Early Growth Response Protein-1 Expression by Insulin-Like Growth Factor-1 Requires ROS-Dependent Activation of ERK1/2 and PKB Pathways in Vascular Smooth Muscle Cells

Apelin-13-induced proliferation and migration induced of rat vascular smooth muscle cells is mediated by the upregulation of Egr-1

(2013) Qi-Feng Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Recruitment of Nox4 to a Plasma Membrane Scaffold Is Required for Localized Reactive Oxygen Species Generation and Sustained Src Activation in Response to Insulin-like Growth Factor-I

(2013) Gang Xi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of Egr-1 in Human Lung Epithelial Cells Exposed to Silica through MAPKs Signaling Pathways

(2013) Ling Chu et al.   PLoS One

Attenuation of endothelin-1-induced PKB and ERK1/2 signaling, as well as Egr-1 expression, by curcumin in A-10 vascular smooth muscle cells

(2012) Georgia Kapakos et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Insulin-like growth-factor-1-induced PKB signaling and Egr-1 expression is inhibited by curcumin in A-10 vascular smooth muscle cells

(2012) Viktoria Youreva et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Lysophosphatidic Acid Induces Early Growth Response-1 (Egr-1) Protein Expression via Protein Kinase Cδ-regulated Extracellular Signal-regulated Kinase (ERK) and c-Jun N-terminal Kinase (JNK) Activation in Vascular Smooth Muscle Cells

(2012) Takuya Iyoda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Curcumin inhibits proliferation of human lens epithelial cells: a proteomic analysis

(2012) Yan-hong Hu et al.   Journal of Zhejiang University-SCIENCE B

Aging, Atherosclerosis, and IGF-1

(2012) Y. Higashi et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Role of early growth response 1 in arteriogenesis: Impact on vascular cell proliferation and leukocyte recruitment in vivo

(2012) Tibor Ziegelhoeffer et al.   THROMBOSIS AND HAEMOSTASIS

Mechanical stretch augments insulin-induced vascular smooth muscle cell proliferation by insulin-like growth factor-1 receptor

(2011) Gang Liu et al.   EXPERIMENTAL CELL RESEARCH

Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma

(2011) Reason Wilken et al.   Molecular Cancer

Xanthine Oxidase-Derived ROS Upregulate Egr-1 via ERK1/2 in PA Smooth Muscle Cells; Model to Test Impact of Extracellular ROS in Chronic Hypoxia

(2011) Tanya Hartney et al.   PLoS One

Deactivation of Akt by a small molecule inhibitor targeting pleckstrin homology domain and facilitating Akt ubiquitination

(2011) H. Jo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Involvement of insulin-like growth factor 1 receptor transactivation in endothelin-1-induced signaling in vascular smooth muscle cells

(2010) Ali Bouallegue et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Enhanced levels of endogenous endothelin-1 contribute to the over expression of Giα protein in vascular smooth muscle cells from SHR: Role of growth factor receptor activation

(2010) Yessica-Haydee Gomez Sandoval et al.   CELLULAR SIGNALLING

Insulin-like growth factor-1 induces phosphorylation of PI3K-Akt/PKB to potentiate proliferation of smooth muscle cells in human saphenous vein

(2010) Guanghong Jia et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Cross-talk between angiotensin II and IGF-1-induced connexin 43 expression in human saphenous vein smooth muscle cells

(2010) Guanghong Jia et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Mechano-Sensitive Transcriptional Factor Egr-1 Regulates Insulin-Like Growth Factor-1 Receptor Expression and Contributes to Neointima Formation in Vein Grafts

(2009) Xiaoqian Wu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Role of insulin-like growth factor 1 receptor and c-Src in endothelin-1- and angiotensin II-induced PKB phosphorylation, and hypertrophic and proliferative responses in vascular smooth muscle cellsThis article is one of a selection of papers published in a special issue on Advances in Cardiovascular Research.

(2009) Ali Bouallegue et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

N-4-Tert-Butyl Benzyl Haloperidol Chloride Suppresses Ca2+-dependent Egr-1 Expression and Subsequently Inhibits Vascular Smooth Muscle Cell Proliferation Induced by Angiotensin II

(2009) Yicun Chen et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

c-Jun Regulates Shear- and Injury-inducible Egr-1 Expression, Vein Graft Stenosis after Autologous End-to-Side Transplantation in Rabbits, and Intimal Hyperplasia in Human Saphenous Veins

(2009) Jun Ni et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

EGR-1 decoy ODNs inhibit vascular smooth muscle cell proliferation and neointimal hyperplasia of balloon-injured arteries in rat

(2009) Wei Han et al.   LIFE SCIENCES

The Insulin-Like Growth Factor Family: Molecular Mechanisms, Redox Regulation, and Clinical Implications

(2008) George Vardatsikos et al.   ANTIOXIDANTS & REDOX SIGNALING

Insulin-like growth factor-I induces reactive oxygen species production and cell migration through Nox4 and Rac1 in vascular smooth muscle cells

(2008) D. Meng et al.   CARDIOVASCULAR RESEARCH

Antioxidant and radical scavenging properties of curcumin

(2008) Tuba Ak et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Insulin-like Growth Factor-I Stimulates Shc-dependent Phosphatidylinositol 3-Kinase Activation via Grb2-associated p85 in Vascular Smooth Muscle Cells

(2008) Yashwanth Radhakrishnan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Convergence of integrins and EGF receptor signaling via PI3K/Akt/FoxO pathway in early gene Egr-1 expression

(2008) Sara Cabodi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Hemin Upregulates Egr-1 Expression in Vascular Smooth Muscle Cells via Reactive Oxygen Species ERK-1/2–Elk-1 and NF-κB

(2007) Rukhsana N. Hasan et al.   CIRCULATION RESEARCH