Enhancement by Glycyrrhizae Radix of hepatic metabolism of hypaconitine, a major bioactive and toxic component of Aconiti Laterlis Radix, evaluated by HPLC-TQ-MS/MS analysis

Development and Validation of a High-Performance Liquid Chromatography—Tandem Mass Spectrometry Method for the Rapid Simultaneous Quantification of Aconitine, Mesaconitine, and Hypaconitine in Rat Plasma after Oral Administration of Sini Decoction

(2013) Lei-ping He et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Microsomal cytochrome P450-mediated metabolism of hypaconitine, an active and highly toxic constituent derived from Aconitum species

(2011) Ling Ye et al.   TOXICOLOGY LETTERS

Determination of aconitine, hypaconitine and mesaconitine in urine using hollow fiber liquid-phase microextraction combined with high-performance liquid chromatography

(2010) Yang Yang et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Contrasting Influence of NADPH and a NADPH-Regenerating System on the Metabolism of Carbonyl-Containing Compounds in Hepatic Microsomes

(2009) C. S. Mazur et al.   DRUG METABOLISM AND DISPOSITION

Toxicity Assessment of Nine Types of Decoction Pieces from the Daughter Root ofAconitum carmichaeli(Fuzi) Based on the Chemical Analysis of their Diester Diterpenoid Alkaloids

(2009) Guanghua Lu et al.   PLANTA MEDICA

Simultaneous quantitation of aconitine, mesaconitine, hypaconitine, benzoylaconine, benzoylmesaconine and benzoylhypaconine in human plasma by liquid chromatography–tandem mass spectrometry and pharmacokinetics evaluation of “SHEN-FU” injectable powder

(2008) Fan Zhang et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES