The polarity protein Inturned links NPHP4 to Daam1 to control the subapical actin network in multiciliated cells

The Rac1 regulator ELMO controls basal body migration and docking in multiciliated cells through interaction with Ezrin

(2015) D. Epting et al.   DEVELOPMENT

The Drosophila planar polarity gene multiple wing hairs directly regulates the actin cytoskeleton

(2015) Q. Lu et al.   DEVELOPMENT

Multiciliated Cells

(2014) Eric R. Brooks et al.   CURRENT BIOLOGY

The proteins encoded by the Drosophila Planar Polarity Effector genes inturned, fuzzy and fritz interact physically and can re-pattern the accumulation of “upstream” Planar Cell Polarity proteins

(2014) Ying Wang et al.   DEVELOPMENTAL BIOLOGY

Making the Connection: Ciliary Adhesion Complexes Anchor Basal Bodies to the Actin Cytoskeleton

(2014) Ioanna Antoniades et al.   DEVELOPMENTAL CELL

The nphp-2 and arl-13 Genetic Modules Interact to Regulate Ciliogenesis and Ciliary Microtubule Patterning in C. elegans

(2014) Simon R. F. Warburton-Pitt et al.   PLoS Genetics

NPHP4mutation is linked to cerebello-oculo-renal syndrome and male infertility

(2013) A.M. Alazami et al.   CLINICAL GENETICS

The roles of evolutionarily conserved functional modules in cilia-related trafficking

(2013) Ching-Hwa Sung et al.   NATURE CELL BIOLOGY

ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3

(2013) Sylvia Hoff et al.   NATURE GENETICS

Planar Cell Polarity Links Axes of Spatial Dynamics in Neural-Tube Closure

(2012) Tamako Nishimura et al.   CELL

Clinical spectrum and pathogenesis of nephronophthisis

(2012) Thomas Benzing et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

The base of the cilium: roles for transition fibres and the transition zone in ciliary formation, maintenance and compartmentalization

(2012) Jeremy F Reiter et al.   EMBO REPORTS

Mapping the NPHP-JBTS-MKS Protein Network Reveals Ciliopathy Disease Genes and Pathways

(2011) Liyun Sang et al.   CELL

PCP effector proteins inturned and fuzzy play nonredundant roles in the patterning but not convergent extension of mammalian neural tube

(2011) Westley Heydeck et al.   DEVELOPMENTAL DYNAMICS

Nephrocystin-4 is required for pronephric duct-dependent cloaca formation in zebrafish

(2011) Krasimir Slanchev et al.   HUMAN MOLECULAR GENETICS

Control of the Wnt pathways by nephrocystin-4 is required for morphogenesis of the zebrafish pronephros

(2011) Céline Burcklé et al.   HUMAN MOLECULAR GENETICS

Nephrocystin-4 Regulates Pyk2-induced Tyrosine Phosphorylation of Nephrocystin-1 to Control Targeting to Monocilia

(2011) Max C. Liebau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MKS and NPHP modules cooperate to establish basal body/transition zone membrane associations and ciliary gate function during ciliogenesis

(2011) Corey L. Williams et al.   JOURNAL OF CELL BIOLOGY

Actin and microtubules drive differential aspects of planar cell polarity in multiciliated cells

(2011) Michael E. Werner et al.   JOURNAL OF CELL BIOLOGY

Planar cell polarity signaling, cilia and polarized ciliary beating

(2010) John B Wallingford   CURRENT OPINION IN CELL BIOLOGY

MIM and Cortactin Antagonism Regulates Ciliogenesis and Hedgehog Signaling

(2010) Marina Bershteyn et al.   DEVELOPMENTAL CELL

The Drosophila Planar Polarity Proteins Inturned and Multiple Wing Hairs Interact Physically and Function Together

(2010) Q. Lu et al.   GENETICS

Normal Ciliogenesis Requires Synergy between the Cystic Kidney Disease Genes MKS-3 and NPHP-4

(2010) C. L. Williams et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

A nucleator arms race: cellular control of actin assembly

(2010) Kenneth G. Campellone et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Inversin relays Frizzled-8 signals to promote proximal pronephros development

(2010) S. Lienkamp et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton

(2009) H. R. Dawe et al.   JOURNAL OF CELL SCIENCE

Unleashing formins to remodel the actin and microtubule cytoskeletons

(2009) Melissa A. Chesarone et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Regulation of ciliary polarity by the APC/C

(2009) A. Ganner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New players in actin polymerization – WH2-domain-containing actin nucleators

(2009) Britta Qualmann et al.   TRENDS IN CELL BIOLOGY

Loss of Nephrocystin-3 Function Can Cause Embryonic Lethality, Meckel-Gruber-like Syndrome, Situs Inversus, and Renal-Hepatic-Pancreatic Dysplasia

(2008) Carsten Bergmann et al.   AMERICAN JOURNAL OF HUMAN GENETICS

TheCaenorhabditis elegansnephrocystins act as global modifiers of cilium structure

(2008) Andrew R. Jauregui et al.   JOURNAL OF CELL BIOLOGY

Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells

(2008) Tae Joo Park et al.   NATURE GENETICS

Lifeact: a versatile marker to visualize F-actin

(2008) Julia Riedl et al.   NATURE METHODS