Mammary Branching Morphogenesis Requires Reciprocal Signaling by Heparanase and MMP-14

SnapShot: Branching Morphogenesis

(2014) Cheng-Ming Chuong et al.   CELL

The hemopexin domain of MMP3 is responsible for mammary epithelial invasion and morphogenesis through extracellular interaction with HSP90 

(2013) A. L. Correia et al.   GENES & DEVELOPMENT

Laser Scanning–Based Tissue Autofluorescence/Fluorescence Imaging (LS-TAFI), a New Technique for Analysis of Microanatomy in Whole-Mount Tissues

(2012) Hidetoshi Mori et al.   AMERICAN JOURNAL OF PATHOLOGY

Transmembrane/cytoplasmic, rather than catalytic, domains of Mmp14 signal to MAPK activation and mammary branching morphogenesis via binding to integrin  1

(2012) H. Mori et al.   DEVELOPMENT

Constructing Three-Dimensional Models to Study Mammary Gland Branching Morphogenesis and Functional Differentiation

(2012) Alvin T. Lo et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Accelerated Resolution of AA Amyloid in Heparanase Knockout Mice Is Associated with Matrix Metalloproteases

(2012) Bo Wang et al.   PLoS One

Stage-dependent regulation of mammary ductal branching by heparan sulfate and HGF-cMet signaling

(2011) Omai B. Garner et al.   DEVELOPMENTAL BIOLOGY

Collective epithelial cell invasion overcomes mechanical barriers of collagenous extracellular matrix by a narrow tube-like geometry and MMP14-dependent local softening

(2011) Jordi Alcaraz et al.   Integrative Biology

Newly Generated Heparanase Knock-Out Mice Unravel Co-Regulation of Heparanase and Matrix Metalloproteinases

(2009) Eyal Zcharia et al.   PLoS One

Differential Interactions of FGFs with Heparan Sulfate Control Gradient Formation and Branching Morphogenesis

(2009) H. P. Makarenkova et al.   Science Signaling

Collective Epithelial Migration and Cell Rearrangements Drive Mammary Branching Morphogenesis

(2008) Andrew J. Ewald et al.   DEVELOPMENTAL CELL

Heparanase Stimulation of Protease Expression Implicates It as a Master Regulator of the Aggressive Tumor Phenotype in Myeloma

(2008) Anurag Purushothaman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY