HNF4α: a new biomarker in colon cancer?

Src tyrosine kinase phosphorylation of nuclear receptor HNF4  correlates with isoform-specific loss of HNF4  in human colon cancer

(2012) K. Chellappa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An HNF4α-miRNA Inflammatory Feedback Circuit Regulates Hepatocellular Oncogenesis

(2011) Maria Hatziapostolou et al.   CELL

Clinicopathological correlates and prognostic significance of glutathione S-transferase Pi expression in 468 patients after potentially curative resection of node-positive colonic cancer

(2011) King L Tan et al.   HISTOPATHOLOGY

A High Resolution Genome-Wide Scan of HNF4α Recognition Sites Infers a Regulatory Gene Network in Colon Cancer

(2011) Fridtjof Weltmeier et al.   PLoS One

Hepatocyte Nuclear Factor-4  Promotes Gut Neoplasia in Mice and Protects against the Production of Reactive Oxygen Species

(2010) M. Darsigny et al.   CANCER RESEARCH

Mapping of HNF4α target genes in intestinal epithelial cells

(2009) Mette Boyd et al.   BMC GASTROENTEROLOGY

Hepatocyte Nuclear Factor 4 , a Key Factor for Homeostasis, Cell Architecture, and Barrier Function of the Adult Intestinal Epithelium

(2009) A.-L. Cattin et al.   MOLECULAR AND CELLULAR BIOLOGY

Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region

(2009) Jeffrey C Barrett et al.   NATURE GENETICS

Identification of an Endogenous Ligand Bound to a Native Orphan Nuclear Receptor

(2009) Xiaohui Yuan et al.   PLoS One

Loss of Hepatocyte-Nuclear-Factor-4α Affects Colonic Ion Transport and Causes Chronic Inflammation Resembling Inflammatory Bowel Disease in Mice

(2009) Mathieu Darsigny et al.   PLoS One

EPS15R, TASP1, and PRPF3 Are Novel Disease Candidate Genes Targeted by HNF4α Splice Variants in Hepatocellular Carcinomas

(2008) Monika Niehof et al.   GASTROENTEROLOGY

Differentiation therapy of hepatocellular carcinoma in mice with recombinant adenovirus carrying hepatocyte nuclear factor-4α gene

(2008) Chuan Yin et al.   HEPATOLOGY

Hepatocyte nuclear factor 4α in the intestinal epithelial cells protects against inflammatory bowel disease

(2008) Sung-Hoon Ahn et al.   INFLAMMATORY BOWEL DISEASES

Inhibition of colorectal cancer by targeting hepatocyte nuclear factor-4α

(2008) Betty Schwartz et al.   INTERNATIONAL JOURNAL OF CANCER