Genomic and metabolomic advances in the identification of disease and adverse event biomarkers

From differentiating metabolites to biomarkers

(2009) Albert Koulman et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Clinical Applications of Metabolomics in Oncology: A Review

(2009) J. L. Spratlin et al.   CLINICAL CANCER RESEARCH

Translational Toxicology and the Work of the Predictive Safety Testing Consortium

(2009) WB Mattes et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

A Metabonomic Study on the Biochemical Effects of Doxorubicin in Rats Using1H-NMR Spectroscopy

(2009) Jong-Chul Park et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression

(2009) Arun Sreekumar et al.   NATURE

Circulating microRNAs, potential biomarkers for drug-induced liver injury

(2009) K. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pharmacogenomics, Evidence, and the Role of Payers

(2009) P.A. Deverka   Public Health Genomics

Discovery of Metabolomics Biomarkers for Early Detection of Nephrotoxicity

(2009) Kurt J. Boudonck et al.   TOXICOLOGIC PATHOLOGY

Utility of magnetic resonance imaging and nuclear magnetic resonance-based metabolomics for quantification of inflammatory lung injury

(2008) Natalie J. Serkova et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Metabolomic Biomarkers in a Model of Asthma Exacerbation

(2008) Erik J. Saude et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry for metabonomics: Biomarker discovery for diabetes mellitus

(2008) Xiang Li et al.   ANALYTICA CHIMICA ACTA

Metabolomics: A Global Biochemical Approach to Drug Response and Disease

(2008) Rima Kaddurah-Daouk et al.   Annual Review of Pharmacology and Toxicology

Biomarkers of tissue injury

(2008) Omar F Laterza et al.   Biomarkers in Medicine

Mass spectrometry based metabolomic approaches in urinary biomarker study of women's cancers

(2008) Han Min Woo et al.   CLINICA CHIMICA ACTA

Bioinformatics Analysis of Targeted Metabolomics—Uncovering Old and New Tales of Diabetic Mice under Medication

(2008) Elisabeth Altmaier et al.   ENDOCRINOLOGY

Multigene Analysis Can Discriminate Between Ulcerative Colitis, Crohn's Disease, and Irritable Bowel Syndrome

(2008) Petra von Stein et al.   GASTROENTEROLOGY

Alzheimer's disease beyond the genomic era: nuclear magnetic resonance (NMR) spectroscopy-based metabolomics

(2008) Ignasi Barba et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Gene Expression in Peripheral Blood Differs after Cardioembolic Compared with Large-Vessel Atherosclerotic Stroke: Biomarkers for the Etiology of Ischemic Stroke

(2008) Huichun Xu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Metabonomics evaluation of urine from rats given acute and chronic doses of acetaminophen using NMR and UPLC/MS

(2008) Jinchun Sun et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Metabolic Profiling of Human Colorectal Cancer Using High-Resolution Magic Angle Spinning Nuclear Magnetic Resonance (HR-MAS NMR) Spectroscopy and Gas Chromatography Mass Spectrometry (GC/MS)

(2008) Eric Chun Yong Chan et al.   JOURNAL OF PROTEOME RESEARCH

Nuclear magnetic resonance-based metabolomics predicts exercise-induced ischemia in patients with suspected coronary artery disease

(2008) Ignasi Barba et al.   MAGNETIC RESONANCE IN MEDICINE

Urine Metabolomics Analysis for Kidney Cancer Detection and Biomarker Discovery

(2008) Kyoungmi Kim et al.   MOLECULAR & CELLULAR PROTEOMICS

RNA-Seq: a revolutionary tool for transcriptomics

(2008) Zhong Wang et al.   NATURE REVIEWS GENETICS

Metabonomics of acute kidney injury in children after cardiac surgery

(2008) Richard D. Beger et al.   PEDIATRIC NEPHROLOGY

Metabolic Profiling as a Tool for Understanding Mechanisms of Toxicity

(2008) Christopher J. Clarke et al.   TOXICOLOGIC PATHOLOGY

Interlaboratory Evaluation of Genomic Signatures for Predicting Carcinogenicity in the Rat

(2008) Mark R. Fielden et al.   TOXICOLOGICAL SCIENCES

Detection of Cell-Free, Liver-Specific mRNAs in Peripheral Blood from Rats with Hepatotoxicity: A Potential Toxicological Biomarker for Safety Evaluation

(2008) Makoto Miyamoto et al.   TOXICOLOGICAL SCIENCES

Strategic paths for biomarker qualification

(2008) Federico M. Goodsaid et al.   TOXICOLOGY

Metabolic profiling studies on the toxicological effects of realgar in rats by 1H NMR spectroscopy

(2008) Lai Wei et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Evaluations of the trans-sulfuration pathway in multiple liver toxicity studies

(2008) Laura K. Schnackenberg et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Quantitative metabolomics using NMR

(2008) David S. Wishart   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Applications of Metabolomics in Drug Discovery and Development

(2008) David S Wishart   Drugs in research & development

Age‐related differences in susceptibility to toxic effects of valproic acid in rats

(2007) Parvaneh Espandiari et al.   JOURNAL OF APPLIED TOXICOLOGY

Aristolochic acid induced changes in the metabolic profile of rat urine

(2007) Wan Chan et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Toxicological effects of cinnabar in rats by NMR-based metabolic profiling of urine and serum

(2007) Lai Wei et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY