Mechanotransduction in embryonic vascular development

Signal transduction by vascular endothelial growth factor receptors

(2011) Sina Koch et al.   BIOCHEMICAL JOURNAL

In vivoshear stress response

(2011) Stuart Egginton   BIOCHEMICAL SOCIETY TRANSACTIONS

Heparan sulfate proteoglycan mediates shear stress-induced endothelial gene expression in mouse embryonic stem cell-derived endothelial cells

(2011) Maria Nikmanesh et al.   BIOTECHNOLOGY AND BIOENGINEERING

A blood flow-dependent klf2a-NO signaling cascade is required for stabilization of hematopoietic stem cell programming in zebrafish embryos

(2011) L. Wang et al.   BLOOD

Flow-Dependent Regulation of Krüppel-Like Factor 2 Is Mediated by MicroRNA-92a

(2011) Wei Wu et al.   CIRCULATION

Interaction between alk1 and blood flow in the development of arteriovenous malformations

(2011) P. Corti et al.   DEVELOPMENT

Arterial-venous network formation during brain vascularization involves hemodynamic regulation of chemokine signaling

(2011) J. Bussmann et al.   DEVELOPMENT

Birth Prevalence of Congenital Heart Disease Worldwide

(2011) Denise van der Linde et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Kinematics of cardiac growth: In vivo characterization of growth tensors and strains

(2011) Alkiviadis Tsamis et al.   Journal of the Mechanical Behavior of Biomedical Materials

Dynamic molecular processes mediate cellular mechanotransduction

(2011) Brenton D. Hoffman et al.   NATURE

Tumor Angiogenesis and Vascular Patterning: A Mathematical Model

(2011) Rui D. M. Travasso et al.   PLoS One

MicroRNA-21 targets peroxisome proliferators-activated receptor-  in an autoregulatory loop to modulate flow-induced endothelial inflammation

(2011) J. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantitative Three-Dimensional Analysis of Embryonic Chick Morphogenesis Via Microcomputed Tomography

(2010) Jun Sup Kim et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Role of hemodynamic shear stress in cardiovascular disease

(2010) Emanuele Cecchi et al.   ATHEROSCLEROSIS

Current Status of Fetal Cardiac Intervention

(2010) Doff B. McElhinney et al.   CIRCULATION

Moesin1 and Ve-cadherin are required in endothelial cells during in vivo tubulogenesis

(2010) Y. Wang et al.   DEVELOPMENT

Pulsatile shear and Gja5 modulate arterial identity and remodeling events during flow-driven arteriogenesis

(2010) I. Buschmann et al.   DEVELOPMENT

Emerging complexity of microRNA generation cascades

(2010) H. I. Suzuki et al.   JOURNAL OF BIOCHEMISTRY

Erk5 Activation Elicits a Vasoprotective Endothelial Phenotype via Induction of Krüppel-like Factor 4 (KLF4)

(2010) Nils Ohnesorge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Measuring hemodynamics in the developing heart tube with four-dimensional gated Doppler optical coherence tomography

(2010) Michael W. Jenkins et al.   JOURNAL OF BIOMEDICAL OPTICS

A multiscale model for eccentric and concentric cardiac growth through sarcomerogenesis

(2010) Serdar Göktepe et al.   JOURNAL OF THEORETICAL BIOLOGY

MEK5 is Activated by Shear Stress, Activates ERK5 and Induces KLF4 to Modulate TNF Responses in Human Dermal Microvascular Endothelial Cells

(2010) PAUL R. CLARK et al.   MICROCIRCULATION

MicroRNA-mediated integration of haemodynamics and Vegf signalling during angiogenesis

(2010) Stefania Nicoli et al.   NATURE

Haematopoietic stem cells derive directly from aortic endothelium during development

(2010) Julien Y. Bertrand et al.   NATURE

Role of microRNA-23b in flow-regulation of Rb phosphorylation and endothelial cell growth

(2010) K.-C. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-19a mediates the suppressive effect of laminar flow on cyclin D1 expression in human umbilical vein endothelial cells

(2010) X. Qin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-10a regulation of proinflammatory phenotype in athero-susceptible endothelium in vivo and in vitro

(2010) Y. Fang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRPV4-mediated endothelial Ca2+ influx and vasodilation in response to shear stress

(2009) Suelhem A. Mendoza et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Aortic Arch Morphogenesis and Flow Modeling in the Chick Embryo

(2009) Yajuan Wang et al.   ANNALS OF BIOMEDICAL ENGINEERING

PECAM-1 Is Necessary for Flow-Induced Vascular Remodeling

(2009) Zhongming Chen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Shear Stress Increases Expression of the Arterial Endothelial Marker EphrinB2 in Murine ES Cells via the VEGF-Notch Signaling Pathways

(2009) Tomomi Masumura et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Defining the regulation of KLF4 expression and its downstream transcriptional targets in vascular endothelial cells

(2009) Guadalupe Villarreal et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Finite element study of scaffold architecture design and culture conditions for tissue engineering

(2009) Andy L. Olivares et al.   BIOMATERIALS

Fluid shear stress stimulates phosphorylation-dependent nuclear export of HDAC5 and mediates expression of KLF2 and eNOS

(2009) W. Wang et al.   BLOOD

KLF2-induced actin shear fibers control both alignment to flow and JNK signaling in vascular endothelium

(2009) R. A. Boon et al.   BLOOD

Hematopoietic Stem Cell Development Is Dependent on Blood Flow

(2009) Trista E. North et al.   CELL

Ciliary Polycystin-2 Is a Mechanosensitive Calcium Channel Involved in Nitric Oxide Signaling Cascades

