Journal
BIOMETALS
Volume 23, Issue 6, Pages 1015-1028Publisher
SPRINGER
DOI: 10.1007/s10534-010-9347-8
Keywords
Phthalylsulfathiazole; Sulfadrugs metal complexes; Cobalt complexes; Antifungal properties; Antibacterial properties
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Funding
- Rosario National University
- National Research Council of Argentina (CONICET)
- Fundacion Prats
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The reaction between phthalylsulfathiazole (H2PST), in alkaline aqueous solution, and cobalt(II) nitrate led to a pink solid, [Co(PST)(H2O)(4)] (1), which was characterized by elemental and thermogravimetric analysis; FT-IR, Raman and diffuse reflectance spectra. Spectroscopic data reveal that the ligand would be doubly deprotonated and that the Co(II) ion environment is a distorted octahedral one. (1) showed antibacterial activity similar to the ligand.
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