Belinostat, a potent HDACi, exerts antileukaemic effect in human acute promyelocytic leukaemia cellsviachromatin remodelling

Epigenetic and molecular mechanisms underlying the antileukemic activity of the histone deacetylase inhibitor belinostat in human acute promyelocytic leukemia cells

(2014) Jurate Savickiene et al.   ANTI-CANCER DRUGS

Belinostat-induced apoptosis and growth inhibition in pancreatic cancer cells involve activation of TAK1-AMPK signaling axis

(2013) Bing Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Klebsiella Phage vB_KleM-RaK2 — A Giant Singleton Virus of the Family Myoviridae

(2013) Eugenijus Šimoliūnas et al.   PLoS One

NETs: the missing link between cell death and systemic autoimmune diseases?

(2013) Erika Darrah et al.   Frontiers in Immunology

Role of Hydroxamate-Based Histone Deacetylase Inhibitors (Hb-HDACIs) in the Treatment of Solid Malignancies

(2013) Antonino Grassadonia et al.   Cancers

New Insights into the Regulation of Neutrophil NADPH Oxidase Activity in the Phagosome: A Focus on the Role of Lipid and Ca2+ Signaling

(2012) Sabrina Bréchard et al.   ANTIOXIDANTS & REDOX SIGNALING

A phase II evaluation of belinostat and carboplatin in the treatment of recurrent or persistent platinum-resistant ovarian, fallopian tube, or primary peritoneal carcinoma: A gynecologic oncology group study

(2012) Don S. Dizon et al.   GYNECOLOGIC ONCOLOGY

Phase II Activity of Belinostat (PXD-101), Carboplatin, and Paclitaxel in Women With Previously Treated Ovarian Cancer

(2012) Don S. Dizon et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Epigenetic Therapy Using Belinostat for Patients With Unresectable Hepatocellular Carcinoma: A Multicenter Phase I/II Study With Biomarker and Pharmacokinetic Analysis of Tumors From Patients in the Mayo Phase II Consortium and the Cancer Therapeutics Research Group

(2012) Winnie Yeo et al.   JOURNAL OF CLINICAL ONCOLOGY

Infection-induced NETosis is a dynamic process involving neutrophil multitasking in vivo

(2012) Bryan G Yipp et al.   NATURE MEDICINE

Bortezomib interacts synergistically with belinostat in human acute myeloid leukaemia and acute lymphoblastic leukaemia cells in association with perturbations in NF-κB and Bim

(2011) Yun Dai et al.   BRITISH JOURNAL OF HAEMATOLOGY

Dying for a cause: NETosis, mechanisms behind an antimicrobial cell death modality

(2011) Q Remijsen et al.   CELL DEATH AND DIFFERENTIATION

Phase II Study of Belinostat in Patients With Recurrent or Refractory Advanced Thymic Epithelial Tumors

(2011) Giuseppe Giaccone et al.   JOURNAL OF CLINICAL ONCOLOGY

Genomic DNA Hypomethylation by Histone Deacetylase Inhibition Implicates DNMT1 Nuclear Dynamics

(2011) M. K. Arzenani et al.   MOLECULAR AND CELLULAR BIOLOGY

C/EBPα and PU.1 are involved in distinct differentiation responses of acute promyelocytic leukemia HL-60 and NB4 cells via chromatin remodeling

(2010) Jurate Savickiene et al.   DIFFERENTIATION

Expression of S100A8/A9 in HaCaT keratinocytes alters the rate of cell proliferation and differentiation

(2010) Andreas Voss et al.   FEBS LETTERS

Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps

(2010) Venizelos Papayannopoulos et al.   JOURNAL OF CELL BIOLOGY

Phase II Study of Belinostat (PXD101), a Histone Deacetylase Inhibitor, for Second Line Therapy of Advanced Malignant Pleural Mesothelioma

(2010) Suresh S. Ramalingam et al.   Journal of Thoracic Oncology

Enhanced Expression of PCAF Endows Apoptosis Resistance in Cisplatin-Resistant Cells

(2010) G. Hirano et al.   MOLECULAR CANCER RESEARCH

Viable neutrophils release mitochondrial DNA to form neutrophil extracellular traps

(2009) S Yousefi et al.   CELL DEATH AND DIFFERENTIATION

Therapy-induced PML/RARA Proteolysis and Acute Promyelocytic Leukemia Cure

(2009) R. Nasr et al.   CLINICAL CANCER RESEARCH

Expression Levels of Histone Deacetylases Determine the Cell Fate of Hematopoietic Progenitors

(2009) Taeko Wada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation

(2009) Yanming Wang et al.   JOURNAL OF CELL BIOLOGY

Universal sample preparation method for proteome analysis

(2009) Jacek R Wiśniewski et al.   NATURE METHODS

Neutrophil Extracellular Traps Contain Calprotectin, a Cytosolic Protein Complex Involved in Host Defense against Candida albicans

(2009) Constantin F. Urban et al.   PLoS Pathogens

Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors

(2008) Nagma Khan et al.   BIOCHEMICAL JOURNAL