Discovery of the investigational drug TAK-441, a pyrrolo[3,2-c]pyridine derivative, as a highly potent and orally active hedgehog signaling inhibitor: Modification of the core skeleton for improved solubility

Title
Discovery of the investigational drug TAK-441, a pyrrolo[3,2-c]pyridine derivative, as a highly potent and orally active hedgehog signaling inhibitor: Modification of the core skeleton for improved solubility
Authors
Keywords
-
Journal
BIOORGANIC & MEDICINAL CHEMISTRY
Volume 20, Issue 18, Pages 5507-5517
Publisher
Elsevier BV
Online
2012-07-27
DOI
10.1016/j.bmc.2012.07.034

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