(2009) Wissam A. AbouAlaiwi et al.   CIRCULATION RESEARCH

The Molecular Basis of Vascular Lumen Formation in the Developing Mouse Aorta

(2009) Boris Strilić et al.   DEVELOPMENTAL CELL

Mathematical modeling of the capillary-like pattern generated by adrenomedullin-treated human vascular endothelial cells in vitro

(2009) Diego Guidolin et al.   DEVELOPMENTAL DYNAMICS

Differential gene expression in young and senescent endothelial cells under static and laminar shear stress conditions

(2009) Gyeong In Mun et al.   FREE RADICAL BIOLOGY AND MEDICINE

Role of glycocalyx in flow-induced production of nitric oxide and reactive oxygen species

(2009) Robert Kumagai et al.   FREE RADICAL BIOLOGY AND MEDICINE

A Structural Multi-Mechanism Damage Model for Cerebral Arterial Tissue

(2009) Dalong Li et al.   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

Coupling the Hemodynamic Environment to the Evolution of Cerebral Aneurysms: Computational Framework and Numerical Examples

(2009) Paul N. Watton et al.   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

Effect of cell seeding and mechanical loading on vascularization and tissue formation inside a scaffold: A mechano-biological model using a lattice approach to simulate cell activity

(2009) Sara Checa et al.   JOURNAL OF BIOMECHANICS

Efficient postacquisition synchronization of 4-D nongated cardiac images obtained from optical coherence tomography: application to 4-D reconstruction of the chick embryonic heart

(2009) Aiping Liu et al.   JOURNAL OF BIOMEDICAL OPTICS

Vesnarinone downregulates CXCR4 expression via upregulation of Krüppel-like factor 2 in oral cancer cells

(2009) Daisuke Uchida et al.   Molecular Cancer

Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter

(2009) Michael J. Chen et al.   NATURE

Microarray profiling reveals CXCR4a is downregulated by blood flow in vivo and mediates collateral formation in zebrafish embryos

(2009) Ian M. Packham et al.   PHYSIOLOGICAL GENOMICS

Doppler flow velocity waveforms in the embryonic chicken heart at developmental stages corresponding to 5-8 weeks of human gestation

(2009) A. M. Oosterbaan et al.   ULTRASOUND IN OBSTETRICS & GYNECOLOGY

Reversing Blood Flows Act through klf2a to Ensure Normal Valvulogenesis in the Developing Heart

(2009) Julien Vermot et al.   PLOS BIOLOGY

Mechanisms of arteriogenesis

(2008) Weijun Cai et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

KLF2 Primes the Antioxidant Transcription Factor Nrf2 for Activation in Endothelial Cells

(2008) Joost O. Fledderus et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Neural guidance molecules, tip cells, and mechanical factors in vascular development

(2008) F. le Noble et al.   CARDIOVASCULAR RESEARCH

Role of cytochrome P450-dependent transient receptor potential V4 activation in flow-induced vasodilatation

(2008) Annemarieke E. Loot et al.   CARDIOVASCULAR RESEARCH

Fate Tracing Reveals the Endothelial Origin of Hematopoietic Stem Cells

(2008) Ann C. Zovein et al.   Cell Stem Cell

Endothelial Cilia Are Fluid Shear Sensors That Regulate Calcium Signaling and Nitric Oxide Production Through Polycystin-1

(2008) Surya M. Nauli et al.   CIRCULATION

Complex cell rearrangements during intersegmental vessel sprouting and vessel fusion in the zebrafish embryo

(2008) Yannick Blum et al.   DEVELOPMENTAL BIOLOGY

Loss of unc45a precipitates arteriovenous shunting in the aortic arches

(2008) Matthew J. Anderson et al.   DEVELOPMENTAL BIOLOGY

miR-126 Regulates Angiogenic Signaling and Vascular Integrity

(2008) Jason E. Fish et al.   DEVELOPMENTAL CELL

Primary cilia sensitize endothelial cells for fluid shear stress

(2008) Beerend P. Hierck et al.   DEVELOPMENTAL DYNAMICS

Fluid shear stress induces arterial differentiation of endothelial progenitor cells

(2008) Syotaro Obi et al.   JOURNAL OF APPLIED PHYSIOLOGY

Neonatal Aortic Arch Hemodynamics and Perfusion During Cardiopulmonary Bypass

(2008) Onur Dur   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

Remodeling of conduit arteries in hypertension and flow-overload obeys a minimum energy principle

(2008) Wei Zhang et al.   JOURNAL OF BIOMECHANICS

Nuclear mechanotransduction: Response of the lamina to extracellular stress with implications in aging

(2008) Julia T. Philip et al.   JOURNAL OF BIOMECHANICS

Crucial role of nitric oxide synthases system in endothelium-dependent hyperpolarization in mice

(2008) Aya Takaki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Changes in wall motion and blood flow in the outflow tract of chick embryonic hearts observed with optical coherence tomography after outflow tract banding and vitelline-vein ligation

(2008) Sandra Rugonyi et al.   PHYSICS IN MEDICINE AND BIOLOGY

Serial analysis of the vascular endothelial transcriptome under static and shear stress conditions

(2008) Tian Jiao Chu et al.   PHYSIOLOGICAL GENOMICS

Endothelial primary cilia in areas of disturbed flow are at the base of atherosclerosis

(2007) Kim Van der Heiden et al.   ATHEROSCLEROSIS