Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 18, Issue 7, Pages 2440-2444Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2008.02.045
Keywords
chromophore; fluorescence; peptides; peptide nucleic acids; ornithine; 4-aminoproline; solid-phase synthesis; antiproliferative
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The preparation of oligomers made up of several chromophore units as compounds with potential fluorescent and antiproliferative properties is described. Specifically, chromophore units with protected-amino groups and one carboxylic group are described, together with methods to assemble these units using peptide chemistry. Some of these compounds have antiproliferative activity. (C) 2008 Elsevier Ltd. All rights reserved.
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