ma, Wei Xiao
Summary: This study identified the major constituents of Houttuynia cordata water extract using UPLC-Q-TOF-MS, including various organic acids, flavonoids, and volatiles. The aqueous extract exhibited cytoprotective activity on muscle cells against oxidative challenge, reversing the decrease in cell viability induced by TNF-a and increasing superoxide dismutase activity.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2021)
Article
Pharmacology & Pharmacy
Qiong Chen, Ting Zhou, Jun-jie Yuan, Xiao-yi Xiong, Xue-hui Liu, Zong-ming Qiu, Lin-lin Hu, Hui Lu, Qian He, Chang Liu, Qing-wu Yang
Summary: This study investigated the metabolic alterations during ischemia-reperfusion injury using metabolomic analysis. A total of 82 differentially expressed metabolites were identified, with some significantly elevated in the reperfusion group. Metabolomics pathway analysis revealed the importance of glycerophospholipid metabolism, linoleic acid metabolism, pyrimidine metabolism, and galactose metabolism in the response to cerebral ischemia-reperfusion. This study provides important insights into the metabolic changes induced by cerebral ischemia-reperfusion.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Lele Li, Zhixia Chang, Keyu Wei, Yi Tang, Zhao Chen, Hongli Zhang, Yang Wang, Heyun Zhu, Bo Feng
Summary: This study proposed a new method for discriminating and quantifying black ginseng. The black ginseng samples were divided into incomplete and complete black ginseng based on accurate quantification of six ginsenosides. Ultrahigh-performance liquid chromatography-quadrupole-time of flight/mass spectrometry (UPLC-Q-TOF/MS) combined with a multivariate statistical analysis strategy was then employed to differentiate the two groups.
