Use of genome-wide high-throughput technologies in biomarker development

The FDA Critical Path Initiative and Its Influence on New Drug Development

(2008) Janet Woodcock et al.   Annual Review of Medicine

Metabolomics: A Global Biochemical Approach to Drug Response and Disease

(2008) Rima Kaddurah-Daouk et al.   Annual Review of Pharmacology and Toxicology

Approaches to working in high-dimensional data spaces: gene expression microarrays

(2008) Y Wang et al.   BRITISH JOURNAL OF CANCER

How Large a Training Set is Needed to Develop a Classifier for Microarray Data?

(2008) K. K. Dobbin et al.   CLINICAL CANCER RESEARCH

MDM2 SNP309 Is Associated With Poor Outcome in B-Cell Chronic Lymphocytic Leukemia

(2008) Irina Gryshchenko et al.   JOURNAL OF CLINICAL ONCOLOGY

Biomarker Developers Face Big Hurdles

(2008) R. S. Tuma   JNCI-Journal of the National Cancer Institute

Correlation network analysis for data integration and biomarker selection

(2008) Aram Adourian et al.   Molecular BioSystems

A variant associated with nicotine dependence, lung cancer and peripheral arterial disease

(2008) Thorgeir E. Thorgeirsson et al.   NATURE

A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25

(2008) Rayjean J. Hung et al.   NATURE

Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1

(2008) Christopher I Amos et al.   NATURE GENETICS

Genome-wide association studies: progress and potential for drug discovery and development

(2008) Stephen F. Kingsmore et al.   NATURE REVIEWS DRUG DISCOVERY

Biomarkers of Acute Kidney Injury

(2007) Vishal S. Vaidya et al.   Annual Review of Pharmacology and Toxicology

New blood-based biomarkers for the diagnosis, staging and prognosis of prostate cancer

(2007) Shahrokh F. Shariat et al.   BJU INTERNATIONAL

Interlaboratory Performance of a Microarray-Based Gene Expression Test to Determine Tissue of Origin in Poorly Differentiated and Undifferentiated Cancers

(2007) Catherine I. Dumur et al.   JOURNAL OF MOLECULAR DIAGNOSTICS