Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 19, Issue 10, Pages 2815-2818Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2009.03.094
Keywords
Bisenediyne bissulphone; Allene; Cycloaromatization; DNA cleavage; Bergman cyclization; Myers-Saito cyclization
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Funding
- CSIR, Government of India
- DST
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A new class of bisenediyne bis sulfones has been synthesized. These molecules underwent cycloaromatization under basic conditions via isomerization to allene and were able to cleave ds-stranded plasmid DNA. (C) 2009 Published by Elsevier Ltd.
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