PC7 and the related proteases Furin and Pace4 regulate E-cadherin function during blastocyst formation

Opposite Roles of Furin and PC5A in N-Cadherin Processing

(2015) Deborah Maret et al.   NEOPLASIA

Initiation of Hippo signaling is linked to polarity rather than to cell position in the pre-implantation mouse embryo

(2014) Shihadeh Anani et al.   DEVELOPMENT

Gata6, Nanog and Erk signaling control cell fate in the inner cell mass through a tristable regulatory network

(2014) S. Bessonnard et al.   DEVELOPMENT

Limited predictive value of blastomere angle of division in trophectoderm and inner cell mass specification

(2014) T. Watanabe et al.   DEVELOPMENT

Notch and Hippo Converge on Cdx2 to Specify the Trophectoderm Lineage in the Mouse Blastocyst

(2014) Teresa Rayon et al.   DEVELOPMENTAL CELL

The Hippo Pathway Member Nf2 Is Required for Inner Cell Mass Specification

(2013) Katie Cockburn et al.   CURRENT BIOLOGY

Polarity-Dependent Distribution of Angiomotin Localizes Hippo Signaling in Preimplantation Embryos

(2013) Yoshikazu Hirate et al.   CURRENT BIOLOGY

Cadherin-dependent filopodia control preimplantation embryo compaction

(2013) Juan Carlos Fierro-González et al.   NATURE CELL BIOLOGY

Angiomotin prevents pluripotent lineage differentiation in mouse embryos via Hippo pathway-dependent and -independent mechanisms

(2013) Chuen Yan Leung et al.   Nature Communications

Single-Cell Profiling of Epigenetic Modifiers Identifies PRDM14 as an Inducer of Cell Fate in the Mammalian Embryo

(2013) Adam Burton et al.   Cell Reports

Multiple post-translational modifications regulate E-cadherin transport during apoptosis

(2012) F. Geng et al.   JOURNAL OF CELL SCIENCE

The biology and therapeutic targeting of the proprotein convertases

(2012) Nabil G. Seidah et al.   NATURE REVIEWS DRUG DISCOVERY

A Homolog of Subtilisin-Like Proprotein Convertase 7 Is Essential to Anterior Neural Development in Xenopus

(2012) Sema Senturker et al.   PLoS One

Thinking outside the cell: how cadherins drive adhesion

(2012) Julia Brasch et al.   TRENDS IN CELL BIOLOGY

Intercellular Interactions, Position, and Polarity in Establishing Blastocyst Cell Lineages and Embryonic Axes

(2012) R. O. Stephenson et al.   Cold Spring Harbor Perspectives in Biology

Lineage mapping the pre-implantation mouse embryo by two-photon microscopy, new insights into the segregation of cell fates

(2011) Katie McDole et al.   DEVELOPMENTAL BIOLOGY

The microenvironment patterns the pluripotent mouse epiblast through paracrine Furin and Pace4 proteolytic activities

(2011) D. Mesnard et al.   GENES & DEVELOPMENT

Oct4 kinetics predict cell lineage patterning in the early mammalian embryo

(2011) Nicolas Plachta et al.   NATURE CELL BIOLOGY

Initiation of trophectoderm lineage specification in mouse embryos is independent of Cdx2

(2010) G. Wu et al.   DEVELOPMENT

FGF signal-dependent segregation of primitive endoderm and epiblast in the mouse blastocyst

(2010) Y. Yamanaka et al.   DEVELOPMENT

Disorganized epithelial polarity and excess trophectoderm cell fate in preimplantation embryos lacking E-cadherin

(2010) R. O. Stephenson et al.   DEVELOPMENT

The Proprotein Convertase PC7

(2010) Estelle Rousselet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Imaging proprotein convertase activities and their regulation in the implanting mouse blastocyst

(2010) Daniel Mesnard et al.   JOURNAL OF CELL BIOLOGY

Recycling endosomes in apical plasma membrane domain formation and epithelial cell polarity

(2010) Magdalena R. Golachowska et al.   TRENDS IN CELL BIOLOGY

The Hippo Signaling Pathway Components Lats and Yap Pattern Tead4 Activity to Distinguish Mouse Trophectoderm from Inner Cell Mass

(2009) Noriyuki Nishioka et al.   DEVELOPMENTAL CELL

Site-specific Cleavage of BMP4 by Furin, PC6, and PC7

(2009) Sylvia M. Nelsen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inactivation of aPKCλ Reveals a Context Dependent Allocation of Cell Lineages in Preimplantation Mouse Embryos

(2009) Nicolas Dard et al.   PLoS One

Formation of the embryonic-abembryonic axis of the mouse blastocyst: relationships between orientation of early cleavage divisions and pattern of symmetric/asymmetric divisions

(2008) M. Bischoff et al.   DEVELOPMENT

Selective inhibition of proprotein convertases represses the metastatic potential of human colorectal tumor cells

(2008) Nathalie Scamuffa et al.   JOURNAL OF CLINICAL INVESTIGATION

Tight junction biogenesis during early development

(2007) Judith J. Eckert et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Cdx2 acts downstream of cell polarization to cell-autonomously promote trophectoderm fate in the early mouse embryo

(2007) Amy Ralston et al.   DEVELOPMENTAL BIOLOGY

Tead4 is required for specification of trophectoderm in pre-implantation mouse embryos

(2007) Noriyuki Nishioka et al.   MECHANISMS OF DEVELOPMENT