Article
Ophthalmology
Siddharth Nath, Carl Shen, Alex Koziarz, Laura Banfield, Behnam Nowrouzi-Kia, Mark A. Fava, William G. Hodge
Summary: Transepithelial and epithelium-off corneal cross-linking show significant differences in corneal ectasia treatment, with the latter being more effective but less safe in comparison.
Article
Ophthalmology
Rebecca Stein, Stephan Ong Tone, Gerald Lebovic, Neera Singal, Wendy Hatch
Summary: This study evaluates the relationship between subjective (slit lamp examination [SLE]) and objective (densitometry) measurements of corneal haze after accelerated corneal crosslinking (aCXL). It also assesses the relationship between densitometry and corrected distance visual acuity (CDVA) and determines the effect of baseline characteristics on densitometry after aCXL. The study findings show a significant association between subjective haze with SLE and densitometry, and increased densitometry after aCXL is associated with a reduction in CDVA. Age and preoperative maximum keratometry (K-max) are significant predictors of densitometry.
ACTA OPHTHALMOLOGICA
(2023)
Article
Ophthalmology
Prema Padmanabhan, Bernardo T. Lopes, Ashkan Eliasy, Ahmed Abass, Riccardo Vinciguerra, Paolo Vinciguerra, Renato Ambrosio, Ahmed Elsheikh
Summary: This study evaluated the corneal material properties in healthy individuals and keratoconic patients using the stress-strain index (SSI). The results showed significant differences in SSI between different groups, with a progressive reduction in SSI as the disease progressed. Furthermore, SSI was positively correlated with age.
JOURNAL OF CATARACT AND REFRACTIVE SURGERY
(2022)
Review
Ophthalmology
Hamza Pasha, Laura Palazzolo, Gaurav Prakash, Vishal Jhanji
Summary: Recent research on corneal collagen crosslinking (CXL) has focused on modifying treatment protocols to maximize corneal stability and shorten procedure time. Accelerated protocols have shown success but concerns remain about long-term corneal stability. Pulsed protocols may enhance the long-term efficacy of accelerated designs.
CURRENT OPINION IN OPHTHALMOLOGY
(2021)
Review
Medicine, General & Internal
Louise Pellegrino Gomes Esporcatte, Marcella Q. Q. Salomao, Alexandre Batista da Costa Neto, Aydano P. Machado, Bernardo T. Lopes, Renato Ambrosio Jr
Summary: Different diagnostic strategies are needed for patients with ectatic corneal diseases (ECDs), including screening, confirmation of diagnosis, classification, severity staging, prognostic assessment, and clinical follow-up. These strategies enable personalized treatments and are crucial for identifying high-risk patients and improving diagnostics.
Article
Ophthalmology
Clementine David, Dan Z. Reinstein, Timothy J. Archer, Sofiene Kallel, Ryan S. Vida, Isabelle Goemaere, Roxane Cuyaubere, Marie Borderie, Laurent Laroche, Vincent Borderie, Nacim Bouheraoua
Summary: After ICRS implantation, significant epithelial thickening occurs, especially near the implanted ICRS, to compensate for the thickening of the epithelium over the cone due to regularization of the stromal surface.
JOURNAL OF REFRACTIVE SURGERY
(2021)
Review
Dermatology
Jean-Michel Amici, Olivier Cogrel, Marie Jourdan, Catherine Raimbault, Ludivine Canchy, Delphine Kerob, Diane C. C. Madfes, Yan Tian, Elena Araviiskaia
Summary: A comprehensive understanding of non-surgical and surgical procedures is crucial for minimizing complications and maximizing the benefits for patients. Individuals with darker skin and high Fitzpatrick phototype are more susceptible to pigmentation disorders, which may be treated or arise as a complication of aesthetic procedures. A group of experts in cosmetic surgery and dermatology reviewed literature and provided practical recommendations for optimizing outcomes and supporting skincare before, during, and after procedures. Broad-spectrum sunscreen, supportive skincare, and adjunctive skincare with healing and anti-inflammatory properties are key in preventing and improving pigmentation disorders.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2023)
Article
Medicine, General & Internal
Cosimo Mazzotta, Anna Pandolfi, Marco Ferrise
Summary: This study aims to assess the preliminary clinical results of a new method called Epi-On ACXL in the treatment of progressive keratoconus. The results show that this treatment can improve visual acuity and stabilize the progression of the disease.
