Resveratrol Increases Anti-Proliferative Activity of Bestatin Through Downregulating P-Glycoprotein Expression Via Inhibiting PI3K/Akt/mTOR Pathway in K562/ADR Cells

Zuo Jin Wan reverses P-gp-mediated drug-resistance by inhibiting activation of the PI3K/Akt/NF-κB pathway

(2014) Hua Sui et al.   BMC Complementary and Alternative Medicine

Dasatinib reverses the multidrug resistance of breast cancer MCF-7 cells to doxorubicin by downregulating P-gp expression via inhibiting the activation of ERK signaling pathway

(2014) Ting Chen et al.   CANCER BIOLOGY & THERAPY

PEPT1- and OAT1/3-mediated drug–drug interactions between bestatin and cefixime in vivo and in vitro in rats, and in vitro in human

(2014) Li Wang et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Enhancement effect of P-gp inhibitors on the intestinal absorption and antiproliferative activity of bestatin

(2013) Xiaokui Huo et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Dioscin Restores the Activity of the Anticancer Agent Adriamycin in Multidrug-Resistant Human Leukemia K562/Adriamycin Cells by Down-Regulating MDR1 via a Mechanism Involving NF-κB Signaling Inhibition

(2013) Lijuan Wang et al.   JOURNAL OF NATURAL PRODUCTS

Reversion of P-Glycoprotein-Mediated Multidrug Resistance in Human Leukemic Cell Line by Diallyl Trisulfide

(2012) Qing Xia et al.   Evidence-based Complementary and Alternative Medicine

The RAS/RAF/MEK/ERK and the PI3K/AKT signalling pathways: role in cancer pathogenesis and implications for therapeutic approaches

(2012) Antonella De Luca et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

The Anticancer Effects of Resveratrol: Modulation of Transcription Factors

(2012) Nichelle C. Whitlock et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Chemosensitization of tumors by resveratrol

(2011) Subash C. Gupta et al.   Annals of the New York Academy of Sciences

3β-acetyl tormentic acid induces apoptosis of resistant leukemia cells independently of P-gp/ABCB1 activity or expression

(2010) Gleice da Graça Rocha et al.   INVESTIGATIONAL NEW DRUGS

An Intracellular Signal Pathway That Regulates Cancer Cell Adhesion in Response to Extracellular Forces

(2008) M. D. Basson   CANCER RESEARCH

The novel Akt inhibitor, perifosine, induces caspase-dependent apoptosis and downregulates P-glycoprotein expression in multidrug-resistant human T-acute leukemia cells by a JNK-dependent mechanism

(2008) F Chiarini et al.   LEUKEMIA