Host genetics in immune-mediated hepatitis C virus clearance

Association of a single nucleotide polymorphism near the interleukin-28B gene with response to hepatitis C therapy in HIV/hepatitis C virus-coinfected patients

(2010) Norma I Rallón et al.   AIDS

The potential use of Toll-like receptor agonists to restore the dysfunctional immunity induced by hepatitis C virus

(2010) Mohamed L. Salem et al.   CELLULAR IMMUNOLOGY

Unique Th1/Th2 Phenotypes Induced during Priming and Memory Phases by Use of Interleukin-12 (IL-12) or IL-28B Vaccine Adjuvants in Rhesus Macaques

(2010) M. P. Morrow et al.   Clinical and Vaccine Immunology

The recent breakthroughs in the understanding of host genomics in hepatitis C

(2010) Andri Rauch et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

An IL28B Polymorphism Determines Treatment Response of Hepatitis C Virus Genotype 2 or 3 Patients Who Do Not Achieve a Rapid Virologic Response

(2010) Alessandra Mangia et al.   GASTROENTEROLOGY

A Polymorphism Near IL28B Is Associated With Spontaneous Clearance of Acute Hepatitis C Virus and Jaundice

(2010) Hans L. Tillmann et al.   GASTROENTEROLOGY

Replicated Association Between an IL28B Gene Variant and a Sustained Response to Pegylated Interferon and Ribavirin

(2010) Jeanette J. McCarthy et al.   GASTROENTEROLOGY

Genetic Variation in IL28B Is Associated With Chronic Hepatitis C and Treatment Failure: A Genome-Wide Association Study

(2010) Andri Rauch et al.   GASTROENTEROLOGY

Spontaneous Control of HCV Is Associated With Expression of HLA-B*57 and Preservation of Targeted Epitopes

(2010) Arthur Y. Kim et al.   GASTROENTEROLOGY

Natural killer cells and hepatitis C: action and reaction

(2010) K. Cheent et al.   GUT

IL28B genotype is associated with differential expression of intrahepatic interferon-stimulated genes in patients with chronic hepatitis C

(2010) Thomas J. Urban et al.   HEPATOLOGY

Amino acid substitution in hepatitis C virus core region and genetic variation near the interleukin 28B gene predict viral response to telaprevir with peginterferon and ribavirin

(2010) Norio Akuta et al.   HEPATOLOGY

Interleukin-28B genetic variants and hepatitis virus infection by different viral genotypes

(2010) Marco Antonio Montes-Cano et al.   HEPATOLOGY

Phase 1b study of pegylated interferon lambda 1 with or without ribavirin in patients with chronic genotype 1 hepatitis C virus infection

(2010) Andrew J. Muir et al.   HEPATOLOGY

Effect of immune pressure on hepatitis C virus evolution: Insights from a single-source outbreak

(2010) Shahzma Merani et al.   HEPATOLOGY

HLA class I allele associations with HCV genetic variants in patients with chronic HCV genotypes 1a or 1b infection

(2010) Christian Markus Lange et al.   JOURNAL OF HEPATOLOGY

Importance of IL28B gene polymorphisms in hepatitis C virus genotype 2 and 3 infected patients

(2010) Christoph Sarrazin et al.   JOURNAL OF HEPATOLOGY

Predictive value of the IL28B polymorphism on the effect of interferon therapy in chronic hepatitis C patients with genotypes 2a and 2b

(2010) Tomokazu Kawaoka et al.   JOURNAL OF HEPATOLOGY

IL-28B/IFN-λ3 Drives Granzyme B Loading and Significantly Increases CTL Killing Activity in Macaques

(2010) Matthew P Morrow et al.   MOLECULAR THERAPY

Association of Human Leucocyte Antigen Class I (HLA-A and HLA-B) With Chronic Hepatitis C Virus Infection in Egyptian Patients

(2010) Y. M. Mosaad et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Coexpression of PD-1, 2B4, CD160 and KLRG1 on Exhausted HCV-Specific CD8+ T Cells Is Linked to Antigen Recognition and T Cell Differentiation

(2010) Bertram Bengsch et al.   PLoS Pathogens

Comparative ability of IL-12 and IL-28B to regulate Treg populations and enhance adaptive cellular immunity