FRONTIERS IN MEDICINE
(2023)
Article
Gastroenterology & Hepatology
Miguel F. F. Cunha, Gianluca Pellino
Summary: There is a bidirectional relationship between climate change and health care, as health care contributes to climate change and climate change threatens public health. However, the environmental costs associated with health care are often overlooked and there is a lack of global awareness and guidance on sustainable surgical practices.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY
(2023)
Article
Ophthalmology
Steven A. Greenstein, Austin S. Yu, John D. Gelles, Hamoon Eshraghi, Peter S. Hersh
Summary: CTAK is a promising procedure to improve visual acuity and topography in patients with KC and ectasia.
JOURNAL OF CATARACT AND REFRACTIVE SURGERY
(2023)
Article
Multidisciplinary Sciences
Xueqing Lu, Yimeng Fan, Zhao Liu, Xuanyu Qiu, Qiang Shi, Ning Gao, Shengjian Mi, Cheng Pei
Summary: This study compared the accuracy of central CST reduction in SMILE and FS-LASIK. The results showed that the central CST reduction was overestimated in the SMILE group and underestimated in the FS-LASIK group. The planned-achieved difference of central CST reduction was positively correlated with preoperative MRSE and planned central CST reduction in both groups. Estimation using MR without nomogram adjustment may be feasible for SMILE and FS-LASIK in clinical practice.
SCIENTIFIC REPORTS
(2023)
Article
Ophthalmology
Steven A. Greenstein, Austin S. Yu, John D. Gelles, Steven Huang, Peter S. Hersh
Summary: This study reports on the topographic and visual outcomes 10 years after corneal cross-linking in patients with progressive keratoconus and corneal ectasia after refractive surgery. The results showed that visual acuity and corneal topography remained stable in the entire cohort 10 years after cross-linking, with eyes with keratoconus being more stable than those with corneal ectasia in the long-term.
EYE & CONTACT LENS-SCIENCE AND CLINICAL PRACTICE
(2023)
Article
Biotechnology & Applied Microbiology
Yiyong Xian, Yu Zhao, Ling Sun, Xiaoyu Zhang, Lan Ding, Zesheng Liu, Yuan Li, Yanlan Ding, Lin Jiang, Xingtao Zhou, Yang Shen
Summary: This study compared the differences in corneal biomechanics between keratoconus and normal eyes. It found that corneal biomechanical parameters differed between eyes with forme fruste keratoconus and normal eyes. Additionally, in the keratoconus group, bilateral differences in corneal biomechanical parameters were significantly increased, which may aid in the early detection of keratoconus.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Multidisciplinary Sciences
Mohamed Ghaly, Diana Jaber, Mario Matthaei, Claus Cursiefen, Alexander Haendel, Juliane Koeberlein-Neu, Robert Hoerster, Sebastian Siebelmann
Summary: The analysis of internet search queries can provide valuable insights into the public interest and medical need for corneal, cataract, and refractive surgery. This study finds a significant correlation between internet search queries and actual healthcare system data, suggesting that it could be used for forecasting and now-casting surgical procedures.
SCIENTIFIC REPORTS
(2022)
Article
Ophthalmology
Maria Miura, Pia Leon, Yoav Nahum, Myriam S. Boehm, Michael Mimouni, Michael W. Belin, Lynette Johns, Joseph B. Ciolino
Summary: The purpose of this study was to assess the changes in Scheimpflug imaging after penetrating keratoplasty (PK) in keratoconus (KC) patients over a 5-year period. The study included 31 eyes of 31 patients who underwent their first PK. The results showed a significant increase in maximal keratometry (Kmax) at 3 and 5 years after PK, as well as changes in anterior and posterior best fit sphere. The study also found a negative correlation between host trephination size and progression of Kmax.
