4.7 Article

Catalyst design in oxidation chemistry; from KMnO4 to artificial metalloenzymes

Journal

BIOORGANIC & MEDICINAL CHEMISTRY
Volume 22, Issue 20, Pages 5657-5677

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmc.2014.07.002

Keywords

Homogenous catalysis; Artificial enzymes; Biocatalysis; Oxidation; N-ligands

Funding

  1. UK Catalysis Hub
  2. EPSRC [EP/K014706/1, EP/K014668/1, EP/K014854/1, EP/K014714/1]
  3. EPSRC for EPSRC Critical mass grant 'Clean catalysis for sustainable development' [EP/J018139/1]
  4. BBSRC - Sasol Technology UK Ltd.
  5. BBSRC [BB/J01446X/1]
  6. BBSRC [BB/J01446X/1] Funding Source: UKRI
  7. EPSRC [EP/K014706/1, EP/K014854/1, EP/K014668/1, EP/K014714/1, EP/J018139/1] Funding Source: UKRI
  8. Biotechnology and Biological Sciences Research Council [1406556, 1358565] Funding Source: researchfish
  9. Engineering and Physical Sciences Research Council [EP/K014854/1, EP/K014706/1, EP/J018139/1, EP/K014668/1, EP/K014714/1] Funding Source: researchfish

Ask authors/readers for more resources

Oxidation reactions are an important part of the synthetic organic chemist's toolkit and continued advancements have, in many cases, resulted in high yields and selectivities. This review aims to give an overview of the current state-of-the-art in oxygenation reactions using both chemical and enzymatic processes, the design principles applied to date and a possible future in the direction of hybrid catalysts combining the best of chemical and natural design. (C) 2014 Elsevier Ltd. All rights reserved.

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