Journal
BIOMICROFLUIDICS
Volume 4, Issue 4, Pages -Publisher
AMER INST PHYSICS
DOI: 10.1063/1.3523471
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Funding
- Ministry of Education, Culture, Sports, Science, and Technology of Japan
- Japan Society for the Promotion of Science [17076015, 18206027, 214059]
- Grants-in-Aid for Scientific Research [18206027, 17076015] Funding Source: KAKEN
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We proposed and fabricated multiscale transparent arteriole and capillary vessel models with circular cross sections of 10-500 mu m using photolithography. The circularities of the fabricated 10, 50, and 500 mu m diameter microchannels were 84.0%, 61.5%, and 82.3%, respectively. Next, we connected these different models to realize a circulation type blood vessel model simulating arteriole networks. We proposed a novel connection method using an intermediate connector made of wax, which we used to connect these models to make a circulation model. In flow experiments, the fabricated models showed no leakage and circulation models with seamless connections were achieved. (C) 2010 American Institute of Physics. [doi:10.1063/1.3523471]
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