Fascaplysin Induces Caspase Mediated Crosstalk Between Apoptosis and Autophagy Through the Inhibition of PI3K/AKT/mTOR Signaling Cascade in Human Leukemia HL-60 Cells

Autophagy plays a protective role during zVAD-induced necrotic cell death

(2014) You-Tong Wu et al.   Autophagy

Tiron and trolox potentiate the autophagic cell death induced by magnolol analog Ery5 by activation of Bax in HL-60 cells

(2013) Suresh Kumar et al.   APOPTOSIS

Autophagy triggered by magnolol derivative negatively regulates angiogenesis

(2013) S Kumar et al.   Cell Death & Disease

Anticancer activity, toxicity and pharmacokinetic profile of an indanone derivative

(2012) Debabrata Chanda et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Chemistry and Biology of Fascaplysin, a Potent Marine-Derived CDK-4 Inhibitor

(2012) S. B. Bharate et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Total synthesis and anti-cholinesterase activity of marine-derived bis-indole alkaloid fascaplysin

(2012) Sandip B. Bharate et al.   MedChemComm

PARP and RIP 1 are required for autophagy induced by 11'-deoxyverticillin A, which precedes caspase-dependent apoptosis

(2011) Nan Zhang et al.   Autophagy

Quercetin induces protective autophagy in gastric cancer cells: Involvement of Akt-mTOR- and hypoxia-induced factor 1α-mediated signaling

(2011) Kui Wang et al.   Autophagy

Fascaplysin exert anti-tumor effects through apoptotic and anti-angiogenesis pathways in sarcoma mice model

(2011) Xiaojun Yan et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Cannabidiol Induces Programmed Cell Death in Breast Cancer Cells by Coordinating the Cross-talk between Apoptosis and Autophagy

(2011) A. Shrivastava et al.   MOLECULAR CANCER THERAPEUTICS

The PI3K Pathway As Drug Target in Human Cancer

(2010) Kevin D. Courtney et al.   JOURNAL OF CLINICAL ONCOLOGY

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

Activation of the PI3K/Akt Pathway Early during Vaccinia and Cowpox Virus Infections Is Required for both Host Survival and Viral Replication

(2009) J. A. P. Soares et al.   JOURNAL OF VIROLOGY

Programmed cell death and cancer

(2009) Y Sun et al.   POSTGRADUATE MEDICAL JOURNAL

Endothelial p70 S6 Kinase 1 in Regulating Tumor Angiogenesis

(2008) L.-Z. Liu et al.   CANCER RESEARCH

PI3K/AKT inhibition induces caspase-dependent apoptosis in HTLV-1-transformed cells

(2007) Soo-Jin Jeong et al.   VIROLOGY