The P2RY2 Receptor Induces Carcinoma Cell Migration and EMT Through Cross-Talk With Epidermal Growth Factor Receptor

Breast cancer stem cells, EMT and therapeutic targets

(2014) Srishti Kotiyal et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The activation of P2Y2 receptors increases MCF-7 breast cancer cells migration through the MEK-ERK1/2 signalling pathway

(2014) Stéphanie Chadet et al.   CARCINOGENESIS

P2Y2R activation by nucleotides promotes skin wound-healing process

(2014) Hana Jin et al.   EXPERIMENTAL DERMATOLOGY

The P2Y2Nucleotide Receptor Mediates the Proliferation and Migration of Human Hepatocellular Carcinoma Cells Induced by ATP

(2014) Rui Xie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ErbB targeting inhibitors repress cell migration of esophageal squamous cell carcinoma and adenocarcinoma cells by distinct signaling pathways

(2014) Christiane D. Fichter et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Uridine 5′-Triphosphate Promotes In Vitro Schwannoma Cell Migration through Matrix Metalloproteinase-2 Activation

(2014) Aloa Lamarca et al.   PLoS One

IL-4 type 1 receptor signaling up-regulates KCNN4 expression, and increases the KCa3.1 current and its contribution to migration of alternative-activated microglia

(2014) Roger Ferreira et al.   Frontiers in Cellular Neuroscience

Epithelial Wounds Induce Differential Phosphorylation Changes in Response to Purinergic and EGF Receptor Activation

(2013) Amanuel Kehasse et al.   AMERICAN JOURNAL OF PATHOLOGY

P2Y2 receptor promotes cell invasion and metastasis in prostate cancer cells

(2013) W-H Li et al.   BRITISH JOURNAL OF CANCER

An international assessment of ovarian cancer incidence and mortality

(2013) Kimberly A. Lowe et al.   GYNECOLOGIC ONCOLOGY

Targeting Cancer Metabolism

(2012) B. A. Teicher et al.   CLINICAL CANCER RESEARCH

P2 Receptors for Extracellular Nucleotides in the Central Nervous System: Role of P2X7 and P2Y2 Receptor Interactions in Neuroinflammation

(2012) Gary A. Weisman et al.   MOLECULAR NEUROBIOLOGY

Differential expression of the P2X7 receptor in ovarian surface epithelium during the oestrous cycle in the mouse

(2012) F. G. Vázquez-Cuevas et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

GPR30 regulates the EGFR-Akt cascade and predicts lower survival in patients with ovarian cancer

(2012) Satoe Fujiwara et al.   Journal of Ovarian Research

Uridine adenosine tetraphosphate (Up4A) is a strong inductor of smooth muscle cell migration via activation of the P2Y2 receptor and cross-communication to the PDGF receptor

(2011) Annette Wiedon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cancer Stem Cells and Epithelial-to-Mesenchymal Transition (EMT)-Phenotypic Cells: Are They Cousins or Twins?

(2011) Dejuan Kong et al.   Cancers

The P2Y2 receptor mediates the epithelial injury response and cell migration

(2010) Ilene Boucher et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The chemokine CXCL1 induces proliferation in epithelial ovarian cancer cells by transactivation of the epidermal growth factor receptor

(2010) Christine Bolitho et al.   ENDOCRINE-RELATED CANCER

Phenotypic Plasticity of the Ovarian Surface Epithelium: TGF-β1 Induction of Epithelial to Mesenchymal Transition (EMT)in Vitro

(2010) Yihong Zhu et al.   ENDOCRINOLOGY

P2Y2Nucleotide Receptors Mediate Metalloprotease-dependent Phosphorylation of Epidermal Growth Factor Receptor and ErbB3 in Human Salivary Gland Cells

(2010) Ann M. Ratchford et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Basal Release of ATP: An Autocrine-Paracrine Mechanism for Cell Regulation

(2010) R. Corriden et al.   Science Signaling

Epithelial-Mesenchymal Transitions in development and disease: old views and new perspectives

(2009) M. Angela Nieto   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease

(2009) Hervé Acloque et al.   JOURNAL OF CLINICAL INVESTIGATION

Endothelial P2Y2 receptor regulates LPS-induced neutrophil transendothelial migration in vitro

(2009) Filip Kukulski et al.   MOLECULAR IMMUNOLOGY

Cross talk of signals between EGFR and IL-6R through JAK2/STAT3 mediate epithelial–mesenchymal transition in ovarian carcinomas

(2008) M Colomiere et al.   BRITISH JOURNAL OF CANCER

Implications of EGFR inhibition in ovarian cancer cell proliferation

(2008) Shawna L. Bull Phelps et al.   GYNECOLOGIC ONCOLOGY

Increased Level of Extracellular ATP at Tumor Sites: In Vivo Imaging with Plasma Membrane Luciferase

(2008) Patrizia Pellegatti et al.   PLoS One

Crosstalk between G-protein-coupled receptors and Epidermal growth factor receptor in cancer

(2007) Neil et al.   Frontiers in Bioscience-Landmark