A novel role of farnesylation in targeting a mitotic checkpoint protein, human Spindly, to kinetochores

Spindle assembly checkpoint proteins are positioned close to core microtubule attachment sites at kinetochores

(2013) Dileep Varma et al.   JOURNAL OF CELL BIOLOGY

Lonafarnib for cancer and progeria

(2012) Nan Soon Wong et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Multi-institutional phase 2 clinical and pharmacogenomic trial of tipifarnib plus etoposide for elderly adults with newly diagnosed acute myelogenous leukemia

(2011) J. E. Karp et al.   BLOOD

Spindly switch controls anaphase: Spindly and RZZ functions in chromosome attachment and mitotic checkpoint control

(2011) Marin Barisic et al.   CELL CYCLE

Regulating the regulator: post-translational modification of RAS

(2011) Ian M. Ahearn et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

PhosphoSitePlus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse

(2011) P. V. Hornbeck et al.   NUCLEIC ACIDS RESEARCH

Dynein/Dynactin-Mediated Transport of Kinetochore Components off Kinetochores and onto Spindle Poles Induced by Nordihydroguaiaretic Acid

(2011) Jakub K. Famulski et al.   PLoS One

Protein farnesylation inhibitors cause donut-shaped cell nuclei attributable to a centrosome separation defect

(2011) V. L. R. M. Verstraeten et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Removal of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cells

(2010) R. Gassmann et al.   GENES & DEVELOPMENT

Spindly/CCDC99 Is Required for Efficient Chromosome Congression and Mitotic Checkpoint Regulation

(2010) Marin Barisic et al.   MOLECULAR BIOLOGY OF THE CELL

Alkynyl-farnesol reporters for detection ofproteinS-prenylation in cells

(2010) Guillaume Charron et al.   Molecular BioSystems

Structural Analysis of the RZZ Complex Reveals Common Ancestry with Multisubunit Vesicle Tethering Machinery

(2010) Filiz Çivril et al.   STRUCTURE

Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly

(2009) Ying Wai Chan et al.   JOURNAL OF CELL BIOLOGY

A new mechanism controlling kinetochore-microtubule interactions revealed by comparison of two dynein-targeting components: SPDL-1 and the Rod/Zwilch/Zw10 complex

(2008) R. Gassmann et al.   GENES & DEVELOPMENT

Stable hZW10 kinetochore residency, mediated by hZwint-1 interaction, is essential for the mitotic checkpoint

(2008) Jakub K. Famulski et al.   JOURNAL OF CELL BIOLOGY

Ras oncogenes: split personalities

(2008) Antoine E. Karnoub et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY