Review
Medicine, General & Internal
Dmitriy Viderman, Karina Tapinova, Fatima Nabidollayeva, Ramil Tankacheev, Yerkin G. Abdildin
Summary: This study compares the use of intravenous and epidural routes for patient-controlled analgesia in abdominal surgery. The results show that there is no significant difference in pain control and side effects between the two methods. However, epidural analgesia is associated with a shorter length of hospital stay, while intravenous analgesia is associated with fewer episodes of hypotension.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Obstetrics & Gynecology
Haibing Li, Hui Li, Yibing Yu, Yan Lu
Summary: This study investigates the safety and efficacy of remifentanil for patient-controlled intravenous labor analgesia as an alternative to patient-controlled epidural labor analgesia. The results show that remifentanil provides rapid onset of labor analgesia and has comparable outcomes to epidural analgesia in terms of labor progress, forceps delivery, cesarean section rate, and neonatal condition.
GINEKOLOGIA POLSKA
(2023)
Article
Biochemistry & Molecular Biology
Hsin- Tsai, Yu-Chieh Lu, Chih-Wen Zheng, Ming-Chin Yu, An-Hsun Chou, Cheng-Han Lee, Hao-Wei Kou, Jr-Rung Lin, Yu-Hua Lai, Li-Ling Chang, Chao-Wei Lee
Summary: Adequate pain control is crucial following abdominal surgeries. This study compared different analgesia regimens for liver resections and found that patient-controlled thoracic epidural analgesia (TEA) required the least amount of opioid. However, intravenous patient-controlled analgesia with bilateral rectus sheath and subcostal transversus abdominis plane nerve blocks (IV-PCA + NBs) showed comparable postoperative outcomes in terms of time to remove nasogastric tube/urinary catheter, start the diet, and length of hospital stay.
Article
Clinical Neurology
Le Xu, Pei Zhang, Wei Long, Rurong Wang, Xuehan Li
Summary: This study compared the efficacy of patient-controlled caudal epidural analgesia (PCCA) and patient-controlled intravenous analgesia (PCIA) after perianal surgery, finding that the PCCA group had better analgesic effect compared to the PCIA group, with no significant differences in PCA usage and catheterization rates between the two groups.
Article
Anesthesiology
Wenwen Xu, Youpei Li, Nanqi Li, Yu Sun, Chao Wang, Ke An
Summary: This study suggests that combining thoracic epidural analgesia (TEA) with patient controlled intravenous analgesia (PCIA) can improve postoperative pain control and promote early recovery for patients undergoing laparotomy, without increasing adverse effects and overall cost of hospitalization.
BMC ANESTHESIOLOGY
(2022)
Article
Integrative & Complementary Medicine
Huang Min-li, Fang Chang-ping, Zhao Hai-yan, Zhang Zi-jing, Wu Shu-zhen, Yi Wei, Li Shang-rong, Wu Ling-ling
Summary: The study demonstrated that acupoint injection combined with CSEA plus PCEA for labor analgesia can reduce anesthetic consumption, improve analgesic quality, and decrease adverse reactions in parturients.
CHINESE JOURNAL OF INTEGRATIVE MEDICINE
(2022)
Article
Oncology
Yuya Murata, Kumiko Yamada, Yuto Hamaguchi, Tomohiro Ohigashi, Kazushi Maruo, Soichiro Yamashita, Makoto Tanaka
Summary: In the interstitial brachytherapy for gynecologic malignancies, patient-controlled epidural analgesia (PCEA) and patient-controlled intravenous analgesia (PCIA) were more effective than conventional intravenous opioids for pain management. However, adverse events associated with PCEA and PCIA did not decrease.
Article
Obstetrics & Gynecology
Peijun Zhang, Zhiqiang Yu, Meili Zhai, Jian Cui, Jianbo Wang
Summary: Remifentanil patient-controlled analgesia (rPCA) and epidural analgesia (EA) showed similar satisfaction levels for pain relief during labor, but rPCA was associated with higher pain intensity and increased risk of maternal oxygen desaturation. Further studies are needed to provide more evidence for the routine use of rPCA during labor.
GYNECOLOGIC AND OBSTETRIC INVESTIGATION
(2021)
Article
Clinical Neurology
Emmanuel A. Adeyemo, Salah G. Aoun, Umaru Barrie, Madelina L. Nguyen, Zachary D. Johnson, Kristen Hall, Valery Peinado Reyes, Tarek Y. El Ahmadieh, Owoicho Adogwa, David L. McDonagh, Carlos A. Bagley
Summary: This study aimed to investigate the impact of epidural analgesia on pain control and outcomes after adult degenerative scoliosis surgery, showing that epidural analgesia can provide optimal pain control and promote greater early ambulation in patients.
Article
Anesthesiology
Wiebke Falk, Anders Magnuson, Christina Eintrei, Ragnar Henningsson, Par Myrelid, Peter Matthiessen, Anil Gupta
Summary: This study found no significant difference in disease-free survival at 5 years between patients undergoing colorectal cancer surgery with thoracic epidural analgesia (TEA) versus patient-controlled intravenous analgesia (PCA) with morphine. While TEA provided better pain relief during the first 24 hours postoperatively, there were no other differences in outcomes compared to PCA.
BRITISH JOURNAL OF ANAESTHESIA
(2021)
Article
Surgery
Gen Ebara, Shinichi Sakuramoto, Kazuaki Matsui, Keiji Nishibeppu, Shouhei Fujita, Shiro Fujihata, Shuichiro Oya, Seigi Lee, Yutaka Miyawaki, Hirofumi Sugita, Hiroshi Sato, Keishi Yamashita
Summary: This study compared the efficacy of patient-controlled intravenous analgesia with regular acetaminophen (PCIA + Ace) and patient-controlled thoracic epidural analgesia (PCEA) for postoperative pain control in laparoscopic gastrectomy. The results showed that patients in the PCIA + Ace group had significantly better pain scores during coughing or movement compared to those in the PCEA group. Additionally, the PCIA + Ace group had a lower frequency of additional rescue analgesic use and a higher rate of reduction or interruption of the patient-controlled analgesic dose.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Medicine, General & Internal
Chun-Yu Chang, Yu-Kang Tu, Ming-Chang Kao, Ping-Cheng Shih, I-Min Su, Han-Yu Lin, Yung-Jiun Chien, Meng-Yu Wu, Chih-Hao Chen, Chu-Ting Chen
Summary: This study aimed to evaluate the analgesic and adverse effects of opioids administered via IVPCA or PCEA in parturients who have undergone caesarean section. The findings showed that PCEA fentanyl had better analgesic effects and lower odds of developing nausea/vomiting and sedation/drowsiness compared to IVPCA morphine. However, PCEA fentanyl may be more likely to cause pruritus.
Article
Medicine, General & Internal
Ru-Ying Pang, Yao-Hua Shen, Xiao-Qin Jin, Hai-Feng Xu, Yang Wang, Bin-Xiang Zhu, Su-Feng Lin, Fei Xiao
Summary: This study evaluated the efficacy of combining different doses of dexmedetomidine or fentanyl with ropivacaine for labor analgesia. The results showed that dexmedetomidine (0.3 and 0.4 μg/ml) reduced the amount of ropivacaine administered and minimized opioid-related side effects. This study provided evidence for the potential of dexmedetomidine as an alternative to opioids for labor analgesia, and further research is needed to confirm its benefits.
FRONTIERS IN MEDICINE
(2022)
Article
Surgery
Takamichi Igarashi, Norifumi Harimoto, Yusuke Matsui, Ryo Muranushi, Takahiro Yamanaka, Kei Hagiwara, Kouki Hoshino, Norihiro Ishii, Mariko Tsukagoshi, Akira Watanabe, Norio Kubo, Kenichiro Araki, Shigeru Saito, Ken Shirabe
Summary: This study found that male sex and longer operation time were significant risk factors for postoperative pancreatic fistula after distal pancreatectomy. A thick pancreas was more likely to cause clinical pancreatic fistula. Intraoperative and postoperative analgesia methods were not significantly associated with clinical pancreatic fistula.
Article
Anesthesiology
E. Roofthooft, N. Filetici, M. Van Houwe, P. Van Houwe, A. Barbe, S. Fieuws, S. Rex, C. A. Wong, M. Van de Velde
Summary: The aim of neuraxial analgesia is to achieve excellent pain relief with the fewest adverse effects. The programmed intermittent epidural bolus technique has been introduced as a maintenance technique for epidural analgesia. Compared to patient-controlled epidural analgesia without background infusion, programmed intermittent epidural bolus is associated with less breakthrough pain, lower pain scores, higher local anaesthetic consumption, and comparable motor block.
Letter
Anesthesiology
Jozef Klucka, Martina Kosinova, Petr Stourac, Milan Kratochvil
EUROPEAN JOURNAL OF ANAESTHESIOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Bretislav Lipovy, Martin Hladik, Petr Stourac, Serhiy Forostyak
Summary: The case report highlights the use of lyophilized amniotic membrane in accelerating wound healing in a patient with TEN, showing significant results in the facial area. The application of amniotic membrane did not result in side effects or infections, demonstrating excellent biocompatibility and accelerated re-epithelialization.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Pediatrics
Milan Urik, Michal Bartos, Sona Sikolova, Jana Jancikova, Klara Perceova, Jiri Jarkovsky, Eva Klabusayova, Petr Stourac, Petr Jabandziev
Summary: Increased blood pressure and longer surgery time were identified as risk factors for postoperative bleeding after adenoidectomy in children in this prospective study, providing new information to complement current knowledge in the field.
Article
Obstetrics & Gynecology
Ines Nunes, Corinne Dupont, Susanna Timonen, Diogo Ayres de Campos, Vanessa Cole, Christiane Schwarz, Anneke Kwee, Branka Yli, Christophe Vayssiere, Georges-Emmanuel Roth, Elko Gliozheni, Yuliya Savochkina, Marina Ivanisevic, Petr Janku, Susanna Timonen, George Daskalakis, Artur Beke, Susana Santo, Mirjam Druskovic, J. J. Duvekot, Alex Farr, Michel Dreyfus
Summary: The use of oxytocin for labor induction and augmentation should be carefully considered in appropriate conditions with continuous cardiotocography monitoring and administration of standard doses through intravenous infusion. Regular auditing of oxytocin use is recommended for quality assurance.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2022)
Article
Environmental Sciences
Jiri Palat, Petr Kukucka, Garry P. Codling, Elliott J. Price, Petr Janku, Jana Klanova
Summary: A 96-well plate solid phase extraction method was developed for determination of selected POPs in low volume blood serum, with extraction efficiency tested on certified reference materials and demonstrated on real samples from pregnant women.
Article
Environmental Sciences
Abanoub Riad, Anna Jouzova, Batuhan Ustun, Eliska Lagova, Lukas Hruban, Petr Janku, Andrea Pokorna, Jitka Klugarova, Michal Koscik, Miloslav Klugar
Summary: The study revealed that pregnant and lactating women have a high level of COVID-19 vaccine acceptance, but they tend to prefer delaying their vaccination. Factors such as pregnancy trimester, education level, employment status, and previous live births were found to be significant determinants for COVID-19 vaccine acceptance among this population subset.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Microbiology
Anne-Christine Aust, Eliska Benesova, Veronika Vidova, Katerina Coufalikova, Sona Smetanova, Ivo Borek, Petr Janku, Eva Budinska, Jana Klanova, Vojtech Thon, Zdenek Spacil
Summary: National screening programs use dried blood samples to detect metabolic disorders or aberrant protein functions that may not be clinically evident in newborns, with a focus on gut microbiota metabolites and immunological acute-phase proteins. The delivery method (vaginal or cesarean section) plays a significant role in shaping microbial colonization and influencing the immune system's response and mucosal homeostasis in neonates. The study identified microbial xenobiotic receptors ligands in neonatal blood samples on the second day of life, indicating the potential importance of the human gut microbiota in maintaining immune system homeostasis.
FRONTIERS IN MICROBIOLOGY
(2021)
Review
Pediatrics
Jozef Klucka, Eva Klabusayova, Milan Kratochvil, Tereza Musilova, Vaclav Vafek, Tamara Skrisovska, Martina Kosinova, Pavla Havrankova, Petr Stourac
Summary: In December 2019, SARS-CoV-2 initiated a global COVID-19 pandemic, which still continues in 2022. COVID-19 has had a significant impact on pediatric intensive care, with the emergence of multisystemic inflammatory syndrome in children. Despite the availability of vaccines for all age groups, COVID-19 remains a major clinical challenge in adult and pediatric intensive care in 2022, due to new viral mutations and variable vaccination rates.
Letter
Anesthesiology
Martina Klincova, Dagmar Stepankova, Ivana Schroderova, Eva Klabusayova, Edita Ostadalova, Iveta Valaskova, Lenka Fajkusova, Jana Zidkova, Renata Gaillyova, Petr Stourac
BRITISH JOURNAL OF ANAESTHESIA
(2022)
Review
Pediatrics
Milan Kratochvil, Jozef Klucka, Eva Klabusayova, Tereza Musilova, Vaclav Vafek, Tamara Skrisovska, Jana Djakow, Pavla Havrankova, Denisa Osinova, Petr Stourac
Summary: Nutrition support is crucial in the treatment of critically ill children in pediatric intensive care. Due to their smaller energy reserves and higher metabolic demands, children are more vulnerable to malnutrition. Oral or enteral nutrition via a gastric tube is preferred, unless contraindicated. High protein delivery is emphasized during the acute phase, and high energy demands are key for positive outcomes during the anabolic phase and intensive rehabilitation.
Review
Pediatrics
Eva Klabusayova, Jozef Klucka, Milan Kratochvil, Tereza Musilova, Vaclav Vafek, Tamara Skrisovska, Jana Djakow, Martina Kosinova, Pavla Havrankova, Petr Stourac
Summary: Traditionally, uncuffed tubes were used to reduce the risk of postextubation stridor in pediatric patients, but they failed to reduce the risk of subglottic swelling. Currently, properly used cuffed tubes are recommended in emergency, anesthesiology, and intensive care settings. However, there is variability in clinical practice, particularly in the intensive care area.
Article
Obstetrics & Gynecology
Samuel Tvarozek, Martin Huser, Martina Dostalova, Martina Szypulova, Ivan Horvath
Summary: The use of transvaginal mesh repair for pelvic organ prolapse can improve women's sexual function.
JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2022)
Article
Pediatrics
Martina Kosinova, Petr Stourac, Tereza Prokopova, Tereza Vafkova, Vaclav Vafek, Daniel Barvik, Tamara Skrisovska, Jan Dvoracek, Jana Djakow, Jozef Klucka, Jiri Jarkovsky, Pavel Plevka
Summary: This study assessed the efficacy of mouth-to-mouth breathing through a breathable respirator during Basic Life Support (BLS) training. The results showed that mouth-to-mouth ventilation through the respirator had an effectivity greater than 90%.
Letter
Anesthesiology
Michaela Richtrova, Olga Koskova, Petr Marcian, Marek Joukal, Tereza Musilova, Martin Janku, Dominik Fabian, Dominika Matyskova, Petr Stourac
BRITISH JOURNAL OF ANAESTHESIA
(2023)
Article
Anesthesiology
I Krikava, V. Kubricht, J. Lejcko, J. Malek, P. Sevcik, P. Stourac, M. Kosinova, J. Kozak
ANESTEZIOLOGIE A INTENZIVNI MEDICINA
(2022)