Altering nuclear pore complex function impacts longevity and mitochondrial function inS. cerevisiae

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Identification of Long-Lived Proteins Reveals Exceptional Stability of Essential Cellular Structures

(2013) Brandon H. Toyama et al.   CELL

The transmission of nuclear pore complexes to daughter cells requires a cytoplasmic pool of Nsp1

(2013) Paolo Colombi et al.   JOURNAL OF CELL BIOLOGY

Inheritance of yeast nuclear pore complexes requires the Nsp1p subcomplex

(2013) Tadashi Makio et al.   JOURNAL OF CELL BIOLOGY

Defective nuclear import of Tpr in Progeria reflects the Ran sensitivity of large cargo transport

(2013) Chelsi J. Snow et al.   JOURNAL OF CELL BIOLOGY

A novel single-cell screening platform reveals proteome plasticity during yeast stress responses

(2013) Michal Breker et al.   JOURNAL OF CELL BIOLOGY

Identification of mitochondrial dysfunction in Hutchinson–Gilford progeria syndrome through use of stable isotope labeling with amino acids in cell culture

(2013) José Rivera-Torres et al.   Journal of Proteomics

The Permeability of Reconstituted Nuclear Pores Provides Direct Evidence for the Selective Phase Model

(2012) Bastian B. Hülsmann et al.   CELL

Yeast as a model to understand the interaction between genotype and the response to calorie restriction

(2012) Jennifer Schleit et al.   FEBS LETTERS

An early age increase in vacuolar pH limits mitochondrial function and lifespan in yeast

(2012) Adam L. Hughes et al.   NATURE

Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress

(2012) Johnny M. Tkach et al.   NATURE CELL BIOLOGY

Prion formation by a yeast GLFG nucleoporin

(2012) Randal Halfmann et al.   Prion

Spatiotemporal analysis of organelle and macromolecular complex inheritance

(2012) V. Menendez-Benito et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extremely Long-Lived Nuclear Pore Proteins in the Rat Brain

(2012) J. N. Savas et al.   SCIENCE

Phosphorylation of Nup98 by Multiple Kinases Is Crucial for NPC Disassembly during Mitotic Entry

(2011) Eva Laurell et al.   CELL

Probing the nucleoporin FG repeat network defines structural and functional features of the nuclear pore complex

(2011) Philipp Stelter et al.   JOURNAL OF CELL BIOLOGY

The Defective Nuclear Lamina in Hutchinson-Gilford Progeria Syndrome Disrupts the Nucleocytoplasmic Ran Gradient and Inhibits Nuclear Localization of Ubc9

(2011) J. B. Kelley et al.   MOLECULAR AND CELLULAR BIOLOGY

The Nuclear Pore Complex and Nuclear Transport

(2010) S. R. Wente et al.   Cold Spring Harbor Perspectives in Biology

Age-Dependent Deterioration of Nuclear Pore Complexes Causes a Loss of Nuclear Integrity in Postmitotic Cells

(2009) Maximiliano A. D'Angelo et al.   CELL

Measuring Replicative Life Span in the Budding Yeast

(2009) Kristan K. Steffen et al.   Jove-Journal of Visualized Experiments

Replicative Aging in Yeast: The Means to the End

(2008) K.A. Steinkraus et al.   Annual Review of Cell and Developmental Biology

Yeast Life Span Extension by Depletion of 60S Ribosomal Subunits Is Mediated by Gcn4

(2008) Kristan K. Steffen et al.   CELL

Arx1 Is a Nuclear Export Receptor for the 60S Ribosomal Subunit in Yeast

(2007) Nai-Jung Hung et al.   MOLECULAR BIOLOGY OF THE CELL