Simultaneous quantitative analyses of indole and oxindole alkaloids of Uncaria Hook in rat plasma and brain after oral administration of the traditional Japanese medicine Yokukansan using high-performance liquid chromatography with tandem mass spectrometr

Geissoschizine methyl ether, an alkaloid in Uncaria hook, is a potent serotonin1A receptor agonist and candidate for amelioration of aggressiveness and sociality by yokukansan

(2012) A. Nishi et al.   NEUROSCIENCE

The Blood–Brain Barrier Permeability of Geissoschizine Methyl Ether in Uncaria Hook, a Galenical Constituent of the Traditional Japanese Medicine Yokukansan

(2011) Sachiko Imamura et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Yokukansan, a traditional Japanese medicine, ameliorates memory disturbance and abnormal social interaction with anti-aggregation effect of cerebral amyloid β proteins in amyloid precursor protein transgenic mice

(2011) H. Fujiwara et al.   NEUROSCIENCE

Metabolism and Pharmacokinetics of Rhynchophylline in Rats

(2010) Wei Wang et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Yokukansan, a kampo medicine, protects against glutamate cytotoxicity due to oxidative stress in PC12 cells

(2010) Zenji Kawakami et al.   JOURNAL OF ETHNOPHARMACOLOGY

Effect of yokukansan, a traditional Japanese medicine, on social and aggressive behaviour ofpara-chloroamphetamine-injected rats

(2010) Hitomi Kanno et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Effects of Yokukansan, a Traditional Japanese Medicine, on Memory Disturbance and Behavioral and Psychological Symptoms of Dementia in Thiamine-Deficient Rats

(2009) Yasushi Ikarashi et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Partial agonistic effect of yokukansan on human recombinant serotonin 1A receptors expressed in the membranes of Chinese hamster ovary cells

(2009) Kiyoshi Terawaki et al.   JOURNAL OF ETHNOPHARMACOLOGY

Neuroprotective effects of yokukansan, a traditional japanese medicine, on glutamate-mediated excitotoxicity in cultured cells

(2009) Z. Kawakami et al.   NEUROSCIENCE

Effects of yokukansan, a traditional Japanese medicine, on aggressiveness induced by intracerebroventricular injection of amyloidβprotein into mice

(2009) Kyoji Sekiguchi et al.   PHYTOTHERAPY RESEARCH

A randomized cross-over study of a traditional Japanese medicine (kampo), yokukansan, in the treatment of the behavioural and psychological symptoms of dementia

(2008) Katsuyoshi Mizukami et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Ameliorative effects of yokukansan, a traditional Japanese medicine, on learning and non-cognitive disturbances in the Tg2576 mouse model of Alzheimer's disease

(2008) Masahiro Tabuchi et al.   JOURNAL OF ETHNOPHARMACOLOGY

Neuroprotective effects of Yi-Gan San against beta amyloid-induced cytotoxicity on rat cortical neurons

(2008) Masaru Tateno et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Effect of yokukansan on the behavioral and psychological symptoms of dementia in elderly patients with Alzheimer's disease

(2008) Akira Monji et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY