Spp24 Derivatives Stimulate a Gi-Protein Coupled Receptor-Erk1/2 Signaling Pathway and Modulate Gene Expressions in W-20-17 Cells

Regulation of TGFβ and related signals by precursor processing

(2014) Daniel B. Constam   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Food-intake dysregulation in type 2 diabetic Goto-Kakizaki rats: Hypothesized role of dysfunctional brainstem thyrotropin-releasing hormone and impaired vagal output

(2013) K. Zhao et al.   NEUROSCIENCE

MEROPS: the database of proteolytic enzymes, their substrates and inhibitors

(2013) Neil D. Rawlings et al.   NUCLEIC ACIDS RESEARCH

Secreted Phosphoprotein 24 kD (Spp24) and Spp14 Affect TGF-β Induced Bone Formation Differently

(2013) Haijun Tian et al.   PLoS One

Secreted phosphoprotein-24 kDa (Spp24) attenuates BMP-2-stimulated Smad 1/5 phosphorylation and alkaline phosphatase induction and was purified in a protective complex with alpha2-Macroglobulins From Serum

(2012) Ke-Wei Zhao et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

What lies ahead for the proprotein convertases?

(2011) Nabil G. Seidah   Annals of the New York Academy of Sciences

Full-Length spp24, but Not Its 18.5-kDa Proteolytic Fragment, Inhibits Bone-Healing in a Rodent Model of Spine Fusion

(2011) Chananit Sintuu et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Interactions between extracellular signal-regulated kinase 1/2 and P38 Map kinase pathways in the control of RUNX2 phosphorylation and transcriptional activity

(2011) Chunxi Ge et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Effects of the bone morphogenetic protein binding protein spp24 (secreted phosphoprotein 24 kD) on the growth of human lung cancer cells

(2011) Kwang-Bok Lee et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Bone morphogenetic protein–binding peptide reduces the inflammatory response to recombinant human bone morphogenetic protein-2 and recombinant human bone morphogenetic protein-7 in a rodent model of soft-tissue inflammation

(2011) Kwang-Bok Lee et al.   Spine Journal

Alanine-scanning mutations of the BMP-binding domain of recombinant secretory bovine spp24 affect cytokine binding

(2010) Argus Sun et al.   CONNECTIVE TISSUE RESEARCH

BMP2-activated Erk/MAP Kinase Stabilizes Runx2 by Increasing p300 Levels and Histone Acetyltransferase Activity

(2010) Ji Hae Jun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Attenuation of AH26-Induced Apoptosis by Inhibition of SAPK/JNK Pathway in MC-3T3 E1 Cells

(2010) Mi-Kyung Yu et al.   JOURNAL OF ENDODONTICS

Carboxy terminus of secreted phosphoprotein-24 kDa (spp24) is essential for full inhibition of BMP-2 activity

(2010) Elsa J. Brochmann et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Bone Morphogenetic Protein Binding Peptide Mechanism and Enhancement of Osteogenic Protein-1 Induced Bone Healing

(2010) Cyrus E. Taghavi et al.   SPINE

Phylogenomic analysis of the cystatin superfamily in eukaryotes and prokaryotes

(2009) Dušan Kordiš et al.   BMC EVOLUTIONARY BIOLOGY

Bone morphogenetic protein–2 activity is regulated by secreted phosphoprotein–24 kd, an extracellular pseudoreceptor, the gene for which maps to a region of the human genome important for bone quality

(2009) Elsa J. Brochmann et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Differences in matrix composition between calvaria and long bone in mice suggest differences in biomechanical properties and resorption

(2008) T. van den Bos et al.   BONE

Transcriptional Regulation of Osteoblasts

(2008) Renny T. Franceschi et al.   CELLS TISSUES ORGANS

Full-length bovine spp24 [spp24 (24-203)] inhibits BMP-2 induced bone formation

(2008) Chananit Sintuu et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

The Adjunctive Effect of a Binding Peptide on Bone Morphogenetic Protein Enhanced Bone Healing in a Rodent Model of Spinal Fusion

(2008) Ahmet Alanay et al.   SPINE