(2009) M. P. Morrow et al.   BLOOD

Divergent adaptation of hepatitis C virus genotypes 1 and 3 to human leukocyte antigen-restricted immune pressure

(2009) Andri Rauch et al.   HEPATOLOGY

Degree of cross-genotype reactivity of hepatitis C virus-specific CD8+ T cells directed against NS3

(2009) Silvia Giugliano et al.   HEPATOLOGY

Protective effect of human leukocyte antigen B27 in hepatitis C virus infection requires the presence of a genotype-specific immunodominant CD8+ T-cell epitope

(2009) Christoph Neumann-Haefelin et al.   HEPATOLOGY

Specific human leukocyte antigen class I and II alleles associated with hepatitis C virus viremia

(2009) Mark H. Kuniholm et al.   HEPATOLOGY

Consistent beneficial effects of killer cell immunoglobulin-like receptor 2DL3 and group 1 human leukocyte antigen-C following exposure to hepatitis C virus

(2009) Susanne Knapp et al.   HEPATOLOGY

Hepatitis C virus versus innate and adaptive immune responses: a tale of coevolution and coexistence

(2009) Barbara Rehermann   JOURNAL OF CLINICAL INVESTIGATION

Intracellular Innate Immune Cascades and Interferon Defenses That Control Hepatitis C Virus

(2009) Stacy M. Horner et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Regulatory T cells and viral liver disease

(2009) Nadia Alatrakchi et al.   JOURNAL OF VIRAL HEPATITIS

Effect of Killer Immunoglobulin-Like Receptors in the Response to Combined Treatment in Patients with Chronic Hepatitis C Virus Infection

(2009) J. R. Vidal-Castineira et al.   JOURNAL OF VIROLOGY

Alpha Interferon Induces Long-Lasting Refractoriness of JAK-STAT Signaling in the Mouse Liver through Induction of USP18/UBP43

(2009) M. Sarasin-Filipowicz et al.   MOLECULAR AND CELLULAR BIOLOGY

Protective KIR–HLA interactions for HCV infection in intravenous drug users

(2009) Joaquín Zúñiga et al.   MOLECULAR IMMUNOLOGY

Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

(2009) Dongliang Ge et al.   NATURE

Genetic variation in IL28B and spontaneous clearance of hepatitis C virus

(2009) David L. Thomas et al.   NATURE

IL28B is associated with response to chronic hepatitis C interferon-α and ribavirin therapy

(2009) Vijayaprakash Suppiah et al.   NATURE GENETICS

Genome-wide association of IL28B with response to pegylated interferon-α and ribavirin therapy for chronic hepatitis C

(2009) Yasuhito Tanaka et al.   NATURE GENETICS

Host genetic determinants of spontaneous hepatitis C clearance

(2009) Andri Rauch et al.   PHARMACOGENOMICS

Ethnic and geographical differences in HLA associations with the outcome of hepatitis C virus infection

(2009) Jane H Wang et al.   Virology Journal

Adaptive immune responses to hepatitis C virus: from viral immunobiology to a vaccine

(2008) Robert Thimme et al.   BIOLOGICAL CHEMISTRY

Hepatitis C and Innate Immunity: Recent Advances

(2008) Gyongyi Szabo et al.   Clinics in Liver Disease

Virological and immunological determinants of intrahepatic virus-specific CD8+ T-cell failure in chronic hepatitis C virus infection

(2008) Christoph Neumann-Haefelin et al.   HEPATOLOGY

Human leukocyte antigen class II associations with hepatitis C virus clearance and virus‐specific CD4 T cell response among Caucasians and African Americans

(2008) Rebecca A. Harris et al.   HEPATOLOGY

Genetic Markers of IgG Influence the Outcome of Infection with Hepatitis C Virus

(2008) Janardan P. Pandey et al.   JOURNAL OF INFECTIOUS DISEASES

Interaction of NK inhibitory receptor genes with HLA-C and MHC class II alleles in Hepatitis C virus infection outcome

(2008) Viviana Romero et al.   MOLECULAR IMMUNOLOGY

Interferon signaling and treatment outcome in chronic hepatitis C

(2008) M. Sarasin-Filipowicz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IFN-Lambda (IFN-λ) Is Expressed in a Tissue-Dependent Fashion and Primarily Acts on Epithelial Cells In Vivo

(2008) Caroline Sommereyns et al.   PLoS Pathogens