Review
Pharmacology & Pharmacy
Mohammed Ziaei, Carol Greene, Colin R. Green
ADVANCED DRUG DELIVERY REVIEWS
(2018)
Letter
Ophthalmology
Mohammed Ziaei, Akilesh Gokul Boptom, Dipika V. Patel, Charles N. J. McGhee
CANADIAN JOURNAL OF OPHTHALMOLOGY-JOURNAL CANADIEN D OPHTALMOLOGIE
(2018)
Article
Ophthalmology
Sophie X. Deng, Vincent Borderie, Clara C. Chan, Reza Dana, Francisco C. Figueiredo, Jose A. P. Gomes, Graziella Pellegrini, Shigeto Shimmura, Friedrich E. Kruse, Claus Cursiefen, Sheraz Daya, Ali Djalilian, Beatrice Frueh, Jesper Hjortdal, Edward Holland, Stephen Kaufman, Shigeru Kinoshita, Barry Lee, Mark Mannis, Jesus Merayo, Victor Perez, Paolo Rama, Virender Sangwan, Alex Shortt, Allan Slomovic, Avi Solomon, Donald Tan, Ray Tsai, Scheffer Tseng, Elmer Tu, Qihua Le, Tatiana C. G. Jimena, Virginia Sceberras, Eustachio Attico
Article
Ophthalmology
Sheraz M. Daya, Soon-Phaik Chee, Seng-Ei Ti, Richard Packard, David H. Mordaunt
JOURNAL OF CATARACT AND REFRACTIVE SURGERY
(2019)
Article
Ophthalmology
Sheraz Daya, Soon-Phaik Chee, Seng-Ei Ti, Richard Packard, David H. Mordaunt
BRITISH JOURNAL OF OPHTHALMOLOGY
(2020)
Article
Ophthalmology
We Fong Siah, Kostas Boboridis, Petrina Tan, Andre S. Litwin, Sheraz M. Daya, Raman Malhotra
ACTA OPHTHALMOLOGICA
(2019)
Article
Ophthalmology
Mohammed Ziaei, Akilesh Gokul, Hans Vellara, Jay Meyer, Dipika Patel, Charles N. J. McGhee
CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2019)
Article
Ophthalmology
Mohammed Ziaei, Hans Vellara, Akilesh Gokul, Dipika Patel, Charles N. J. McGhee
Article
Ophthalmology
Mohammed Ziaei, Hans R. Vellara, Akilesh Gokul, Noor Q. Ali, Charles N. J. McGhee, Dipika Patel
CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2020)
Letter
Ophthalmology
Soobin Namkung, Yi W. Goh, Mohammed Ziaei, Charles N. J. McGhee
CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2019)
Article
Ophthalmology
Jennifer R. Evans, Samantha R. de Silva, Mohammed Ziaei, Varo Kirthi, Martin D. Leyland
BRITISH JOURNAL OF OPHTHALMOLOGY
(2020)
Article
Ophthalmology
Mohammed Ziaei, Akilesh Gokul, Hans Vellara, Dipika Patel, Charles N. J. McGhee
CONTACT LENS & ANTERIOR EYE
(2020)
Article
Ophthalmology
Mohammed Ziaei, Jinny J. Yoon, Hans R. Vellara, Akilesh Gokul, Jay J. Meyer, Sachin S. Thakur, Charles Nj McGhee, Dipika Patel
Summary: This study utilized a dynamic ultra-high-speed Scheimpflug camera equipped with a non-contact tonometer to characterize corneal biomechanical properties in keratoconic corneas following continuous high-intensity, high-irradiance corneal cross-linking. The results showed significant changes in corneal viscous properties, particularly in the energy absorbed area, after the cross-linking procedure.
EUROPEAN JOURNAL OF OPHTHALMOLOGY
(2022)
Review
Ophthalmology
Haitham Al-Mahrouqi, Isabella Mei Yan Cheung, Lize Angelo, Tzu-Ying Yu, Akilesh Gokul, Mohammed Ziaei
Summary: Corneal cross-linking is a technique using riboflavin and ultraviolet-A light to strengthen corneal tissue. It has been effective in treating corneal ectasia and has expanded into other applications such as treating microbial keratitis and correcting refractive error. This review provides an overview of current evidence and future developments in non-ectasia applications of corneal cross-linking.
CLINICAL AND EXPERIMENTAL OPTOMETRY
(2023)
Review
Ophthalmology
Lize Angelo, Akilesh Gokul Boptom, Charles McGhee, Mohammed Ziaei
Summary: Corneal crosslinking (CXL) has emerged as an effective method for treating keratoconus and managing other ocular pathologies. This review summarizes the current role of CXL in keratoconus, its alternative uses, and future developments.
ASIA-PACIFIC JOURNAL OF OPHTHALMOLOGY
(2022)