Amyloid Precursor Protein (APP) Affects Global Protein Synthesis in Dividing Human Cells

The Pseudophosphatase MK-STYX Physically and Genetically Interacts with the Mitochondrial Phosphatase PTPMT1

(2014) Natalie M. Niemi et al.   PLoS One

Notch1 is required for hypoxia-induced proliferation, invasion and chemoresistance of T-cell acute lymphoblastic leukemia cells

(2013) Jie Zou et al.   Journal of Hematology & Oncology

Amino Acids and mTOR Mediate Distinct Metabolic Checkpoints in Mammalian G1 Cell Cycle

(2013) Mahesh Saqcena et al.   PLoS One

Pseudophosphatase STYX modulates cell-fate decisions and cell migration by spatiotemporal regulation of ERK1/2

(2013) V. Reiterer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Physiological Functions of APP Family Proteins

(2013) U. C. Muller et al.   Cold Spring Harbor Perspectives in Medicine

A ternary complex consisting of AICD, FE65, and TIP60 down-regulates Stathmin1

(2012) Thorsten Müller et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Tissue-Specific Coupling between Insulin/IGF and TORC1 Signaling via PRAS40 in Drosophila

(2012) Cristina Pallares-Cartes et al.   DEVELOPMENTAL CELL

The pseudophosphatase MK-STYX inhibits stress granule assembly independently of Ser149 phosphorylation of G3BP-1

(2012) Justinn E. Barr et al.   FEBS Journal

A unifying model for mTORC1-mediated regulation of mRNA translation

(2012) Carson C. Thoreen et al.   NATURE

Targeting Quiescent Tumor Cells via Oxygen and IGF-I Supplementation

(2011) A. H. Kyle et al.   CANCER RESEARCH

Cellular IRES-mediated translation

(2011) Anton A Komar et al.   CELL CYCLE

Nuclear signalling by membrane protein intracellular domains: The AICD enigma

(2011) Caroline Beckett et al.   CELLULAR SIGNALLING

Naturally Secreted Amyloid-β Increases Mammalian Target of Rapamycin (mTOR) Activity via a PRAS40-mediated Mechanism

(2011) Antonella Caccamo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypoxia-induced Jagged2 promotes breast cancer metastasis and self-renewal of cancer stem-like cells

(2011) F Xing et al.   ONCOGENE

4E-BP1 Is a Key Effector of the Oncogenic Activation of the AKT and ERK Signaling Pathways that Integrates Their Function in Tumors

(2010) Qing-Bai She et al.   CANCER CELL

Optical imaging of tumor hypoxia dynamics

(2010) Gregory M. Palmer et al.   JOURNAL OF BIOMEDICAL OPTICS

Translational Regulation of Gene Expression during Conditions of Cell Stress

(2010) Keith A. Spriggs et al.   MOLECULAR CELL

Notch-1 stimulates survival of lung adenocarcinoma cells during hypoxia by activating the IGF-1R pathway

(2010) S Eliasz et al.   ONCOGENE

Presenilin-dependent regulated intramembrane proteolysis and γ-secretase activity

(2009) J. V. McCarthy et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

RhoE Inhibits 4E-BP1 Phosphorylation and eIF4E Function Impairing Cap-dependent Translation

(2009) Priam Villalonga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Insulin/Akt Signaling Pathway Is Targeted by Intracellular β-Amyloid

(2009) Han-Kyu Lee et al.   MOLECULAR BIOLOGY OF THE CELL

Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

(2009) Nao Hosokawa et al.   MOLECULAR BIOLOGY OF THE CELL

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL

A TAG1-APP signalling pathway through Fe65 negatively modulates neurogenesis

(2008) Quan-Hong Ma et al.   NATURE CELL BIOLOGY

Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation

(2008) A. Y. Choo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure of the yeast eIF4A-eIF4G complex: An RNA-helicase controlled by protein-protein interactions

(2008) P. Schutz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteomic Profiling of γ-Secretase Substrates and Mapping of Substrate Requirements

(2008) Matthew L Hemming et al.   PLOS BIOLOGY