Scaffold architecture determines chondrocyte response to externally applied dynamic compression

Chondrocytes and bone marrow-derived mesenchymal stem cells undergoing chondrogenesis in agarose hydrogels of solid and channelled architectures respond differentially to dynamic culture conditions

(2011) Eamon J. Sheehy et al.   Journal of Tissue Engineering and Regenerative Medicine

The Response of Bone Marrow-Derived Mesenchymal Stem Cells to Dynamic Compression Following TGF-β3 Induced Chondrogenic Differentiation

(2010) Stephen D. Thorpe et al.   ANNALS OF BIOMEDICAL ENGINEERING

The influence of biological motifs and dynamic mechanical stimulation in hydrogel scaffold systems on the phenotype of chondrocytes

(2010) Taly P. Appelman et al.   BIOMATERIALS

Validation of theoretical framework explaining active solute uptake in dynamically loaded porous media

(2010) Michael B. Albro et al.   JOURNAL OF BIOMECHANICS

Dynamic loading stimulates chondrocyte biosynthesis when encapsulated in charged hydrogels prepared from poly(ethylene glycol) and chondroitin sulfate

(2009) Idalis Villanueva et al.   MATRIX BIOLOGY

Engineering of Large Cartilaginous Tissues Through the Use of Microchanneled Hydrogels and Rotational Culture

(2009) Conor T. Buckley et al.   TISSUE ENGINEERING PART A

Gene expression profiles of dynamically compressed single chondrocytes and chondrons

(2008) Qi Guang Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The differential effect of scaffold composition and architecture on chondrocyte response to mechanical stimulation

(2008) Taly P. Appelman et al.   BIOMATERIALS

The effect of concentration, thermal history and cell seeding density on the initial mechanical properties of agarose hydrogels

(2008) Conor T. Buckley et al.   Journal of the Mechanical Behavior of Biomedical Materials

Static and dynamic compressive strains influence nitric oxide production and chondrocyte bioactivity when encapsulated in PEG hydrogels of different crosslinking densities

(2008) I. Villanueva et al.   OSTEOARTHRITIS AND CARTILAGE

Influence of decreasing nutrient path length on the development of engineered cartilage

(2008) L. Bian et al.   OSTEOARTHRITIS AND CARTILAGE

Analysis of radial variations in material properties and matrix composition of chondrocyte-seeded agarose hydrogel constructs

(2008) T.-A.N. Kelly et al.   OSTEOARTHRITIS AND CARTILAGE

Designing 3D Photopolymer Hydrogels to Regulate Biomechanical Cues and Tissue Growth for Cartilage Tissue Engineering

(2008) Stephanie J. Bryant et al.   PHARMACEUTICAL RESEARCH