The Role of Jak/STAT Pathways in Osteoclast Differentiation

Inhibition of T cell-dependent and RANKL-dependent osteoclastogenic processes associated with high levels of bone mass in interleukin-15 receptor-deficient mice

(2010) Souad Djaafar et al.   ARTHRITIS AND RHEUMATISM

IL-3 Inhibits Human Osteoclastogenesis and Bone Resorption through Downregulation of c-Fms and Diverts the Cells to Dendritic Cell Lineage

(2010) N. Gupta et al.   JOURNAL OF IMMUNOLOGY

Bisphosphonates for Osteoporosis

(2010) Murray J. Favus   NEW ENGLAND JOURNAL OF MEDICINE

Identification of cell cycle–arrested quiescent osteoclast precursors in vivo

(2009) Toshihide Mizoguchi et al.   JOURNAL OF CELL BIOLOGY

PIAS3 negatively regulates RANKL-mediated osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblasts

(2008) T. Hikata et al.   BLOOD

Interleukin-6 Inhibits Receptor Activator of Nuclear Factor κB Ligand-Induced Osteoclastogenesis by Diverting Cells into the Macrophage Lineage: Key Role of Serine727Phosphorylation of Signal Transducer and Activator of Transcription 3

(2008) Laurence Duplomb et al.   ENDOCRINOLOGY

Interleukin-6 Directly Inhibits Osteoclast Differentiation by Suppressing Receptor Activator of NF-κB Signaling Pathways

(2008) Fumio Yoshitake et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Atp6v0d2 Is an Essential Component of the Osteoclast-Specific Proton Pump That Mediates Extracellular Acidification in Bone Resorption

(2008) Haiping Wu et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Osteoporosis: overview and pipeline

(2008) Uma Yasothan et al.   NATURE REVIEWS DRUG DISCOVERY

The ubiquitin-mediated degradation of Jak1 modulates osteoclastogenesis by limiting interferon- induced inhibitory signaling

(2007) Y. Lee et al.   BLOOD