The RUNX2 Transcription Factor Negatively Regulates SIRT6 Expression to Alter Glucose Metabolism in Breast Cancer Cells

Oncogenic cooperation between PI3K/Akt signaling and transcription factor Runx2 promotes the invasive properties of metastatic breast cancer cells

(2013) Sandhya Pande et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The Histone Deacetylase SIRT6 Is a Tumor Suppressor that Controls Cancer Metabolism

(2012) Carlos Sebastián et al.   CELL

RUNX2 in mammary gland development and breast cancer

(2012) Nicola Ferrari et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Investigation of Mitochondrial Dysfunction by Sequential Microplate-Based Respiration Measurements from Intact and Permeabilized Neurons

(2012) Pascaline Clerc et al.   PLoS One

Tumor initiating but differentiated luminal-like breast cancer cells are highly invasive in the absence of basal-like activity

(2012) J. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional repression of RUNX2 is associated with aggressive clinicopathological outcomes, whereas nuclear location of the protein is related to metastasis in prostate cancer

(2012) S J Yun et al.   PROSTATE CANCER AND PROSTATIC DISEASES

ERα, microRNAs, and the epithelial–mesenchymal transition in breast cancer

(2012) Irene K. Guttilla et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Prolonged mammosphere culture of MCF-7 cells induces an EMT and repression of the estrogen receptor by microRNAs

(2011) I. K. Guttilla et al.   BREAST CANCER RESEARCH AND TREATMENT

Molecular biology in breast cancer: Intrinsic subtypes and signaling pathways

(2011) Pilar Eroles et al.   CANCER TREATMENT REVIEWS

Reduced activity and cytoplasmic localization of Runx2 is observed in C3h10t1/2 cells overexpressing Tbx3

(2011) Vishwa Deepak et al.   CELL BIOCHEMISTRY AND FUNCTION

Opposing Effects of Runx2 and Estradiol on Breast Cancer Cell Proliferation: In Vitro Identification of Reciprocally Regulated Gene Signature Related to Clinical Letrozole Responsiveness

(2011) N.-O. Chimge et al.   CLINICAL CANCER RESEARCH

UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells

(2011) Jin Zhang et al.   EMBO JOURNAL

Regulation of RUNX2 transcription factor-DNA interactions and cell proliferation by vitamin D3 (cholecalciferol) prohormone activity

(2011) Karen F Underwood et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Physical and functional interactions between Runx2 and HIF-1α induce vascular endothelial growth factor gene expression

(2011) Tae-Geon Kwon et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Glucose-activated RUNX2 phosphorylation promotes endothelial cell proliferation and an angiogenic phenotype

(2011) Adam D. Pierce et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

SIRT6 Promotes DNA Repair Under Stress by Activating PARP1

(2011) Z. Mao et al.   SCIENCE

Premalignant Breast Neoplasia: A Paradigm of Interlesional and Intralesional Molecular Heterogeneity and Its Biological and Clinical Ramifications

(2010) H. K. Berman et al.   Cancer Prevention Research

Runx2 in human breast carcinoma: its potential roles in cancer progression

(2010) Yoshiaki Onodera et al.   CANCER SCIENCE

The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1α

(2010) Lei Zhong et al.   CELL

Mitochondrial reserve capacity in endothelial cells: The impact of nitric oxide and reactive oxygen species

(2010) Brian P. Dranka et al.   FREE RADICAL BIOLOGY AND MEDICINE

Complex Display of Putative Tumor Stem Cell Markers in the NCI60 Tumor Cell Line Panel

(2010) Christina H. Stuelten et al.   STEM CELLS

Breast Cancer Cell Lines Contain Functional Cancer Stem Cells with Metastatic Capacity and a Distinct Molecular Signature

(2009) Emmanuelle Charafe-Jauffret et al.   CANCER RESEARCH

Positive association between nuclear Runx2 and oestrogen-progesterone receptor gene expression characterises a biological subtype of breast cancer

(2009) Kakoli Das et al.   EUROPEAN JOURNAL OF CANCER

Hyperglycemia Regulates RUNX2 Activation and Cellular Wound Healing through the Aldose Reductase Polyol Pathway

(2009) David R. D'Souza et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification and Functional Characterization of ERK/MAPK Phosphorylation Sites in the Runx2 Transcription Factor

(2009) Chunxi Ge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

TGFβ in Cancer

(2008) Joan Massagué   CELL

Characterisation of breast cancer cell lines and establishment of a novel isogenic subclone to study migration, invasion and tumourigenicity

(2008) Linda Hughes et al.   CLINICAL & EXPERIMENTAL METASTASIS

Epithelial mesenchymal transition traits in human breast cancer cell lines

(2008) T. Blick et al.   CLINICAL & EXPERIMENTAL METASTASIS

Regulation of SIRT6 protein levels by nutrient availability

(2008) Yariv Kanfi et al.   FEBS LETTERS

Regulation of cancer cell metabolism by hypoxia-inducible factor 1

(2008) Gregg L. Semenza   SEMINARS IN CANCER BIOLOGY

Reciprocal regulation of bone and energy metabolism

(2008) Na Kyung Lee et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM